2019 / Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Mimetic peptides are promising therapeutic agents for atherosclerosis prevention. A 10-residue class G* peptide from apolipoprotein J (apoJ), namely, D-[113–122]apoJ,… Continue reading Low-density lipoprotein aggregation is inhibited by apolipoprotein J-derived mimetic peptide D-[113–122]apoJ
2020 / Journal of Photochemistry and Photobiology B: Biology
As a molecular chaperone, β-casein is difficult to form amyloid fibrils under physiological conditions due to its chaperone activity. Heparan… Continue reading The effect of heparan sulfate on promoting amyloid fibril formation by β-casein and their binding research with multi-spectroscopic approaches
2019 / The Journal of Organic Chemistry
Natural light-harvesting complexes (LHCs) absorb a broad spectrum of sunlight using a collection of photosynthetic pigments whose spatial arrangement is… Continue reading Peptoid Helix Displaying Flavone and Porphyrin: Synthesis and Intramolecular Energy Transfer
2019 / Journal of Molecular Cell
Ezrin, a membrane-cytoskeleton linker protein, plays an essential role in cell polarity establishment, cell migration and division. Recent studies show… Continue reading Acetylation of ezrin regulates membrane-cytoskeletal interaction underlying CCL18-elicited cell migration
2019 / Langmuir
Particles with a superparamagnetic cobalt inner core, silica outer core, and covalently bound homopolypeptide shell were investigated under thermal and… Continue reading Organophilic, Superparamagnetic, and Reversibly Thermoresponsive Silica-Polypeptide Core–Shell Particles
2019 / Chemical Engineering Journal
Long sludge age (10 ~ 30 d) is prevalent in the operation of wastewater treatment plants of China, leading to big challenge to… Continue reading Sludge age impacted the distribution, occurrence state and structure of organic compounds in activated sludge and affected the anaerobic degradability
2019 / Scientific Reports
Immunotherapy has emerged as a promising and effective treatment for cancer. The frequently used immunotherapy agents are immune checkpoint inhibitors,… Continue reading Structural and In Vitro Functional Analyses of Novel Plant-Produced Anti-Human PD1 Antibody
2019 / Nature Communications
Nanoscale biological assemblies exemplified by exosomes, endosomes and capsids, play crucial roles in all living systems. Supraparticles (SP) from inorganic nanoparticles… Continue reading Single- and multi-component chiral supraparticles as modular enantioselective catalysts
2019 / Journal of Peptide Science
IsCT1‐NH2 is a cationic antimicrobial peptide isolated from the venom of the scorpion Opisthacanthus madagascariensis that has a tendency to… Continue reading IsCT‐based analogs intending better biological activity
2019 / Langmuir
Fibrillation of amyloid-β peptide (Aβ) is closely associated with the progression of Alzheimer’s disease (AD), and so inhibition of Aβ… Continue reading Mixed Carboxyl and Hydrophobic Dendrimer Surface Inhibits Amyloid-β Fibrillation: New Insight from the Generation Number Effect
2019 / New Journal of Chemistry
Hydrogels based on G-quadruplexes (G-hydrogels) were prepared using guanosine 5′-monophosphate disodium salt, GMP, with a hyperbranched poly(ethylenimine), PEI, containing abundant… Continue reading G-Quadruplex based hydrogels stabilized by a cationic polymer as an efficient adsorbent of picric acid
2019 / Biochemistry
Alzheimer’s disease (AD) is associated with self-assembly of amyloid β-protein (Aβ) into soluble oligomers. Of the two predominant Aβ alloforms,… Continue reading Insulin Inhibits Aβ42 Aggregation and Prevents Aβ42-Induced Membrane Disruption
2019 / Materials Research Express
Although carbon dots (CDs) have been widely applied in nanobiotechnology and biomedicine, few studies have evaluated the intrinsic self-bioactivities and… Continue reading Maltase and sucrase inhibitory activities and hypoglycemic effects of carbon dots derived from charred Fructus crataegi
2020 / European Journal of Pharmaceutical Sciences
The co-formulation of drugs is widely used for small molecules, e.g. fixed-dose-combinations of synergistic medicines in the treatment of infections,… Continue reading Overcoming challenges in co-formulation of proteins with contradicting stability profiles – EPO plus G-CSF
2019 / Journal of Natural Products
Three biogenetically related ent-sauchinone-type lignans (1–3), four 8-O-4′-type neolignans (4–7), a diaryldimethylbutane lignan (8), and a cyclic carbonate (9), along with… Continue reading Lignans from Saururus chinensis with Inhibitory Effects on Nitric Oxide Production
2019 / ACS Biomaterials Science & Engineering
Over the last decade, synthetically designed scaffolds are emerging as promising biomaterials for tissue engineering applications. In this context, peptide… Continue reading Designing a Tenascin-C-Inspired Short Bioactive Peptide Scaffold to Direct and Control Cellular Behavior
2019 / Molecular Immunology
Non-specific lipid transfer proteins (LTPs) are important allergens in fruits, pollen, vegetables, nuts and latex. Due to their compact structure,… Continue reading Boiling down the cysteine-stabilized LTP fold – loss of structural and immunological integrity of allergenic Art v 3 and Pru p 3 as a consequence of irreversible lanthionine formation
2019 / Cells
DNA lesions are formed continuously in each living cell as a result of environmental factors, ionisation radiation, metabolic processes, etc.… Continue reading The Influence of (5’R)- and (5’S)-5′,8-Cyclo-2′-Deoxyadenosine on UDG and hAPE1 Activity. Tandem Lesions are the Base Excision Repair System’s Nightmare.
2019 / ACS Omega
Synthetic peptides mimicking the binding site of fertilin β to its receptor, integrin α6β1, were shown to inhibit sperm–egg fusion… Continue reading Disorder-to-Order Markers of a Cyclic Hexapeptide Inspired from the Binding Site of Fertilin β Involved in Fertilization Process
2019 / Food Chemistry
The present study was aimed to investigate the effects of non-covalent and covalent interactions between soy protein isolate (SPI) and… Continue reading Effect of non-covalent and covalent complexation of (−)-epigallocatechin gallate with soybean protein isolate on protein structure and in vitro digestion characteristics
