Circular Dichroism Archives

Interaction of a sphingolipid with human serum albumin in the native, thermally denatured and chemically denatured states: Emission wavelength-dependent photophysical revelation

2019 / Journal of Molecular Liquids

The present study exhibits a spectroscopic deciphering of the effect of a phosphosphingolipid, sphingomyelin (SM), on native as well as… Continue reading Interaction of a sphingolipid with human serum albumin in the native, thermally denatured and chemically denatured states: Emission wavelength-dependent photophysical revelation

Blue autofluorescence in protein aggregates “lighted on” by UV induced oxidation

2019 / Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Oxidation of amino acid side chains in protein structure can be induced by UV irradiation leading to critical changes in… Continue reading Blue autofluorescence in protein aggregates “lighted on” by UV induced oxidation

Enhancement of the Photofunction of Phosphorescent Pt(II) Cyclometalated Complexes Driven by Substituents: Solid-State Luminescence and Circularly Polarized Luminescence

2019 / Journal of Organic Chemistry

Ligand functionalization is an attractive strategy for enhancing the performance of metal-based phosphorescent emitters. Here, we report the synthesis and… Continue reading Enhancement of the Photofunction of Phosphorescent Pt(II) Cyclometalated Complexes Driven by Substituents: Solid-State Luminescence and Circularly Polarized Luminescence

Covalently-assembled single-chain protein nanostructures with ultra-high stability

2019 / Nature Communications

Protein nanostructures with precisely defined geometries have many potential applications in catalysis, sensing, signal processing, and drug delivery. While many… Continue reading Covalently-assembled single-chain protein nanostructures with ultra-high stability

Aggregation-induced red shift in N,S-doped chiral carbon dot emissions for moisture sensing

2019 / New Journal of Chemistry

Being a promising class of carbogenic nanomaterials with excellent photophysical and photochemical properties, carbon dots (Cdots) have been exploited for… Continue reading Aggregation-induced red shift in N,S-doped chiral carbon dot emissions for moisture sensing

G37V mutation of Aβ42 induces a nontoxic ellipse-like aggregate: An in vitro and in silico study

2019 / Neurochemistry International

The glycine zipper motif at the C-terminus of the β-amyloid (Aβ) peptide have been shown to strongly influence the formation… Continue reading G37V mutation of Aβ42 induces a nontoxic ellipse-like aggregate: An in vitro and in silico study

Effects of membrane lipid composition on Mycobacterium tuberculosis EsxA membrane insertion: A dual play of fluidity and charge

2019 / Tuberculosis

As a key virulence factor of Mycobacterium tuberculosis, EsxA or 6-kDa early secreted antigenic target (ESAT-6) has been implicated in phagosome… Continue reading Effects of membrane lipid composition on Mycobacterium tuberculosis EsxA membrane insertion: A dual play of fluidity and charge

Conformation change of α-synuclein(61－95) at the air-water interface and quantitative measurement of the tilt angle of the axis of its α-helix by multiple angle incidence resolution spectroscopy

2019 / Colloids and Surfaces B: Biointerfaces

Various techniques have been developed to determine protein’s structure to understand how proteins work.  Compared with X-ray crystallography requiring proteins to… Continue reading Conformation change of α-synuclein(61－95) at the air-water interface and quantitative measurement of the tilt angle of the axis of its α-helix by multiple angle incidence resolution spectroscopy

Controlled release of lysozyme based core/shells structured alginate beads with CaCO3 microparticles using Pickering emulsion template and in situ gelation

2019 / Colloids and Surfaces B: Biointerfaces

To employ dual advantages of emulsion and gel, a facile approach was investigated to fabricate core/shells structured hydrogel beads based… Continue reading Controlled release of lysozyme based core/shells structured alginate beads with CaCO3 microparticles using Pickering emulsion template and in situ gelation

Tannic acid as a precipitating agent of human plasma proteins

2019 / European Journal of Pharmaceutical Sciences

The search for plasma proteins precipitation methods has been increasing due to the plasma protein therapeutic needs in world-wide. Thus,… Continue reading Tannic acid as a precipitating agent of human plasma proteins

Characterization of the full‐length human Grb7 protein and a phosphorylation representative mutant

