The human TRA2B gene consists of 10 exons and 9 introns and produces 5 splice isoforms (TRA2β1 to TRA2β5). TRA2B exon 2 encodes multiple premature termination… Continue reading HnRNPA1 interacts with G-quadruplex in the TRA2B promoter and stimulates its transcription in human colon cancer cells
Heather Haffner
November 13, 2019
In this work novel magnetic cationic liposomal nanoformulations were synthesized for the encapsulation of a crystallographically defined ternary V(IV)-curcumin-bipyridine (VCur)… Continue reading Magnetic cationic liposomal nanocarriers for the efficient drug delivery of a curcumin-based vanadium complex with anticancer potential
Heather Haffner
November 13, 2019
Peroxiredoxins (Prx) are enzymes that efficiently reduce hydroperoxides through active participation of cysteine residues (CP, CR). The first step in… Continue reading Unraveling the effects of peroxiredoxin 2 nitration; role of C-terminal tyrosine 193
Heather Haffner
November 13, 2019
Gallic acid is a naturally occurring plant polyphenol found in green tea and various fruits. Under certain conditions gallic acid… Continue reading Inactivation of Alpha-2-Macroglobulin by Photo-Illuminated Gallic Acid
Heather Haffner
November 13, 2019
Lonimacranaldes A and B (1 and 2), along with one biogenetically related intermediate, lonimacranalde C (3), were isolated from the flower buds… Continue reading Lonimacranaldes A–C, three iridoids with novel skeletons from Lonicera macranthoides
Heather Haffner
November 13, 2019
Heather Haffner
November 13, 2019
Chemiluminescent (CL) reagent N-(4-aminobutyl)-N-ethylisoluminol (ABEI)-functionalized CaCO3 microspheres with a dual catalytic system consisting of Co2+ and horseradish peroxidase (HRP) (HRP/ABEI/Co2+-CaCO3 MPs) were synthesized via… Continue reading Combined Transition-Metal/Enzyme Dual Catalytic System for Highly Intensive Glow-Type Chemiluminescence-Functionalized CaCO3 Microspheres
Heather Haffner
November 13, 2019
Obtaining the stable dispersion of single-walled carbon nanotubes is vital for realizing their practical applications. In our work, soy protein… Continue reading The effect of the secondary structures of proteins on dispersing SWNTs
Heather Haffner
November 13, 2019
Nucleic acid aptamers have emerged as an attractive class of carrier molecules due to their ability to bind with high… Continue reading RNA G-quadruplex as supramolecular carrier for cancer-selective delivery
Heather Haffner
November 13, 2019
Qualitative and quantitative understanding of partially folded states of protein is essential in gaining deeper insights into folding pathways. We… Continue reading Alkali induced unique partially folded state of bovine serum albumin: qualitative and quantitative insights
Heather Haffner
November 13, 2019
Lactoferrin (LF) is a multifunctional protein that plays important physiological roles as one of the most concentrated proteins in many… Continue reading Modification of lactoferrin by peroxynitrite reduces its antibacterial activity and changes protein structure
Heather Haffner
November 13, 2019
Nanoparticles (NPs) consisting of biodegradable and biocompatible polymers may have the ability to deliver a cargo to specific tissue, cell… Continue reading Oligonucleotide loaded polypeptide‐peptide nanoparticles towards mitochondrial‐targeted delivery
Heather Haffner
November 13, 2019
Fibrillation of supramolecular building blocks represents an important model system for complex proteins and peptides, such as amyloidogenic proteins, displaying… Continue reading Secondary structure of end group functionalized oligomeric-L-lysines: investigations of solvent and structure dependent helicity
Heather Haffner
November 13, 2019
The HIV-1 accessory protein Vpu mediates the downregulation of several host cell proteins, an activity that is critical for viral… Continue reading Hydrophobic matching of HIV-1 Vpu transmembrane helix-helix interactions is optimized for subcellular location
Heather Haffner
November 13, 2019
The chemical investigation of the wheat plant pathogen Parastagonospora nodorum SN15 led to the purification of seven highly oxygenated acetylenic cyclohexanoids named… Continue reading Highly oxygenated isoprenylated cyclohexanoids from the fungus Parastagonospora nodorum SN15
Heather Haffner
November 13, 2019
Heather Haffner
November 13, 2019
Gamma secretase activating protein (GSAP) present in β-amyloid pathway orchestrates the formation of β-amyloid plaques by γ-secretase activation and is… Continue reading Tracing the GSAP–APP C-99 Interaction Site in the β-Amyloid Pathway Leading to Alzheimer’s Disease
Heather Haffner
November 13, 2019
Titanium and its alloys especially Ti6Al4V have long been used in biomedical implants. Although, Ti6Al4V is biocompatible, yet there has… Continue reading Silk fibroin coated TiO2 nanotubes for improved osteogenic property of Ti6Al4V bone implants
Heather Haffner
November 13, 2019
Heather Haffner
November 13, 2019
The origin of terrestrial bioorganic homochirality is one of the most important and unresolved problems in the study of chemical… Continue reading Origin of Terrestrial Bioorganic Homochirality and Symmetry Breaking in the Universe
Heather Haffner
November 13, 2019