2020 / International Journal of Biological Macromolecules
Glycation is a non-enzymatic reaction between carbonyl groups in sugar and free amino groups in proteins. This reaction leads to… Continue reading Study of glycation process of human carbonic anhydrase II as well as investigation concerning inhibitory influence of 3-beta-hydroxybutyrate on it
2020 / Chemical Physics Letters
We report the interaction between a well-known antibiotic chloramphenicol (Clp) and the protein, bovine pancreatic trypsin. Both steady-state and time-resolved… Continue reading On the role of hydrophobic interactions between chloramphenicol and bovine pancreatic trypsin: The effect of a strong electrolyte
2020 / Journal of Controlled Release
The conventional active-targeting nano-chemotherapy suffers from poor tumor tissue penetration and nonnegligible toxicity due to the size/ligand dilemmas and insufficient… Continue reading Size-adaptable and ligand (biotin)-sheddable nanocarriers equipped with avidin scavenging technology for deep tumor penetration and reduced toxicity
2020 / Journal of Drug Delivery Science and Technology
In this study, the hydrophobic drug Tanshinone ⅡA (Tan ⅡA) as a therapeutic drug was loaded into naphthalene acetic acid-phenylalanine-phenylalanine-glycine… Continue reading A simple injectable peptide-based hydrogel of tanshinone ⅡA for antioxidant and anticoagulation
2020 / Food Chemistry
Protein glycation plays a vital role in the progression of various diabetes complications. Therefore, inhibition of protein glycation could be… Continue reading Inhibition of protein glycoxidation and advanced glycation end-product formation by barnyard millet (Echinochloa frumentacea) phenolics
2020 / Biochemical and Biophysical Research Communications
Ferritins are ubiquitous iron-binding proteins that are mainly related to iron storage, detoxification and innate immunity. Here, we present the… Continue reading Crystallographic characterization of ferritin from Sinonovacula constricta
2020 / International Journal of Biological Macromolecules
Pyruvate dehydrogenase kinase-3 (PDK3) plays important role in the glucose metabolism and is associated with cancer progression, and thus being… Continue reading Effect of pH on the structure and function of pyruvate dehydrogenase kinase 3: Combined spectroscopic and MD simulation studies
2020 / Journal of Rare Earths
The enantiomers of carboline-based cryptates were successfully resolved by chiral HPLC. These complexes show high configurational stability under harsh conditions… Continue reading Circularly polarized luminescence of enantiopure carboline-based europium cryptates under visible light excitation
2020 / Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
Puerariae Radix (PR) is a natural herb whose active ingredient is mainly flavonoids. To explore the interaction between PR flavonoids… Continue reading Comprehensive study of the interaction between Puerariae Radix flavonoids and DNA: From theoretical simulation to structural analysis to functional analysis
2020 / Food Hydrocolloids
The conformation and physicochemical attributes of proteins play important roles in determining their flexibility. This study investigates the structural flexibility… Continue reading The investigation of protein flexibility of various soybean cultivars in relation to physicochemical and conformational properties
2020 / Tetrahedron
Four new oxaphenalenone dimers (bacillisporins I and J, duclauxamides B and C) together with four known compounds (bacillisporins A –… Continue reading Heptacyclic oligophenalenones from the soil fungus Talaromyces bacillisporus BCC17645
2020 / Journal of Physical Chemistry A
Partially overlapped dicarbazolophanes exhibit a planar chirality. In this study, C2-symmetrical [3.3](3,9)dicarbazolophane derivatives (CZ1–CZ3) have been optically resolved by preparative chiral… Continue reading Combined Experimental and Theoretical Studies on Planar Chirality of Partially Overlapped C2-Symmetric [3.3](3,9)Dicarbazolophanes
2020 / Scientific Reports
The glycopeptide antibiotic vancomycin has been widely used to treat infections of Gram-positive bacteria including Clostridium difficile and methicillin-resistant Staphylococcus aureus. However, since… Continue reading The Extracellular Domain of Two-component System Sensor Kinase VanS from Streptomyces coelicolor Binds Vancomycin at a Newly Identified Binding Site
2019 / ACG Publications
Analysis of the MeOH extract of rhizomes of Sansevieria cylindrica using repeated silica gel and reversed-phase chromatographic separations led to… Continue reading Bioactive Constituents from the Rhizomes of Sansevieria cylindrica
2020 / Chirality, Volume 32, Issue5 May 2020 Pages 704-709
Chiroptical materials have received much attention in diverse fields for applications such as displays, sensors, smart memory devices, and catalysis.… Continue reading Chiroptical property tuning of supramolecular assemblies in polymer matrices
2020 / Science Direct, Fitoterapia Volume 143, June 2020, 104551
Five new alkaloids (1–5), including three new aporphine alkaloids and two new phenanthrene alkaloids, together with 10 known compounds (6–15)… Continue reading Aporphine and phenanthrene alkaloids with antioxidant activity from the roots of Stephania tetrandra
2020 / Biophysical Journal ARTICLE | VOLUME 118, ISSUE 7, P1665-1678, APRIL 07, 2020
We have developed a computational method of atomistically refining the structural ensemble of intrinsically disordered peptides (IDPs) facilitated by experimental… Continue reading Molecular Dynamics Ensemble Refinement of Intrinsically Disordered Peptides According to Deconvoluted Spectra from Circular Dichroism
2020 / Cold Spring Harbor Laboratory - Preprint
The dependence of the host on the interaction of hundreds of extracellular proteins with the cell surface glycosaminoglycan heparan sulphate… Continue reading SARS-CoV-2 Spike S1 Receptor Binding Domain undergoes Conformational Change upon Interaction with Low Molecular Weight Heparins
2013 / FEBS Letters
The coronavirus (CoV) N protein oligomerizes via its carboxyl terminus. However, the oligomerization mechanism of the C-terminal domains (CTD) of… Continue reading Oligomerization of the carboxyl terminal domain of the human coronavirus 229E nucleocapsid protein
2006 / Biochemical and Biophysical Research Communications
Human coronavirus 229E (HCoV-229E), a member of group I coronaviruses, has been identified as one of the major viral agents causing respiratory… Continue reading Characterization of HCoV-229E fusion core: Implications for structure basis of coronavirus membrane fusion
