Circular Dichroism Archives

Conformational and lipid bilayer-perturbing properties of Marburg virus GP2 segments containing the fusion loop and membrane-proximal external region/transmembrane domain

2020 / Heliyon

Fusion of host and viral membranes is a crucial step during infection by enveloped viruses. In the structurally-defined “class I″… Continue reading Conformational and lipid bilayer-perturbing properties of Marburg virus GP2 segments containing the fusion loop and membrane-proximal external region/transmembrane domain

Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPase

2020 / biomolecules

AAA+ ATPase p97/valosin-containing protein (VCP)/Cdc48 is a key player in various cellular stress responses in which it unfolds ubiquitinated proteins… Continue reading Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPase

Unpacking the aggregation-oligomerization-fibrillization process of naturally-occurring hIAPP amyloid oligomers isolated directly from sera of children with obesity or diabetes mellitus

2019 / Scientific Reports

The formation of amyloid oligomers and fibrils of the human islet amyloid polypeptide (hIAPP) has been linked with β- cell… Continue reading Unpacking the aggregation-oligomerization-fibrillization process of naturally-occurring hIAPP amyloid oligomers isolated directly from sera of children with obesity or diabetes mellitus

Triplet of cysteines – Coordinational riddle?

2020 / Journal of Inorganic Biochemistry

Polythiol binding of metal ions plays crucial role in the proper functioning of cysteine-rich proteins that are responsible for metal… Continue reading Triplet of cysteines – Coordinational riddle?

In vitro digestibility, structural and functional properties of Moringa oleifera seed proteins

2020 / Food Hydrocolloids

The aim of this work was to compare the structural and functional properties of Moringa oleifera seed albumin and globulin with those… Continue reading In vitro digestibility, structural and functional properties of Moringa oleifera seed proteins

Heterotropic Modulation of Amylin Fibrillation by Small Molecules: Implications for Formulative Designs

2019 / The Protein Journal

Control of amylin agglomeration is of interest for both the study of pathophysiology and the design of amylin-based pharmaceutical products.… Continue reading Heterotropic Modulation of Amylin Fibrillation by Small Molecules: Implications for Formulative Designs

Homogenization pressure and soybean protein concentration impact the stability of perilla oil nanoemulsions

2020 / Food Hydrocolloids

Perilla oil (PO) nanoemulsions (PON) were prepared using different concentrations (2, 3, and 4%) of soybean protein isolate (SPI) at… Continue reading Homogenization pressure and soybean protein concentration impact the stability of perilla oil nanoemulsions

Interaction mechanism between α-glucosidase and A-type trimer procyanidin revealed by integrated spectroscopic analysis techniques

2020 / International Journal of Biological Macromolecules

α-Glucosidase is an important enzyme in human intestine, and inhibition of its activity can lower blood sugar levels to effectively… Continue reading Interaction mechanism between α-glucosidase and A-type trimer procyanidin revealed by integrated spectroscopic analysis techniques

Trichothioneic acid, a new antioxidant compound produced by the fungal strain Trichoderma virens FKI-7573

2019 / Journal of Bioscience and Bioengineering

A new nitrogen-containing compound, trichothioneic acid, was discovered from the metabolites of fungal strain FKI-7573 using a mass spectrometry screening… Continue reading Trichothioneic acid, a new antioxidant compound produced by the fungal strain Trichoderma virens FKI-7573

The structure of a prokaryotic feruloyl-CoA hydratase-lyase from a lignin-degrading consortium with high oligomerization stability under extreme pHs

2020 / Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

In the context of increasing demand for renewable alternatives of fuels and chemicals, the valorization of lignin emerges as a… Continue reading The structure of a prokaryotic feruloyl-CoA hydratase-lyase from a lignin-degrading consortium with high oligomerization stability under extreme pHs

Porous Organic Nanocages CC3 and CC3–OH for Chiral Gas Chromatography

2020 / ACS Applied Nano Materials

Porous organic nanocages (POCs) have received great concern in diverse areas recently. However, a long reaction time as well as… Continue reading Porous Organic Nanocages CC3 and CC3–OH for Chiral Gas Chromatography

Structural studies of the MMP-3 interaction with triple-helical collagen introduce new roles for the enzyme in tissue remodelling

2019 / Scientific Reports

Matrix metalloproteinase-3 (MMP-3) participates in normal extracellular matrix turnover during embryonic development, organ morphogenesis and wound healing, and in tissue-destruction… Continue reading Structural studies of the MMP-3 interaction with triple-helical collagen introduce new roles for the enzyme in tissue remodelling

Chemical Syntheses and Biological Evaluation of CXCL14 and Its Site-Selectively Modified Methionine Sulfoxide-Containing Derivatives

2020 / Journal of Organic Chemistry

The access to methionine sulfoxide [Met(O)]-containing proteins is particularly valuable for studying this important type of post-translational modification (PTM). However,… Continue reading Chemical Syntheses and Biological Evaluation of CXCL14 and Its Site-Selectively Modified Methionine Sulfoxide-Containing Derivatives

Self-Assembly-Assisted Kinetically Controlled Papain-Catalyzed Formation of mPEG-b-Phe(Leu)x

