Pheromone peptides are an important component of bacterial quorum‐sensing system. The pheromone peptide cOB1 (VAVLVLGA) of native commensal Enterococcus faecalis has also… Continue reading Pheromone peptide cOB1 from native Enterococcus faecalis forms amyloid‐like structures: A new paradigm for peptide pheromones
Heather Haffner
November 13, 2019
Eight porphyrin dimers with various functional bridging blocks and chiral amide-bonds were synthesized and characterized. An analysis of the spectroscopy… Continue reading Synthesis and properties of chiral amide-bonded porphyrin dimers with various functional bridging blocks
Heather Haffner
November 13, 2019
Worldwide, more than one-third of the population suffers from allergies. A significant fraction of officially registered allergens originate from the… Continue reading Comparative structural and thermal stability studies of Cuc m 2.0101, Art v 4.0101 and other allergenic profilins
Heather Haffner
November 13, 2019
The interaction between gold sub-nanometer clusters composed of ten atoms (Au10) and tetrakis(4-sulfonatophenyl)porphyrin (TPPS) was investigated through various spectroscopic techniques.… Continue reading Dimeric Pyranonaphthoquinone Glycosides with Anti-HIV and Cytotoxic Activities from a Soil-Derived Streptomyces
Heather Haffner
November 13, 2019
The scalp-ear-nipple (SEN) syndrome is an autosomal-dominant disorder characterized by cutis aplasia of the scalp and malformations of breast, external… Continue reading Molecular basis of the scalp-ear-nipple syndrome unraveled by the characterization of disease-causing KCTD1 mutants
Heather Haffner
November 13, 2019
The neurodegenerative disease Friedreich ataxia results from a deficiency of frataxin, a mitochondrial protein. Most patients have a GAA expansion… Continue reading Exploring iron-binding to human frataxin and to selected Friedreich ataxia mutants by means of NMR and EPR spectroscopies
Heather Haffner
November 13, 2019
Heather Haffner
November 13, 2019
Block and random copolymers are synthesized by the copolymerization of N‐tert‐butoxycarbonyl‐ʟ‐valine 4‐ethynylanilide (1L) and N‐tert‐butoxycarbonyl‐d‐valine 4‐ethynylanilide (1D) using [(nbd)Rh{C(Ph) = CPh2}(PPh3)]/PPh3 as a… Continue reading Polymerization of Substituted Acetylenes Using Well‐Defined Rhodium Complex Catalyst. Chirality Transfer and Amplification in Chiral‐Chiral Block and Random Copolymers
Heather Haffner
November 13, 2019
Cold plasma is an emerging technology increasingly applied in the agri-food industry. For fruit and vegetables, enzymatic browning is a… Continue reading Changes in activity, structure and morphology of horseradish peroxidase induced by cold plasma
Heather Haffner
November 13, 2019
Five new compounds (1–5), including three hexalactone derivatives (1–3) and a pair of new oxaspiro-carbon epimeric glycosides (4 and 5), and six… Continue reading New hexalactone derivatives and a pair of new oxaspiro-carbon epimeric glycosides from the fruits of Illicium lanceolatum
Heather Haffner
November 13, 2019
FAD synthase, the last enzyme of the pathway converting riboflavin to FAD, exists in humans in different isoforms, with isoforms… Continue reading The hidden side of the human FAD synthase 2
Heather Haffner
November 13, 2019
Heather Haffner
November 13, 2019
Hypoxanthine riboside (HXR) is a nucleoside essential for wobble base pairs to translate the genetic code. In this work, an… Continue reading Spectroscopic and computational exploration of hypoxanthine riboside interacting with plasma albumin
Heather Haffner
November 13, 2019
The prototypical kinase c-Src plays an important role in numerous signal transduction pathways, where its activity is tightly regulated by… Continue reading Autophosphorylation activates c-Src kinase through global structural rearrangements
Heather Haffner
November 13, 2019
Many microbial rhodopsins self-oligomerize, but the functional consequences of oligomerization have not been well clarified. We examined the effects of… Continue reading Functional importance of the oligomer formation of the cyanobacterial H+ pump Gloeobacter rhodopsin
Heather Haffner
November 13, 2019
Cyclodextrins are very important excipients in the pharmaceutical industry. Given the multitude of native and semisynthetic cyclodextrin derivatives, there is… Continue reading Simple circular dichroism method for selection of the optimal cyclodextrin for drug complexation
Heather Haffner
November 13, 2019
Chiral self‐assembly of peptides is of fundamental interest in the field of biology and material science. Protamine, an alkaline biomacromolecule… Continue reading Protamine‐induced condensation of peptide nanofilaments into twisted bundles with controlled helical geometry
Heather Haffner
November 13, 2019
The DNA/RNA-binding KIN protein was discovered in 1989, and since then, it has been found to participate in several processes,… Continue reading Biophysical characterization and molecular phylogeny of human KIN protein
Heather Haffner
November 13, 2019
Chitin deacetylase, an enzyme isolated from Cryptococcus laurentii RY1, catalyzes the hydrolysis of acetamido group of N-acetyl-D-glucosamine unit of chitin. The primary objective… Continue reading DMSO strengthens chitin deacetylase-chitin interaction: Physicochemical, kinetic, structural and catalytic insights
Heather Haffner
November 13, 2019
The present study is focused on the binding interaction of sulfadoxine with bovine serum albumin under simulated physiological conditions using spectrofluorimetry. Various… Continue reading Spectral and molecular modelling studies of sulfadoxine interaction with bovine serum albumin
Heather Haffner
November 13, 2019