2020 / LWT
Ovalbumin (OVA) is widely used in the food industry due to its good emulsifying properties. However, polyphenols and polysaccharides in… Continue reading Influence of carboxymethylcellulose on the interaction between ovalbumin and tannic acid via noncovalent bonds and its effects on emulsifying properties
2019 / Chemical Science
RNA G-quadruplexes (rG4s) are emerging structural motifs that are of pivotal importance in chemistry and biology; however, the current structural… Continue reading Structural analysis and cellular visualization of APP RNA G-quadruplex
2019 / Biotechnology Reports
Xylanases decrease the xylan content in pretreated biomass releasing it from hemicellulose, thus improving the accessibility of cellulose for cellulases.… Continue reading Heterologous expression and functional characterization of a GH10 endoxylanase from Aspergillus fumigatus var. niveus with potential biotechnological application
2019 / Journal of Functional Foods
The inhibitory mechanism of chlorogenic acid (CHA) against porcine pancreatic α-amylase (PPA) was examined by enzyme kinetic analysis, circular dichroism,… Continue reading Inhibition of porcine pancreatic α-amylase activity by chlorogenic acid
2020 / Dyes and Pigments
In this paper, two axial chiral binaphthalene-diketopyrrolopyrrole dyads were developed as far-red to near-infrared circularly polarized luminescent materials. The dyads… Continue reading Axial chiral binaphthalene-diketopyrrolopyrrole dyads as efficient far-red to near-infrared circularly polarized luminescent emitters
2020 / Analytical Biochemistry
Among the biological approaches to therapeutics, are the cells, such as CAR-T cells engineered or not, the antibodies armed or… Continue reading VHH characterization.Recombinant VHHs: Production, characterization and affinity
2019 / Scientific Reports
Some lung and ovarian tumors are connected to the loss of expression of SMARCA4 gene. In its promoter region, a… Continue reading A pH-dependent bolt involving cytosine bases located in the lateral loops of antiparallel G-quadruplex structures within the SMARCA4 gene promotor
2019 / International Journal of Biological Macromolecules
In human αB-crystallin (αB-Cry), the highly conserved residues arginine 69 (R69) and aspartate 109 (D109) are located within a critical… Continue reading Structural and functional characterization of D109H and R69C mutant versions of human αB-crystallin: the biochemical pathomechanism underlying cataract and myopathy development
2020 / Biochimica et Biophysica Acta (BBA) - General Subjects
M20 aminopeptidases, such as Peptidase T (PepT), are implicated in the hydrolysis of oligopeptides during the terminal stages of protein… Continue reading Mutations of key substrate binding residues of leishmanial peptidase T alter its functional and structural dynamics
2019 / Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
DNA stands as the primary purpose of many anticancer drugs and according to the performed research on this field, some… Continue reading A novel view of the separate and simultaneous binding effects of docetaxel and anastrozole with calf thymus DNA: Experimental and in silico approaches
2019 / Biochimica et Biophysica Acta (BBA) - Biomembranes
Deducing the molecular details of membrane protein folding has lately become an important area of research in biology. Using Ail,… Continue reading Reversible folding energetics of Yersinia Ail barrel reveals a hyperfluorescent intermediate
2019 / Scientific Reports
Single-domain antibodies (VHHs or nanobodies), developed from heavy chain-only antibodies of camelids, are gaining attention as next-generation therapeutic agents. Despite… Continue reading Structural and thermodynamic basis for the recognition of the substrate-binding cleft on hen egg lysozyme by a single-domain antibody
2019 / Biochimica et Biophysica Acta (BBA) - Biomembranes
A strategy that has been gaining increased application for the study of the conformation, dynamics, orientation, and physicochemical properties of… Continue reading A comparison of activity, toxicity, and conformation of tritrpticin and two TOAC-labeled analogues. Effects on the mechanism of action
2020 / Biochimica et Biophysica Acta (BBA) - General Subjects
L-Homocysteine (Hcy) is a non-proteinogenic α-amino acid synthesized from dietary methionine. In healthy humans, high Hcy levels are a risk… Continue reading S-Homocysteinylation effects on transthyretin: worsening of cardiomyopathy onset
2019 / Journal of Biological Chemistry
Riboswitches are a class of non-protein–coding RNAs that directly sense cellular metabolites to regulate gene expression. They are model systems… Continue reading Nucleobase mutants of a bacterial preQ1-II riboswitch that uncouple metabolite sensing from gene regulation
2019 / Biochimica et Biophysica Acta (BBA) - Biomembranes
Multi-spanning membrane proteins usually require solubilization to allow proper purification and characterization, which generally impairs their structural and functional integrity.… Continue reading Membrane matters: The impact of a nanodisc-bilayer or a detergent microenvironment on the properties of two eubacterial rhodopsins
2019 / ChemPlusChem
Copper(II) complexes of the N‐terminal peptide fragments of tau protein have been studied by potentiometric and various spectroscopic techniques (UV‐vis,… Continue reading Copper(II) Coordination Abilities of the Tau Protein’s N‐Terminus Peptide Fragments: A Combined Potentiometric, Spectroscopic and Mass Spectrometric Study
2019 / Carbon
Using biomass materials as exfoliating agents to produce graphene is a promising strategy due to their biocompatibility, reproducibility and sustainability.… Continue reading One-pot preparation of zwitterionic graphene nanosheets with exceptional redispersibility and its application in pickering emulsions
2019 / Scientific Reports
Piperlongumine (PPL) has presented a variety of important pharmacological activities. In recent pharmacokinetics studies in rats, this molecule reached 76.39%… Continue reading Details of the cooperative binding of piperlongumine with rat serum albumin obtained by spectroscopic and computational analyses
2020 / Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
Entamoeba histolytica infection is highly prevalent in developing countries across the globe. The ATP synthesis in this pathogen is solely dependent… Continue reading Biochemical and biophysical characterization of the smallest pyruvate kinase from Entamoeba histolytica