2019 / biomolecules

Self-assembling peptide materials are promising next-generation materials with applications that include tissue engineering scaffolds, drug delivery, bionanomedicine, and enviro-responsive materials.… Continue reading Self-Assembly-Assisted Kinetically Controlled Papain-Catalyzed Formation of mPEG-b-Phe(Leu)x

Signatures of Specific DNA Binding by the AT-Rich Interaction Domain of BAF250a

2020 / Biochemistry

The AT-rich interaction domain (ARID) containing BAF250a is a subunit of the BAF-A class of SWI/SNF chromatin remodeling complexes. The… Continue reading Signatures of Specific DNA Binding by the AT-Rich Interaction Domain of BAF250a

Nano-encapsulated Escherichia coli Divisome Anchor ZipA, and in Complex with FtsZ

2019 / Scientific Reports

The E. coli membrane protein ZipA, binds to the tubulin homologue FtsZ, in the early stage of cell division. We isolated ZipA in… Continue reading Nano-encapsulated Escherichia coli Divisome Anchor ZipA, and in Complex with FtsZ

A multi-channel in situ light scattering instrument utilized for monitoring protein aggregation and liquid dense cluster formation

2020 / Heliyon

Liquid-liquid phase separation (LLPS) phenomena have been observed in vitro as well as in vivo and came in focus of interdisciplinary research activities particularly… Continue reading A multi-channel in situ light scattering instrument utilized for monitoring protein aggregation and liquid dense cluster formation

Ultra-thin free-floating carbon nanotube/gold nanoparticle hybrid film prepared with self-assembly protein of α-synuclein

2019 / Sensors and Actuators B: Chemical

Fabrication of ultra-thin 2D film of carbon nanotubes (CNTs) is achieved by employing a self-assembly protein of α-synuclein (αS). Electron… Continue reading Ultra-thin free-floating carbon nanotube/gold nanoparticle hybrid film prepared with self-assembly protein of α-synuclein

Binding of anticancer drug adriamycin to parallel G‐quadruplex DNA [d‐(TTAGGGT)]4 comprising human telomeric DNA leads to thermal stabilization: A multiple spectroscopy study

2019 / Journal of Molecular Recognition

Adriamycin is known to exert its anti cancer action by inhibiting DNA duplication, RNA transcription and topoisomerase‐II enzyme action. Recent… Continue reading Binding of anticancer drug adriamycin to parallel G‐quadruplex DNA [d‐(TTAGGGT)]4 comprising human telomeric DNA leads to thermal stabilization: A multiple spectroscopy study

In Situ Cyclization of Proteins (INCYPRO): Cross-Link Derivatization Modulates Protein Stability

2019 / The Journal of Organic Chemistry

Protein macrocyclization represents a very efficient strategy to increase the stability of protein tertiary structures. Here, we describe a panel… Continue reading In Situ Cyclization of Proteins (INCYPRO): Cross-Link Derivatization Modulates Protein Stability

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Conformational and lipid bilayer-perturbing properties of Marburg virus GP2 segments containing the fusion loop and membrane-proximal external region/transmembrane domain

Structure of the PUB Domain from Ubiquitin Regulatory X Domain Protein 1 (UBXD1) and Its Interaction with the p97 AAA+ ATPase

Unpacking the aggregation-oligomerization-fibrillization process of naturally-occurring hIAPP amyloid oligomers isolated directly from sera of children with obesity or diabetes mellitus

Triplet of cysteines – Coordinational riddle?

In vitro digestibility, structural and functional properties of Moringa oleifera seed proteins

Heterotropic Modulation of Amylin Fibrillation by Small Molecules: Implications for Formulative Designs

Homogenization pressure and soybean protein concentration impact the stability of perilla oil nanoemulsions

Interaction mechanism between α-glucosidase and A-type trimer procyanidin revealed by integrated spectroscopic analysis techniques

Trichothioneic acid, a new antioxidant compound produced by the fungal strain Trichoderma virens FKI-7573

The structure of a prokaryotic feruloyl-CoA hydratase-lyase from a lignin-degrading consortium with high oligomerization stability under extreme pHs

Porous Organic Nanocages CC3 and CC3–OH for Chiral Gas Chromatography

Structural studies of the MMP-3 interaction with triple-helical collagen introduce new roles for the enzyme in tissue remodelling

Chemical Syntheses and Biological Evaluation of CXCL14 and Its Site-Selectively Modified Methionine Sulfoxide-Containing Derivatives

Self-Assembly-Assisted Kinetically Controlled Papain-Catalyzed Formation of mPEG-b-Phe(Leu)x

Signatures of Specific DNA Binding by the AT-Rich Interaction Domain of BAF250a

Nano-encapsulated Escherichia coli Divisome Anchor ZipA, and in Complex with FtsZ

A multi-channel in situ light scattering instrument utilized for monitoring protein aggregation and liquid dense cluster formation

Ultra-thin free-floating carbon nanotube/gold nanoparticle hybrid film prepared with self-assembly protein of α-synuclein

Binding of anticancer drug adriamycin to parallel G‐quadruplex DNA [d‐(TTAGGGT)]4 comprising human telomeric DNA leads to thermal stabilization: A multiple spectroscopy study

In Situ Cyclization of Proteins (INCYPRO): Cross-Link Derivatization Modulates Protein Stability

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