Mutations of Profilin‑1 Associated with Amyotrophic Lateral Sclerosis Promote Aggregation Due to Structural Changes of Its Native State

2015 / ACS Chemical Biology

The PFN1 gene, coding for profilin-1, has recently been associated with familial amyotrophic lateral sclerosis (fALS), as three mutations, namely… Continue reading Mutations of Profilin‑1 Associated with Amyotrophic Lateral Sclerosis Promote Aggregation Due to Structural Changes of Its Native State

Leah Pandiscia, PhD

Calcium Phosphate Mineralization in Cellulose Derivative/ Poly(acrylic acid) Composites Having a Chiral Nematic Mesomorphic Structure

2015 / Biomacromolecules

Calcium phosphate mineralization was conducted by using polymer composites of liquid-crystalline (ethyl)cellulose (EC) or (hydroxypropyl)cellulose (HPC) with poly(acrylic acid) (PAA)… Continue reading Calcium Phosphate Mineralization in Cellulose Derivative/ Poly(acrylic acid) Composites Having a Chiral Nematic Mesomorphic Structure

Leah Pandiscia, PhD

Ordered DNA-Surfactant Hybrid Nanospheres Triggered by Magnetic Cationic Surfactants for Photon- and Magneto-Manipulated Drug Delivery and Release

2015 / Biomacromolecules

Here we construct for the first time ordered surfactant–DNA hybrid nanospheres of double-strand (ds) DNA and cationic surfactants with magnetic… Continue reading Ordered DNA-Surfactant Hybrid Nanospheres Triggered by Magnetic Cationic Surfactants for Photon- and Magneto-Manipulated Drug Delivery and Release

Leah Pandiscia, PhD

Complementary Effects of Host Defense Peptides Piscidin 1 and Piscidin 3 on DNA and Lipid Membranes: Biophysical Insights into Contrasting Biological Activities

2015 / Journal Physical Chemistry B

Piscidins were the first antimicrobial peptides discovered in the mast cells of vertebrates. While two family members, piscidin 1 (p1)… Continue reading Complementary Effects of Host Defense Peptides Piscidin 1 and Piscidin 3 on DNA and Lipid Membranes: Biophysical Insights into Contrasting Biological Activities

Leah Pandiscia, PhD

Spontaneous Formation of Multiarchitecture Vesicles of [C8mim]Br + [Na]DBS in Aqueous Medium: Synergic Interplay of Electrostatic, Hydrophobic, and π−π Stacking Interactions

2015 / Journal Physical Chemistry B

A mixture of a cationic surface active ionic liquid, [C8mim]Br and anionic surfactant, [Na]DBS has been shown to form unilamellar… Continue reading Spontaneous Formation of Multiarchitecture Vesicles of [C8mim]Br + [Na]DBS in Aqueous Medium: Synergic Interplay of Electrostatic, Hydrophobic, and π−π Stacking Interactions

Leah Pandiscia, PhD