2020 / Food Hydrocolloids
β-lactoglobulin (β-Lg) has the ability to form three-dimensional networks when heated above denaturation temperature (ca. 76 °C), since it undergoes… Continue reading Suitability of β-lactoglobulin micro- and nanostructures for loading and release of bioactive compounds
2020 / The Journal of Organic Chemistry
Oxidative transformation of hexapyrrolylbenzenes into azacoronenes using bromine electrophiles as alternative coupling agents is shown to occur according to a… Continue reading Electrophilic Aromatic Coupling of Hexapyrrolylbenzenes. A Mechanistic Analysis
2020 / Phytochemistry Letters
Three new sulfated isoguanine alkaloid glycosides, locustoside A disulfate (1), saikachinoside B disulfate (2), and saikachinoside A trisulfate (3), have… Continue reading Rare sulfated purine alkaloid glycosides from Bruchidius dorsalis pupal case
2019 / FEBS Letters
14‐3‐3 proteins bind and modulate the activities of a wide variety of phosphoproteins. Crystal structures of 14‐3‐3 isoforms bound to… Continue reading Two negatively charged invariant residues influence ligand binding and conformational dynamics of 14‐3‐3ζ
2019 / Journal of Biological Chemistry
Many Gram-negative bacteria use type III secretion systems (T3SSs) to inject virulence effector proteins into eukaryotic cells. The T3SS apparatus… Continue reading The cytoplasmic domain of MxiG interacts with MxiK and directs assembly of the sorting platform in the Shigella type III secretion system
2019 / Journal of Molecular Recognition
Maltol is a flavor additive that is widely used in the daily diet of humans, and its biosafety attention is… Continue reading Binding mechanism of maltol with catalase investigated by spectroscopy, molecular docking, and enzyme activity assay
2019 / Bioorganic Chemistry
New tailored copper(II)–based intercalating complexes [Cu(L1)2] (1) and [Cu(L2)2] (2) were synthesized from Schiff base scaffold HL1 and HL2(E)-4-(2-((2-hydroxy-3-methoxybenzylidene)amino)ethyl)benzenesulfonamide and (E)-4-(2-((2-hydroxybenzylidene)amino)ethyl)benzenesulfonamide, respectively. The structure elucidation of complexes 1 and 2 was carried… Continue reading Structure elucidation {spectroscopic, single crystal X-ray diffraction and computational DFT studies} of new tailored benzenesulfonamide derived Schiff base copper(II) intercalating complexes: Comprehensive biological profile {DNA binding, pBR322 DNA cleavage, Topo I inhibition and cytotoxic activity}
2020 / European Journal of Medicinal Chemistry
Lung cancer is one of the most malignant tumors with the highest morbidity and mortality. Most of them are non-small… Continue reading Selective apoptosis-inducing activity of synthetic hydrocarbon-stapled SOS1 helix with d-amino acids in H358 cancer cells expressing KRASG12C
2019 / Bioorganic Chemistry
Four new isobenzofuranone monomers, (+)-epicoccone C ((+)-1), (-)-epicoccone C ((-)-1), epicoccone D (2), epicoccone E (3) and one new isobenzofuranone… Continue reading Isobenzofuranone monomer and dimer derivatives from the mangrove endophytic fungus Epicoccum nigrum SCNU-F0002 possess α-glucosidase inhibitory and antioxidant activity
2020 / Journal of Molecular Structure
The synthesis and conformational preferences of a novel chiral macrocyclic polyimine possessing spiro carbon atoms is described. The key feature… Continue reading Axial chirality inversion at a spiro carbon leads to efficient synthesis of polyimine macrocycle
2019 / The Journal of Physical Chemistry B
Conformational equilibria in the protein denatured state have key roles regulating folding, stability, and function. The extent of conformational bias… Continue reading Impact of Heat on Coil Hydrodynamic Size Yields the Energetics of Denatured State Conformational Bias
2020 / Colloids and Surfaces B: Biointerfaces
This manuscript presents a novel bioanalytical approach for the selective ratiometric fluorescent sensing of enzymatic activity of the alkaline phosphatase… Continue reading Mimicking biological process to detect alkaline phosphatase activity using the vitamin B6 cofactor conjugated bovine serum albumin capped CdS quantum dots
2019 / Journal of Natural Products
An ethanolic extract of Anneslea fragrans leaves showed potent preferential cytotoxicity against PANC-1 human pancreatic cancer cells under a nutrient-deprived condition, with… Continue reading Chemical Constituents of Anneslea fragrans and Their Antiausterity Activity against the PANC-1 Human Pancreatic Cancer Cell Line
2019 / Macromolecules
Switching the macromolecular helicity of poly(phenylacetylene)s (PPAs) through external achiral stimuli provides convenient possibilities in designing smart chiral materials. Herein,… Continue reading Thermoresponsive Dendronized Poly(phenylacetylene)s Showing Tunable Helicity
2020 / Biomaterials
Supramolecular hydrogel delivery systems have attracted widely attention owing to incorporating various therapeutic agents in carriers to decrease unpredictable toxicities,… Continue reading Dual-functional guanosine-based hydrogel integrating localized delivery and anticancer activities for cancer therapy
2019 / biomolecules
Amyloids represent protein fibrils with a highly ordered spatial structure, which not only cause dozens of incurable human and animal… Continue reading [PDF] Two Novel Amyloid Proteins, RopA and RopB, from the Root Nodule Bacterium Rhizobium leguminosarum
2020 / Colloids and Surfaces A: Physicochemical and Engineering Aspects
The advantage of using Langmuir–Blodgett (LB) method in assembling thin films is mainly the effective controlling the orientation of the… Continue reading Pyrene-based amphiphile regulated C60 aggregation in monolayers and Langmuir–Blodgett films
2019 / Nano Letters
Organic chiral materials have brought attention due to their potential application in the area of spin-optics and optoelectronics. Compared with… Continue reading Spin–Photon Coupling in Organic Chiral Crystals
2019 / Scientific Reports
We have studied the excited-state dynamics for the i-motif form of cytosine chains (dC)10, using the ultrafast fluorescence up-conversion technique.… Continue reading Exciton Absorption and Luminescence in i-Motif DNA
2019 / Journal of Biological Chemistry
Bacillus subtilis PdaC (BsPdaC) is a membrane-bound, multidomain peptidoglycan N-deacetylase acting on N-acetylmuramic (Mur-NAc) residues and conferring lysozyme resistance to… Continue reading Structure-function relationships underlying the dual N-acetylmuramic and N-acetylglucosamine specificities of the bacterial peptidoglycan deacetylase PdaC
