Thermodynamics, molecular modelling and denaturation studies on exploring the binding mechanism of tetramethylpyrazine with human serum albumin

2020 / The Journal of Chemical Thermodynamics

Tetramethylpyrazine (TMPZ), a Chinese herb effectively used for cardiovascular disorders. The present study reports in vitro interaction studies of TMPZ with human… Continue reading Thermodynamics, molecular modelling and denaturation studies on exploring the binding mechanism of tetramethylpyrazine with human serum albumin

Heather Haffner

Botryane terpenoids produced by Nemania bipapillata, an endophytic fungus isolated from red alga Asparagopsis taxiformis – Falkenbergia stage

2020 / Scientific Reports

A chemical study of the EtOAc extract of Nemania bipapillata (AT-05), an endophytic fungus isolated from the marine red alga Asparagopsis taxiformis – Falkenbergia stage, led… Continue reading Botryane terpenoids produced by Nemania bipapillata, an endophytic fungus isolated from red alga Asparagopsis taxiformis – Falkenbergia stage

Heather Haffner

Reduced Renal Colonization and Enhanced Protection by Leptospiral Factor H Binding Proteins as a Multisubunit Vaccine Against Leptospirosis in Hamsters

2019 / Vaccines

Subunit vaccines conferring complete protection against leptospirosis are not currently available. The interactions of factor H binding proteins (FHBPs) on… Continue reading Reduced Renal Colonization and Enhanced Protection by Leptospiral Factor H Binding Proteins as a Multisubunit Vaccine Against Leptospirosis in Hamsters

Heather Haffner

Multiple spectroscopic and theoretical investigation of meso-tetra-(4-pyridyl)porphyrin‑ruthenium(II) complexes in HSA-binding studies. Effect of Zn(II) in protein binding

2020 / Journal of Molecular Liquids

The present work reports the interaction between human serum albumin (HSA) – the main bio-distributor of exogenous and endogenous compounds… Continue reading Multiple spectroscopic and theoretical investigation of meso-tetra-(4-pyridyl)porphyrin‑ruthenium(II) complexes in HSA-binding studies. Effect of Zn(II) in protein binding

Heather Haffner

Structural characterization of transfection nanosystems based on tricationic surfactants and short double stranded oligonucleotides

2019 / Biochemical and Biophysical Research Communications

For several years cationic surfactants have been the subjects of extensive studies as potential transgene carriers to be used in… Continue reading Structural characterization of transfection nanosystems based on tricationic surfactants and short double stranded oligonucleotides

Heather Haffner

Enhanced paracellular delivery of vaccine by hydrogel microparticles-mediated reversible tight junction opening for effective oral immunization

2019 / Journal of Controlled Release

The current conventional injectable vaccines face several drawbacks such as inconvenience and ineffectiveness in mucosal immunization. Therefore, the current development… Continue reading Enhanced paracellular delivery of vaccine by hydrogel microparticles-mediated reversible tight junction opening for effective oral immunization

Heather Haffner

Structural differences of commercial and recombinant lipase B from Candida antarctica: An important implication on enzymes thermostability

2019 / International Journal of Biological Macromolecules

Lipase B from Candida antarctica (CalB) is the most widely used lipase, including in many industrial sectors, such as in biodiesel and… Continue reading Structural differences of commercial and recombinant lipase B from Candida antarctica: An important implication on enzymes thermostability

Heather Haffner