Circular Dichroism Archives

Interaction of Quillaja bark saponin and bovine serum albumin: Effect on secondary and tertiary structure, gelation and in vitro digestibility of the protein

2020 / LWT

The interaction of Quillaja bark saponin and bovine serum albumin was determined by isothermal titration calorimetry and correlated to the structure, gelation… Continue reading Interaction of Quillaja bark saponin and bovine serum albumin: Effect on secondary and tertiary structure, gelation and in vitro digestibility of the protein

Not sequentially but simultaneously: Facile extraction of proteins and oleosomes from oilseeds

2020 / Food Hydrocolloids

The interaction of Quillaja bark saponin and bovine serum albumin was determined by isothermal titration calorimetry and correlated to the structure, gelation… Continue reading Not sequentially but simultaneously: Facile extraction of proteins and oleosomes from oilseeds

The amplified circularly polarized luminescence regulated from D–A type AIE-active chiral emitters via liquid crystals system

2020 / Chemical Communications

Two pairs of D–A type AIE-active chiral dyes (R-/S-1 and R-/S-2) as chiral emitters doped into nematic liquid crystals (5CB, N-LCs)… Continue reading The amplified circularly polarized luminescence regulated from D–A type AIE-active chiral emitters via liquid crystals system

In Silico Discovery and Validation of Neuropeptide-Y-Binding Peptides for Sensors

2020 / Journal of Physical Chemistry B

Wearable sensors for human health, performance, and state monitoring, which have a linear response to the binding of biomarkers found… Continue reading In Silico Discovery and Validation of Neuropeptide-Y-Binding Peptides for Sensors

Development of cell-permeable peptide-based PROTACs targeting estrogen receptor α

2020 / European Journal of Medicinal Chemistry

Proteolysis-targeting chimera (PROTAC) could selectively degrade target protein and may become a promising strategy for treating estrogen receptor α (ERα)… Continue reading Development of cell-permeable peptide-based PROTACs targeting estrogen receptor α

Neat Ionic liquid and α-Chymotrypsin-Polymer Surfactant Conjugate-Based Biocatalytic Solvent

2020 / Biomacromolecules

Performing biocatalysis in nonaqueous solvents is advantageous as it imparts enhanced solubility to hydrophobic substrates and an ability to increase… Continue reading Neat Ionic liquid and α-Chymotrypsin-Polymer Surfactant Conjugate-Based Biocatalytic Solvent

Unravelling the distinctive mode of cooperative and independent interaction mechanism of 1-butyl-2,3-dimethylimidazolium tetrafluoroborate ionic liquid with model transport proteins by comprehensive spectroscopic and computational studies

2020 / Journal of Molecular Structure

In the present investigation, a detailed spectroscopic analysis on the interaction mechanism of 1-Butyl-2,3-dimethylimidazolium tetrafluoroborate [Bdmim][BF4] with human serum albumin… Continue reading Unravelling the distinctive mode of cooperative and independent interaction mechanism of 1-butyl-2,3-dimethylimidazolium tetrafluoroborate ionic liquid with model transport proteins by comprehensive spectroscopic and computational studies

Enantiodivergent syntheses of (+)- and (−)-1-(2,6-dimethylphenoxy)propan-2-ol: A way to access (+)- and (−)-mexiletine from D-(+)-mannitol

2020 / Carbohydrate Research

Chiron approach was used to acquire optically pure (R)- and (S)-1-(2,6-dimethylphenoxy)propan-2-ol, immediate precursors of (S)- and (R)-mexiletines, respectively. Two different… Continue reading Enantiodivergent syntheses of (+)- and (−)-1-(2,6-dimethylphenoxy)propan-2-ol: A way to access (+)- and (−)-mexiletine from D-(+)-mannitol

Red, Orange, Green: Light- and Temperature-Dependent Color Tuning in a Cyanobacteriochrome

2020 / Biochemistry

Cyanobacteriochromes (CBCRs) are photoreceptor proteins that photoconvert between two parent states and thereby regulate various biological processes. An intriguing property… Continue reading Red, Orange, Green: Light- and Temperature-Dependent Color Tuning in a Cyanobacteriochrome

An Immune-Stimulatory Helix–Loop–Helix Peptide: Selective Inhibition of CTLA-4–B7 Interaction

