2020 / Archives of Biochemistry and Biophysics
Crystallin proteins undergo various posttranslational modifications with aging of eye lens. Oxidation of tryptophan (Trp) residues of a major γ-crystallin… Continue reading Protective role of hesperetin against posttranslational oxidation of tryptophan residue of human γD-crystallin: A molecular level study
2020 / Bioorganic Chemistry
The development of 1,8-naphthalimide derivatives as DNA-targeting anticancer agents is a rapidly growing area and has resulted in several derivatives… Continue reading Synthesis of naphthalimide-carborane and metallacarborane conjugates: Anticancer activity, DNA binding ability
2019 / Scientific Reports
Circular dichroism (CD) signals revealed in some materials may arise from different origins during measurements. Magnetic field dependent CD (MCD)… Continue reading Extraction of magnetic circular dichroism effects from blended mixture of magnetic linear dichroism signals in the cobalt/Scotch tape system
2019 / Science Signaling
The stromal interaction molecule 1 (STIM1) has two important functions, Ca2+ sensing within the endoplasmic reticulum and activation of the store-operated… Continue reading Sequential activation of STIM1 links Ca2+ with luminal domain unfolding
2019 / Biomacromolecules
The therapeutic potential of protein drugs has been hindered by difficulties with long-term stability and rapid clearance from the body.… Continue reading Elucidating Molecular Design Principles for Charge-Alternating Peptides
2019 / International Journal of Biological Macromolecules
Dextran 70 and its building block (glucose) has been used as macromolecular crowder and osmolyte, respectively. The difference in size… Continue reading Molecular and macromolecular crowding-induced stabilization of proteins: Effect of dextran and its building block alone and their mixtures on stability and structure of lysozyme
2019 / International Journal of Peptide Research and Therapeutics
Lipopolysaccharide and β-1,3-glucan-binding protein (LGBP) is a pattern recognition protein (PRP) purified from the Penaeus monodon by Blue-Sepharose, Phenyl-Sepharose followed by Sephadex… Continue reading Effect of Amino Acid Substitution in the Penaeus monodon LGBP and Specificity Through Mutational Analysis
2020 / Genetics
Sequences encoding Olduvai protein domains (formerly DUF1220) show the greatest human lineage-specific increase in copy number of any coding region… Continue reading The Driver of Extreme Human-Specific Olduvai Repeat Expansion Remains Highly Active in the Human Genome
2020 / Steriods
Using a cell-based cytotoxicity assay, two new polyhydroxylated sterols, 16(S),22(S)-epoxy-3β,5α,6β,20(R),23(R),25-hexahydroxy-7-ergostene and 3β,7β,8α,25-tetrahydroxy-5,22E-ergostadiene were isolated from the ethyl acetate portion of… Continue reading Polyhydroxylated sterols from Monascus purpureus-fermented rice
2019 / International Journal of Biological Macromolecules
The present manuscript reports the synthesis and characterization of polymerizable ammonium-based ionic liquids (ILs) and explores their influence on structural… Continue reading A biophysical strategy to examine the impact of newly synthesized polymerizable ammonium-based ionic liquids on the structural stability and proteolytic activity of stem bromelain
2019 / International Journal of Biological Macromolecules
The inhibition of α-glucosidase activity is a prospective approach to prevent postprandial hyperglycemia. As two flavonoids extracted from citrus fruits,… Continue reading Spectroscopy and molecular docking analysis reveal structural specificity of flavonoids in the inhibition of α-glucosidase activity
2019 / Molecular Microbiology
Phosphorothioation (PT) involves the replacement of a nonbridging phosphate oxygen on the DNA backbone with sulfur. In bacteria, the procedure… Continue reading An in vitro DNA phosphorothioate modification reaction
2019 / Cells
LiTCTP is a toxin from the Translationally Controlled Tumor Protein (TCTP) family identified in Loxosceles brown spider venoms. These proteins are known… Continue reading TCTP from Loxosceles Intermedia (Brown Spider) Venom Contributes to the Allergic and Inflammatory Response of Cutaneous Loxoscelism
2020 / Materials Science and Engineering C
Controlling the self-assembly pathways through solvent mediated approach can be an effective means to create complex, multifunctional structures. However, predicting… Continue reading Tuning the gelation behavior of short laminin derived peptides via solvent mediated self-assembly
2019 / International Journal of Biological Macromolecules
The intracellular pathogen Mycobacterium tuberculosis can survive and replicate within host macrophages. Among various immunomodulatory substances, macrophages also produce α1-acid glycoprotein (AAG) which… Continue reading Interaction of antitubercular drug candidates with α1-acid glycoprotein produced in pulmonary granulomas
2020 / Journal of Inorganic Biochemistry
Bridge splitting reactions between [Pd(C2,N-dmba)(μ-X)]2 (dmba = N,N-dimethylbenzylamine; X = Cl, I, N3, NCO) and 2,6-lutidine (lut) in the 1:2 molar ratio at room temperature… Continue reading Cyclopalladated compounds containing 2,6-lutidine: Synthesis, spectral and biological studies
2020 / Food Chemistry
Simple and sensitive methods are required for the detection of melamine since melamine is harmful to human health. To detect… Continue reading Determination of melamine and melamine–Cu(II) complexes in milk using a DNA-Ag hydrocolloid as the sensor
2019 / ACS Sustainable Chemistry & Engineering
l-Asparaginase (ASNase) is a high value enzyme for the pharmaceutical and food industries. Although ionic liquids (ILs) have been recognized… Continue reading Enhancing the Biocatalytic Activity of l-Asparaginase Using Aqueous Solutions of Cholinium-Based Ionic Liquids
2019 / International Journal of Biological Macromolecules
Burkholderia pseudomallei and Chromobacterium violaceum are bacteria of tropical and subtropical soil and water that occasionally cause fatal infections in humans and animals.… Continue reading Characterization of novel lectins from Burkholderia pseudomallei and Chromobacterium violaceum with seven-bladed β-propeller fold
2020 / Journal of Molecular Liquids
This study explores the adsorption and binding interaction of bovine hemoglobin (BHb) and lysozyme (Lys) with gold/silver alloy nanoparticles (Au/Ag… Continue reading Insight into the binding and conformational changes of hemoglobin/lysozyme with bimetallic alloy nanoparticles using various spectroscopic approaches
