2022 / Nature Communications
Chiral mesostructures exhibit distinctive twisting and helical hierarchical stacking ranging from atomic to micrometre scales with fascinating structural-chiral anisotropy properties.… Continue reading Synchronous quantitative analysis of chiral mesostructured inorganic crystals by 3D electron diffraction tomography
2022 / Nature Communications
The human insulin receptor signalling system plays a critical role in glucose homeostasis. Insulin binding brings about extensive conformational change… Continue reading Activation of the human insulin receptor by non-insulin-related peptides
2022 / Scientific Reports
Highest global cancer incidence of female breast cancer is a matter of great concern. HER2-positive breast cancers have high mortality… Continue reading Synthesis and comparative evaluation of 177Lu-labeled PEG and non-PEG variant peptides as HER2-targeting probes
2022 / Nature Communications
How soft corona, the protein corona’s outer layer, contributes to biological identity of nanomaterials is largely because capturing protein composition… Continue reading In situ analysis of nanoparticle soft corona and dynamic evolution
2022 / Scientific Reports
Antimicrobial peptides (AMPs) are being developed as potent alternative treatments to conventional antibiotics which are unlikely to induce bacterial resistance.… Continue reading Novel D-form of hybrid peptide (D-AP19) rapidly kills Acinetobacter baumannii while tolerating proteolytic enzymes
2022 / Scientific Reports
We evaluated the anti-leishmanial efficacy of different saturated medium-chain fatty acids (FAs, C8–C18) where FA containing C8 chain, caprylic acid… Continue reading Mechanistic insight into the role of mevalonate kinase by a natural fatty acid-mediated killing of Leishmania donovani
2022 / Communication Biology
SPACA6 is a sperm-expressed surface protein that is critical for gamete fusion during mammalian sexual reproduction. Despite this fundamental role,… Continue reading SPACA6 ectodomain structure reveals a conserved superfamily of gamete fusion-associated proteins
2014 / Food Bioprocess Technol (2014) 7:1344–1353
High pressure (HP, 200, 400, and 600 MPa)- and heat (60, 80, and 100 °C)-induced gelation, aggregation, and structural conformations… Continue reading Effects of High Pressure and Heat Treatments on Physicochemical and Gelation Properties of Rapeseed Protein Isolate
2020 / International Journal of Food Properties, 23:1, 955-970
Isoelectric precipitation was used to produce protein isolates (>90% protein contents) from three edible vegetable leaves. Amaranth (ALI), eggplant (ELI)… Continue reading Comparative study of the structural and functional properties of protein isolates prepared from edible vegetable leaves
2017 / International Journal of Food Science and Technology 2017
Bambara groundnut is a protein-rich traditional legume. In this study, storage proteins were isolated from three bambara landraces. Bambara protein… Continue reading Structure, composition and functional properties of storage proteins extracted from bambara groundnut (Vigna subterranea) landraces
2016 / Journal of Food Biochemistry Volume 41, Issue 2 e12321
African yam bean (Sphenostylis stenocarpa) seed flour was extracted with 0.5 M NaCl and the supernatant dialyzed against water to… Continue reading Modulation of the secondary and tertiary structures of African yam bean (Sphenostylis stenocarpa) seed globulins, albumins and protein concentrate by pH and NaCl
2022 / International Immunology, Volume 34, Issue 8, August 2022, Pages 421–434
Antigen-combining sites of the camelid heavy-chain antibody variable domain (VHH) are constructed by three complementarity-determining regions (CDR1, CDR2 and CDR3).… Continue reading An alpaca single-domain antibody (VHH) phage display library constructed by CDR shuffling provided high-affinity VHHs against desired protein antigens
2022 / Nature Communications
Medermycin, produced by Streptomyces species, represents a family of antibiotics with significant activity against Gram-positive pathogens. The biosynthesis of this… Continue reading Chimeric natural products derived from medermycin and the nature-inspired construction of their polycyclic skeletons
2022 / Nature Communications
Light harvesting is fundamental for production of ATP and reducing equivalents for CO2 fixation during photosynthesis. However, electronic energy transfer… Continue reading Allophycocyanin A is a carbon dioxide receptor in the cyanobacterial phycobilisome
2022 / Nature Communications
Aggregation of alpha-synuclein (α-Syn) drives Parkinson’s disease (PD), although the initial stages of self-assembly and structural conversion have not been… Continue reading Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity
2022 / Cell Discovery
The ongoing COVID-19 pandemic has continued to affect millions of lives worldwide, leading to the urgent need for novel therapeutic… Continue reading RNA G-quadruplex formed in SARS-CoV-2 used for COVID-19 treatment in animal models
2022 / Communication Biology
The prevalence of multidrug-resistant (MDR) pathogens raises public fears of untreatable infections and represents a huge health risk. There is… Continue reading The antimicrobial peptide LI14 combats multidrug-resistant bacterial infections
2022 / Nature Communications
Meiosis protein TEX12 is an essential component of the synaptonemal complex (SC), which mediates homologous chromosome synapsis. It is also… Continue reading Coiled-coil structure of meiosis protein TEX12 and conformational regulation by its C-terminal tip
2022 / ADVANCED MATERIALS
A combination of mechanochemistry and aqueous self-assembly is employed to prepare protein nanofibrils (PNFs) functionalized with perylene diimide (PDI) dyes.… Continue reading Water Processable Bioplastic Films from Functionalized Protein Fibrils
2022 / Nature Communications
Amyloid self-assembly is linked to numerous devastating cell-degenerative diseases. However, designing inhibitors of this pathogenic process remains a major challenge.… Continue reading Designed peptides as nanomolar cross-amyloid inhibitors acting via supramolecular nanofiber co-assembly
