2019 / The Protein Journal
The purification of phosphorylated proteins in a folded state and in large enough quantity for biochemical or biophysical analysis remains… Continue reading Scalable, Non-denaturing Purification of Phosphoproteins Using Ga3+-IMAC: N2A and M1M2 Titin Components as Study case
2019 / ACS Omega
We report an extensive study on the coordination behavior of chiral ditopic bridging ligands, which lead to metallosupramolecular polymers in… Continue reading Chiral Self-Sorting Process with Ditopic Ligands: Alternate or Block Metallopolymer Assembly as a Function of the Metal Ion
2019 / Scientific Reports
Foldamers, which are folded oligomers with well-defined conformations, have been recently reported to have a good cell-penetrating ability. α,α-Disubstituted α-amino… Continue reading Secondary structures and cell-penetrating abilities of arginine-rich peptide foldamers
2019 / JACS
Metal–organic polyhedra (MOP) are ultrasmall (typically 1–4 nm) porous coordination cages made from the self-assembly of metal ions and organic… Continue reading Postsynthetic Covalent and Coordination Functionalization of Rhodium(II)-Based Metal–Organic Polyhedra
2019 / Journal of Natural Products
Three new compounds, namely, 4-(4′-hydroxy-3′-methoxyphenyl)-3,5,7-trihydroxycoumarin (1) and sulawesins A (2) and B (3), were isolated from the propolis of stingless… Continue reading Propolis Components from Stingless Bees Collected on South Sulawesi, Indonesia, and Their Xanthine Oxidase Inhibitory Activity
2019 / Biochemistry
Amyloids are polypeptide supramolecular assemblies that have been historically associated with numerous pathologies. Nonetheless, recent studies have identified many amyloid… Continue reading Glycosaminoglycans Induce Amyloid Self-Assembly of a Peptide Hormone by Concerted Secondary and Quaternary Conformational Transitions
2019 / RSC Advances
Human neuroglobin (Ngb) forms an intramolecular disulfide bond between Cys46 and Cys55, with a third Cys120 near the protein surface,… Continue reading Enhancement of protein stability by an additional disulfide bond designed in human neuroglobin
2019 / International Journal of Peptide Research and Therapeutics
Human truncated parathyroid hormone [hPTH (1–34)], a peptide hormone which accelerated the research interest towards the theraputical applications. This study… Continue reading Characterization and Expression Profiling of Recombinant Parathyroid Hormone (rhPTH) Analog 1–34 in Escherichia coli, Precise with Enhanced Biological Activity
2019 / Redox Biology
The aggregation of α-synuclein (α-syn) into amyloid fibrils is a major pathological hallmark of Parkinson’s disease (PD) and other synucleinopathies. The mechanisms underlying the… Continue reading Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity
2019 / Amino Acids
Knowing the key features of the structure and the biochemistry of proteins is crucial to improving enzymes of industrial interest… Continue reading Low-resolution structure, oligomerization and its role on the enzymatic activity of a sucrose-6-phosphate hydrolase from Bacillus licheniformis
2019 / Advanced Functional Materials
Surface nanotopograpy has been recognized as an important regulator of cellular responses including those of immune cells, the latter being… Continue reading Nanotopography‐Induced Unfolding of Fibrinogen Modulates Leukocyte Binding and Activation
2019 / Biomolecules
The interaction of neuropeptides, vasoactive intestinal peptide (VIP), or growth hormone-releasing hormone (GHRH), with a cationic carbosilane dendrimer forms dendriplexes… Continue reading Anticancer Activity of Dendriplexes against Advanced Prostate Cancer from Protumoral Peptides and Cationic Carbosilane Dendrimers
2019 / Langmuir
Two enantiomeric gelator molecules containing anthracene moiety were assembled at the air/water interface and several new insights into the films… Continue reading Spreading Films of Anthracene-Containing Gelator Molecules at the Air/Water Interface: Nanorod and Circularly Polarized Luminescence
2019 / Crystal Growth & Design
Magnetite nanoparticles in the magnetosomes formed by magnetotactic bacteria present unique magnetic properties that make them the ideal nanoparticle with… Continue reading Protein Conservation Method Affects MamC-Mediated Biomineralization of Magnetic Nanoparticles
2019 / Scientific Reports
This paper focuses on the nucleoprotein (NP) of the newly identified member of the Orthomyxoviridae family, Influenza D virus. To date several… Continue reading The structure of the nucleoprotein of Influenza D shows that all Orthomyxoviridae nucleoproteins have a similar NPCORE, with or without a NPTAILfor nuclear transport
2019 / Journal of Peptide Science
The study of the process of HIV entry into the host cell and the creation of biomimetic nanosystems that are… Continue reading Modeling interaction between gp120 HIV protein and CCR5 receptor
2019 / Scientific Reports
p53 is frequently mutated in human cancers. Its levels are tightly regulated by the E3 ubiquitin ligase MDM2. The complex between… Continue reading Kinetic and thermodynamic effects of phosphorylation on p53 binding to MDM2
2019 / Extremophiles
The stability of dimeric cytochrome c′ from a thermophile, as compared with that of a homologous mesophilic counterpart, is attributed to… Continue reading Stability of cytochromes c′ from psychrophilic and piezophilic Shewanella species: implications for complex multiple adaptation to low temperature and high hydrostatic pressure
2019 / Advanced Functional Materials
Herein, a simple and facile strategy is described to obtain chiroptically active semiconductor thin films by blending of poly(3‐alkylthiophene)s, which… Continue reading Chiroptical‐Conjugated Polymer/Chiral Small Molecule Hybrid Thin Films for Circularly Polarized Light‐Detecting Heterojunction Devices
2019 / bioRxiv
The biogenesis of the photosynthetic apparatus in developing chloroplasts requires the assembly of proteins encoded on both nuclear and chloroplast… Continue reading GUN1 regulates tetrapyrrole biosynthesis