2020 / ACS Chemical Biology

Molecular-targeting peptides and mini-proteins are promising alternatives to antibodies in a wide range of applications in bioscience and medicine. We… Continue reading An Immune-Stimulatory Helix–Loop–Helix Peptide: Selective Inhibition of CTLA-4–B7 Interaction

An artificial metalloenzyme biosensor can detect ethylene gas in fruits and Arabidopsis leaves

2019 / Nature Communications

Enzyme biosensors are useful tools that can monitor rapid changes in metabolite levels in real-time. However, current approaches are largely… Continue reading An artificial metalloenzyme biosensor can detect ethylene gas in fruits and Arabidopsis leaves

Effect of high-power sonication pretreatment on extraction and some physicochemical properties of proteins from chickpea, kidney bean, and soybean☆

2020 / International Journal of Biological Macromolecules

Impact of high-power sonication (HPS) as pretreatment in extraction and some physicochemical properties of proteins from soybean flakes, flour of… Continue reading Effect of high-power sonication pretreatment on extraction and some physicochemical properties of proteins from chickpea, kidney bean, and soybean☆

Structural and DNA binding properties of mycobacterial integration host factor mIHF

2020 / Journal of Structural Biology

In bacteria, nucleoid associated proteins (NAPs) take part in active chromosome organization by supercoil management, three-dimensional DNA looping and direct… Continue reading Structural and DNA binding properties of mycobacterial integration host factor mIHF

The flanking peptides issue from the maturation of the human islet amyloid polypeptide (hIAPP) slightly modulate hIAPP-fibril formation but not hIAPP-induced cell death

2020 / Biochimie

Type 2 diabetes mellitus is a disease characterized by the formation of amyloid fibrillar deposits consisting mainly in human islet… Continue reading The flanking peptides issue from the maturation of the human islet amyloid polypeptide (hIAPP) slightly modulate hIAPP-fibril formation but not hIAPP-induced cell death

The small molecule inhibitor anle145c thermodynamically traps human islet amyloid peptide in the form of non-cytotoxic oligomers

2019 / Scientific Reports

Type 2 diabetes (T2DM) is associated with aggregation of the human islet amyloid polypeptide (hIAPP) into cytotoxic amyloid species. Here… Continue reading The small molecule inhibitor anle145c thermodynamically traps human islet amyloid peptide in the form of non-cytotoxic oligomers

Purification of WAP domain-containing antimicrobial peptides from green tiger shrimp Peaneaus semisulcatus

2020 / Microbial Pathogenesis

Antimicrobial peptide crustin was isolated and purified from Penaeus semisulcatus using Sephadox G-100 column gel filtration chromatography. P. semisulcatus crustins was observed as a… Continue reading Purification of WAP domain-containing antimicrobial peptides from green tiger shrimp Peaneaus semisulcatus

Discovering Biomolecules with Huisgenase Activity: Designed Repeat Proteins as Biocatalysts for (3 + 2) Cycloadditions

2020 / JACS

Designed repeat proteins catalyze the 1,3-dipolar reaction between an imine and a π-deficient dipolarophile in THF solution to form unnatural… Continue reading Discovering Biomolecules with Huisgenase Activity: Designed Repeat Proteins as Biocatalysts for (3 + 2) Cycloadditions

Helical poly(phenyl isocyanide)s grafted selectively on C-6 of cellulose for improved chiral recognition ability

2020 / Carbohydrate Polymers

Cellulose graft copolymers are an effective way to endow new properties to cellulose substrate, as well the rigidity, regularity, and… Continue reading Helical poly(phenyl isocyanide)s grafted selectively on C-6 of cellulose for improved chiral recognition ability

Identification and functional characterization of the astacidin family of proline-rich host defence peptides (PcAst) from the red swamp crayfish (Procambarus clarkii, Girard 1852)

2020 / Developmental & Comparative Immunology

This study reports the identification of four novel proline-rich antimicrobial peptides (PR-AMP) from the transcriptome of the red swamp crayfish Procambarus… Continue reading Identification and functional characterization of the astacidin family of proline-rich host defence peptides (PcAst) from the red swamp crayfish (Procambarus clarkii, Girard 1852)

Purification, characterization and mode of action of enterocin, a novel bacteriocin produced by Enterococcus faecium TJUQ1