A physicochemical investigation on the metal binding properties of TtSmtB, a thermophilic member of the ArsR/SmtB transcription factor family

2019 / International Journal of Biological Macromolecules

The transcription factors of the ArsR/SmtB family are widespread within the bacterial and archaeal kingdoms. They are transcriptional repressors able… Continue reading A physicochemical investigation on the metal binding properties of TtSmtB, a thermophilic member of the ArsR/SmtB transcription factor family

Heather Haffner

Characterization of methylglyoxal induced advanced glycation end products and aggregates of human transferrin: Biophysical and microscopic insight

2019 / International Journal of Biological Macromolecules

Protein aggregation and glycation is gaining increased attention in recent times as protein aggregates and advanced glycation end products (AGEs)… Continue reading Characterization of methylglyoxal induced advanced glycation end products and aggregates of human transferrin: Biophysical and microscopic insight

Heather Haffner

Structural studies on the individual domains of human γS-crystallin and its G57W mutant unfolds mechanistic insights into childhood cataracts

2019 / Biochemical and Biophysical Research Communications

Inter-domain interactions tune the exceptional stability of human γS-crystallin (γS-WT) in the eye lens, which lasts a lifetime with no… Continue reading Structural studies on the individual domains of human γS-crystallin and its G57W mutant unfolds mechanistic insights into childhood cataracts

Heather Haffner

Insight into the interaction of benzothiazole tethered triazole analogues with human serum albumin: Spectroscopy and molecular docking approaches

2019 / Luminescence

The interaction of four benzothiazole tethered triazole analogues (MS43, MS70, MS71, and MS78) with human serum albumin (HSA) was investigated… Continue reading Insight into the interaction of benzothiazole tethered triazole analogues with human serum albumin: Spectroscopy and molecular docking approaches

Heather Haffner

A novel enantioselective SGNH family esterase (NmSGNH1) from Neisseria meningitides: Characterization, mutational analysis, and ester synthesis

2019 / Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

In Neisseria sp., SGNH family esterases are involved in bacterial pathogenesis as well as cell wall peptidoglycan maturation. Here, a novel enantioselective… Continue reading A novel enantioselective SGNH family esterase (NmSGNH1) from Neisseria meningitides: Characterization, mutational analysis, and ester synthesis

Heather Haffner

Application of high-pressure homogenization for improving the physicochemical, functional and rheological properties of myofibrillar protein

2019 / International Journal of Biological Macromolecules

The present work investigated effects of high-pressure homogenization (HPH) pressure (0, 40, 80 and 120 MPa) on physicochemical, functional and rheological… Continue reading Application of high-pressure homogenization for improving the physicochemical, functional and rheological properties of myofibrillar protein

Heather Haffner