Alternative Assembly of α-Synuclein Leading to Protein Film Formation and Its Application for Developing Polydiacetylene-Based Sensing Materials

2019 / Langmuir

Understanding the self-assembly process of amyloidogenic protein is valuable not only to find its pathological implication but also to prepare… Continue reading Alternative Assembly of α-Synuclein Leading to Protein Film Formation and Its Application for Developing Polydiacetylene-Based Sensing Materials

Heather Haffner

Targeting multiple G-quadruplex–forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives

2019 / European Journal of Medicinal Chemistry

It is well recognized that the non-canonical DNA structures known as G-quadruplexes (G4s) have a potential anticancer significance and several… Continue reading Targeting multiple G-quadruplex–forming DNA sequences: Design, biophysical and biological evaluations of indolo-naphthyridine scaffold derivatives

Heather Haffner

Rapid biofilm eradication of the antimicrobial peptide 1018-K6 against Staphylococcus aureus: A new potential tool to fight bacterial biofilms

2020 / Food Control

Staphylococcal food poisoning – caused by certain enterotoxigenic staphylococci – is one of the most common worldwide foodborne diseases. In… Continue reading Rapid biofilm eradication of the antimicrobial peptide 1018-K6 against Staphylococcus aureus: A new potential tool to fight bacterial biofilms

Heather Haffner

Intrinsically disordered HAX-1 regulates Ca2+ cycling by interacting with lipid membranes and the phospholamban cytoplasmic region☆

2019 / Biochimica et Biophysica Acta (BBA) - Biomembranes

Hematopoietic-substrate-1 associated protein X-1 (HAX-1) is a 279 amino acid protein expressed ubiquitously. In cardiac muscle, HAX-1 was found to… Continue reading Intrinsically disordered HAX-1 regulates Ca2+ cycling by interacting with lipid membranes and the phospholamban cytoplasmic region☆

Heather Haffner

Physiologically relevant reconstitution of iron-sulfur cluster biosynthesis uncovers persulfide-processing functions of ferredoxin-2 and frataxin

2019 / Nature Communications

Iron-sulfur (Fe-S) clusters are essential protein cofactors whose biosynthetic defects lead to severe diseases among which is Friedreich’s ataxia caused… Continue reading Physiologically relevant reconstitution of iron-sulfur cluster biosynthesis uncovers persulfide-processing functions of ferredoxin-2 and frataxin

Heather Haffner

Chiral superstructures from homochiral Zn2+, Co2+, Fe2+‐2,6‐bis (aryl ethylimine)pyridine complexes

2019 / Chirality

We report the hierarchical supramolecular organization of metallosupramolecular homochiral complexes 1‐Λ‐(S,S,S,S)‐M2+/1‐∆‐(R,R,R,R)‐M2+ and 2‐ Λ‐(S,S,S,S)‐M2+/2‐∆‐ (R,R,R,R)‐M2+ of M2+ = Co2+, Fe2+, Zn2+ metal ions with chiral pseudo‐terpyridine‐type… Continue reading Chiral superstructures from homochiral Zn2+, Co2+, Fe2+‐2,6‐bis (aryl ethylimine)pyridine complexes

Heather Haffner

Homodinuclear lanthanoid(III) dithiocarbamato complexes bridged by 2,2′-bipyrimidine: Syntheses, structures and spectroscopic properties

2019 / Polyhedron

Four new homodinuclear lanthanoid(III) dithiocarbamato (RR′dtc−) complexes bridged by 2,2′-bipyrimidine (bpm) of the form [{Ln(RR′dtc)3}2(µ-bpm)] {Ln = Nd or Eu; RR′ = dimethyl- (Me2) or… Continue reading Homodinuclear lanthanoid(III) dithiocarbamato complexes bridged by 2,2′-bipyrimidine: Syntheses, structures and spectroscopic properties

Heather Haffner