2019 / Cellular and Molecular Life Sciences
Odorant-binding proteins (OBPs) are small soluble proteins that are thought to transport hydrophobic odorants across the aqueous sensillar lymph to… Continue reading The Drosophila odorant-binding protein 28a is involved in the detection of the floral odour ß-ionone
2019 / Macromolecular Research
Heterotypic collagen fibril has long been found in the tissues of organisms, which plays an important role in the formation… Continue reading Reconstituted Fibril from Heterogenic Collagens-A New Method to Regulate Properties of Collagen Gels
2019 / Nucleic Acids Research
The trinucleotide repeat expansion disorders (TREDs) constitute of a group of >40 hereditary neurodegenerative human diseases associated with abnormal expansion… Continue reading Structural insights into synthetic ligands targeting A–A pairs in disease-related CAG RNA repeats
2019 / Archives of Biochemistry and Biophysics
Methotrexate (MTX) is advised in the treatment of solid tumours, hematologic malignancies and autoimmune disorders. On reaching the circulation, 60%… Continue reading Understanding the binding interaction between methotrexate and human alpha-2-macroglobulin: Multi-spectroscopic and computational investigation
2019 / Fish and Shellfish Immunology
Photobacteriosis caused by Photobacterium damselae subsp. piscicida (Pdp) remains one of the main infectious diseases affecting cultured fish in Mediterranean countries. Diverse vaccine formulations… Continue reading Outer membrane protein FrpA, the siderophore piscibactin receptor of Photobacterium damselae subsp. piscicida, as a subunit vaccine against photobacteriosis in sole (Solea senegalensis)
2019 / Scientific Reports
TRPM8 is a member of the transient receptor potential ion channel family where it functions as a cold and pain… Continue reading Competitive Interactions between PIRT, the Cold Sensing Ion Channel TRPM8, and PIP2 Suggest a Mechanism for Regulation
2019 / Analytical Biochemistry
Proteins primarily absorb UV light due to the presence of tryptophan, tyrosine, and phenylalanine residues, with absorbance maxima at 280,… Continue reading A method to probe protein structure from UV absorbance spectra
2019 / biomolecules
Indole-3-acetic acid (IAA) is a major plant hormone that affects many cellular processes in plants, bacteria, yeast, and human cells… Continue reading New Insights into Structural and Functional Roles of Indole-3-acetic acid (IAA): Changes in DNA Topology and Gene Expression in Bacteria
2019 / Acta Biomaterialia
Glaucoma is a leading cause of irreversible blindness worldwide. Current treatments of glaucoma involve lowering the IOP by means of… Continue reading An injectable peptide hydrogel for reconstruction of the human trabecular meshwork
2019 / Ecotoxicology and Environmental Safety
Perfluorodecanoic acid (PFDA) has been widely used in production of many daily necessities because of its special nature. Althoughtoxic effects… Continue reading Perfluorodecanoic acid-induced oxidative stress and DNA damage investigated at the cellular and molecular levels
2019 / The Journal of Physical Chemistry B
Naturally occurring enzymatic pathways enable highly specific, rapid thiophenic sulfur cleavage occurring at ambient temperature and pressure, which may be… Continue reading Inhibition Mechanisms of Rhodococcus Erythropolis 2′-Hydroxybiphenyl-2-sulfinate Desulfinase (DszB)
2019 / ACS Applied Biomaterials
Herein we report for the first time the supramolecular hydrogelation of a derivative of 3-nitrotyrosine (3-NT), which is an oxidized… Continue reading Supramolecular Hydrogel from an Oxidized Byproduct of Tyrosine
2019 / Scientific Reports
Enzymatic gold nanoparticles (B-GNPs) have been synthesized using a natural anticancer agent bromelain (a cysteine protease) and these nanoparticles were… Continue reading Cisplatin bioconjugated enzymatic GNPs amplify the effect of cisplatin with acquiescence
2019 / Biochemical Journal
HAX-1, a multifunctional protein involved in cell proliferation, calcium homeostasis, and regulation of apoptosis, is a promising therapeutic target. It… Continue reading Structural modeling and role of HAX-1 as a positive allosteric modulator of human serine protease HtrA2
2019 / Biophysical Journal
Coat protein (COP) I and COP II complexes are involved in the transport of proteins between the endoplasmic reticulum and… Continue reading Lipid Binding Controls Dimerization of the Coat Protein p24 Transmembrane Helix
2019 / Biophysical Journal
Stress-induced unfolding and fibrillation of insulin represent serious medical and biotechnological problems. Despite many attempts to elucidate the molecular mechanisms… Continue reading Modulating Insulin Fibrillation Using Engineered B-Chains with Mutated C-Termini
2019 / Colloids and Surfaces B: Biointerfaces
To investigate the interaction between bovine serum albumin (BSA) and silver nanoparticles (AgNPs) at five different pHs (below (3.0 and… Continue reading Influence of pH on interaction of silver nanoparticles – protein: Analyses by spectroscopic and thermodynamic ideology
2019 / plos one
Dengue virus (DENV) nonstructural 1 (NS1) protein is a specific and sensitive biomarker for the diagnosis of dengue. In this… Continue reading Development of peptide biosensor for the detection of dengue fever biomarker, nonstructural 1
2019 / Bioconjugate Chemistry
Treatment of ocular diseases associated with neovascularization currently requires frequent intravitreal injections of antivascular endothelial growth factor (anti-VEGF) therapies. Reducing… Continue reading Hyaluronic Acid–Antibody Fragment Bioconjugates for Extended Ocular Pharmacokinetics
2019 / Journal of Biological Chemistry
α-Linked GalNAc (α-GalNAc) is most notably found at the nonreducing terminus of the blood type–determining A-antigen and as the initial… Continue reading Prospecting for microbial α-N-acetylgalactosaminidases yields a new class of GH31 O-glycanase
