This paper reports the synthesis of a planar-chiral monohydroxy-functionalized pillar[5]arene amenable to a wide variety of chemical modifications. Chiral resolution… Continue reading Chiral discrimination of 2-heptlyaminium salt by planar-chiral monohydroxy-functionalized pillar[5]arenes
Heather Haffner
April 9, 2019
A metabolic conversion study on microbes is known as one of the most useful tools to predict the xenobiotic metabolism… Continue reading Biotransformed Metabolites of the Hop Prenylflavanone Isoxanthohumol
Heather Haffner
April 9, 2019
Heather Haffner
April 9, 2019
In this work, we have studied the effect of Crotalus basiliscus snake venom on the redox reaction of myoglobin (Mb), and by… Continue reading Effect of Crotalus basiliscus snake venom on the redox reaction of myoglobin
Heather Haffner
April 9, 2019
Amyloid aggregation has been associated with numerous human pathological diseases. A recent study has demonstrated that silk fibroin intermittently endorses amyloidogenesis in vivo. In… Continue reading Modulation of aggregation of silk fibroin by synergistic effect of the complex of curcumin and β-cyclodextrin
Heather Haffner
April 9, 2019
Lyotropic bicontinuous cubic (QII) phases have attracted increasing attention as nanostructured fluidic matrices for some bio-polymers including enzymes and DNA.… Continue reading Improvement of lipidic bicontinuous cubic phases by the addition of a zwitterion with strong hydration ability and kosmotropicity
Heather Haffner
April 9, 2019
Protein misfolding plays a critical role in the manifestation of amyloidosis type diseases. Therefore, understanding protein unfolding and the ability… Continue reading Detecting lysozyme unfolding via the fluorescence of lysozyme encapsulated gold nanoclusters
Heather Haffner
April 9, 2019
The mouse Major Urinary Proteins (MUPs) contain a conserved β-barrel structure with a characteristic central hydrophobic pocket that binds a… Continue reading Effects of point mutations in the binding pocket of the mouse major urinary protein MUP20 on ligand affinity and specificity
Heather Haffner
April 9, 2019
Heather Haffner
April 9, 2019
A wide range of bacterial pathogens have been shown to form biofilms, which significantly increase their resistance to environmental stresses,… Continue reading Physical Determinants of Amyloid Assembly in Biofilm Formation
Heather Haffner
April 9, 2019
The G-quadruplex-forming telomeric sequence (TTAGGG)4TT was investigated by polarized Ultraviolet Resonance Raman Scattering (UVRR) at 266 nm. The presence of… Continue reading Crowding and conformation interplay on human DNA G-quadruplex by ultraviolet resonant Raman scattering
Heather Haffner
April 9, 2019
The aggregation of α-synuclein (α-Syn) has been implicated strongly in Parkinson’s disease (PD). The intrinsically disordered nature of α-Syn makes… Continue reading Modulation of α-Synuclein Aggregation by Cytochrome c Binding and Hetero-dityrosine Adduct Formation
Heather Haffner
April 9, 2019
The molecular interactions between two single-chain lysosomotropic surfactants DMM-11 (2-Dodecanoyloxyethyl)trimethylammonium bromide) and DMPM-11 (2-Dodecanoyloxypropyl)trimethylammonium bromide) with a small heme-protein(cytochrome c (cyt-c)) in Hepes buffer (pH = 7.4)… Continue reading Biomolecular interactions of lysosomotropic surfactants with cytochrome c and its effect on the protein conformation: A biophysical approach
Heather Haffner
April 9, 2019
Heather Haffner
April 9, 2019
Even though the bis‐lactam peptide stapling with the [i, i + 7] and the [i, i + 11] systems has been known to be… Continue reading Bis‐Lactam Peptide [i, i + 4]‐Stapling
Heather Haffner
April 9, 2019
Heather Haffner
April 9, 2019
Characterization of small oligomers formed at an early stage of amyloid formation is critical to understanding molecular mechanism of pathogenic… Continue reading Transthyretin Aggregation Pathway toward the Formation of Distinct Cytotoxic Oligomers
Heather Haffner
April 9, 2019
Heather Haffner
April 9, 2019
Many organisms possess the ability to produce metal-binding proteins to absorb cadmium. Metallothioneins, an important family of cysteine-rich metal-binding proteins,… Continue reading Purification and Characterization of a Cadmium-Binding Protein from Lentinula edodes
Heather Haffner
April 9, 2019
Peptide-mediated routes to the synthesis of plasmonic nanoparticles have been drawing increasing attention for the development of chiroptically active nanoscale… Continue reading In Situ Generation of Chiroptically-Active Gold-Peptide Superstructures Promoted by Iodination
Heather Haffner
April 9, 2019