Methane generation via intraprotein C–S bond cleavage in cytochrome b562 reconstituted with nickel didehydrocorrin

2019 / Journal of Organometallic Chemistry

Cytochrome b562 (Cyt b562) reconstituted with nickel didehydrocorrin (NiII(DDHC)), a protein-based functional model of methyl-coenzyme M reductase (MCR), was investigated to demonstrate methane… Continue reading Methane generation via intraprotein C–S bond cleavage in cytochrome b562 reconstituted with nickel didehydrocorrin

Heather Haffner

A Thermostable Three-Dimensional Homochiral Metal–Organic Framework Constructed from N-Rich Ligand: Syntheses, Crystal Structures, and Properties

2019 / Journal of Inorganic and Organometallic Polymers and Materials

By using the designed N-rich 3,6-bis(4-methyl-1H-imidazol-1-yl)pyridazine (b4mmp) and chiral d-camphoric acid (d-cam) ligands to react with cadmium acetate, a new bulk… Continue reading A Thermostable Three-Dimensional Homochiral Metal–Organic Framework Constructed from N-Rich Ligand: Syntheses, Crystal Structures, and Properties

Heather Haffner

Structure of full-length wild-type human phenylalanine hydroxylase by small angle X-ray scattering reveals substrate-induced conformational stability

2019 / Scientific Reports

Human phenylalanine hydroxylase (hPAH) hydroxylates L-phenylalanine (L-Phe) to L-tyrosine, a precursor for neurotransmitter biosynthesis. Phenylketonuria (PKU), caused by mutations in PAH that impair PAH… Continue reading Structure of full-length wild-type human phenylalanine hydroxylase by small angle X-ray scattering reveals substrate-induced conformational stability

Heather Haffner

Mutational Analysis of a Highly Conserved PLSSMXP Sequence in the Small Subunit of Bacillus licheniformis γ-Glutamyltranspeptidase

2019 / biomolecules

A highly conserved 458PLSSMXP464 sequence in the small subunit (S-subunit) of an industrially important Bacillus licheniformis γ-glutamyltranspeptidase (BlGGT) was identified by sequence alignment. Molecular… Continue reading Mutational Analysis of a Highly Conserved PLSSMXP Sequence in the Small Subunit of Bacillus licheniformis γ-Glutamyltranspeptidase

Heather Haffner

Copper(ii) complexes based on levofloxacin and 2N-donor ligands: synthesis, crystal structures and in vitro biological evaluation

2019 / New Journal of Chemistry

Herein, we report the synthesis, molecular structures and bioevaluation of two different cationic copper(II) complexes with the third generation quinolone… Continue reading Copper(ii) complexes based on levofloxacin and 2N-donor ligands: synthesis, crystal structures and in vitro biological evaluation

Heather Haffner