2019 / Journal of Molecular Recognition

It is well known the dimerization state of receptor tyrosine kinases (RTKs), in conjunction with binding partners such as the… Continue reading Characterization of the full‐length human Grb7 protein and a phosphorylation representative mutant

Mechanism of action of antimicrobial peptide P5 truncations against Pseudomonas aeruginosa and Staphylococcus aureus

2019 / AMB Express

Rates of microbial drug resistance are increasing worldwide; therefore, antimicrobial peptides (AMPs) are considered promising alternative therapeutic agents to antibiotics.… Continue reading Mechanism of action of antimicrobial peptide P5 truncations against Pseudomonas aeruginosa and Staphylococcus aureus

Anti-inflammatory spiroaxane and drimane sesquiterpenoids from Talaromyces minioluteus (Penicillium minioluteum)

2019 / Bioorganic Chemistry

A new spiroaxane sesquiterpenoid talaminoid A (1) and two drimane sesquiterpenoid talaminoids B and C (2 and 3), together with four known… Continue reading Anti-inflammatory spiroaxane and drimane sesquiterpenoids from Talaromyces minioluteus (Penicillium minioluteum)

Development of a Self‐Assembled Peptide/Methylcellulose‐Based Bioink for 3D Bioprinting

2019 / Macromolecular Materials and Engineering

The introduction of 3D bioprinting to fabricate living constructs with tailored architecture has provided a new paradigm for biofabrication, with… Continue reading Development of a Self‐Assembled Peptide/Methylcellulose‐Based Bioink for 3D Bioprinting

Biophysical and biochemical characterization of a thermostable archaeal cyclophilin from Methanobrevibacter ruminantium

2019 / International Journal of Biological Macromolecules

The archaeal protein folding machinery is quite similar to that found in eukaryotes, especially in terms of shared components like… Continue reading Biophysical and biochemical characterization of a thermostable archaeal cyclophilin from Methanobrevibacter ruminantium

Aspartic protease from Aspergillus niger: Molecular characterization and interaction with pepstatin A

2019 / International Journal of Biological Macromolecules

In the pursuit of industrial aspartic proteases, aspergillopepsin A-like endopeptidase from the fungi Aspergillus niger, was identified and cultured by solid… Continue reading Aspartic protease from Aspergillus niger: Molecular characterization and interaction with pepstatin A

Phenol‐Soluble‐Modulin‐Inspired Amphipathic Peptides Have Bactericidal Activity against Multidrug‐Resistant Bacteria

2019 / ChemMedChem

Phenol‐soluble modulins (PSMs) are a large family of cytolytic peptide toxins produced by Staphylococcus aureus. Based on their amino acid sequences,… Continue reading Phenol‐Soluble‐Modulin‐Inspired Amphipathic Peptides Have Bactericidal Activity against Multidrug‐Resistant Bacteria

Effects of molecular crowding environment on the acquisition of toxic properties of wild-type SOD1

2019 / Biochimica et Biophysica Acta (BBA) - General Subjects

Mutants of Cu,Zn-superoxide dismutase (SOD1) exhibit cytotoxicity such as aggregation and pro-oxidation after denaturation, which is thought to be involved… Continue reading Effects of molecular crowding environment on the acquisition of toxic properties of wild-type SOD1

Biochemical characterization of human D-2-hydroxyglutarate dehydrogenase and two disease related variants reveals the molecular cause of D-2-hydroxyglutaric aciduria

2019 / Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

D-2-hydroxyglutaric aciduria is a neurometabolic disorder, characterized by the accumulation of D-2-hydroxyglutarate (D-2HG) in human mitochondria. Increased levels of D-2HG… Continue reading Biochemical characterization of human D-2-hydroxyglutarate dehydrogenase and two disease related variants reveals the molecular cause of D-2-hydroxyglutaric aciduria

Binding and photodynamic action of the cationic zinc phthalocyanines with different types of DNA toward understanding of their cancer therapy activity

2019 / Journal of Inorganic Biochemistry

Two cationic zinc phthalocyanines have been tested for their interactions with several DNA secondary structures. Despite different aggregation properties, both… Continue reading Binding and photodynamic action of the cationic zinc phthalocyanines with different types of DNA toward understanding of their cancer therapy activity

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