2018 / Chemistry of Materials
Templating methods, combined with colloidal chemistry synthesis, provide a strategy to fabricate inorganic nanomaterials with controllable architectures. Computationally designed peptide… Continue reading Fabrication of One- and Two-Dimensional Gold Nanoparticle Arrays on Computationally Designed Self-Assembled Peptide Templates
2018 / ACS Omega
Investigation into the interactions between biomolecules DNA/RNA and carbon nanomaterials is very important for applications in bioassays and bioanalysis. Graphene… Continue reading Reduced Graphene Oxide-Oligonucleotide Interfaces: Understanding Based on Electrochemical Oxidation of Guanines
2018 / ChemBioChem
R‐ω‐Transaminases (RTAs) catalyse the conversion of R‐configured amines [e.g., (R)‐1‐phenylethylamine] into the corresponding ketones (e.g., acetophenone), by transferring an amino group… Continue reading Covalent Linkage of an R‐ω‐Transaminase to a d‐Amino Acid Oxidase through Protein Splicing to Enhance Enzymatic Catalysis of Transamination
2019 / Luminescence
This paper discusses multi‐spectroscopic and molecular docking analysis of the interaction between atenolol (ATN) and deoxyribose nucleic acid (DNA) using… Continue reading Comprehensive analysis of the atenolol – DNA complex by viscometric, molecular docking and spectroscopic techniques
2019 / Journal of Molecular Structure
We have reported the eco-friendly gold nanoparticles (AuNPs) from 15% aqueous leaf extract of therapeutic plant Nymphaea nouchali where leaf extract acts as both… Continue reading Spectroscopic study on interaction of Nymphaea nouchali leaf extract mediated bactericidal gold nanoparticles with human serum albumin
2019 / Applied Microbiology and Biotechnology
Increasing drug resistance in pathogens including Mycobacterium tuberculosis (MTB) has been ascribed to mutations in the known target genes. However, many of… Continue reading Ethambutol targets the glutamate racemase of Mycobacterium tuberculosis—an enzyme involved in peptidoglycan biosynthesis
2019 / ACS Nano
Self-assembly of peptides and amyloid fibrils offers an appealing approach for creating chiral nanostructures, which has promising applications in the… Continue reading Aromatic Motifs Dictate Nanohelix Handedness of Tripeptides
2019 / Journal of Biological Chemistry
In nontypeable Haemophilus influenzae (NTHi), the oligopeptide-binding protein (OppA) serves as the substrate-binding protein (SBP) of the oligopeptide transport system responsible for… Continue reading Oligopeptide-binding protein from nontypeable Haemophilus influenzae has ligand-specific sites to accommodate peptides and heme in the binding pocket
2018 / Scientific Reports
Single molecular changes on a tripeptide can have dramatic effects on their self-assembly and hydrogelation. Herein, we explore C-terminal residue variation… Continue reading C-Terminal Residue of Ultrashort Peptides Impacts on Molecular Self-Assembly, Hydrogelation, and Interaction with Small-Molecule Drugs
2019 / Analytical and Bioanalytical Chemistry
Two fluorescent aptasensor methods were developed for the detection of ATP in biochemical systems. The first method consisted of a… Continue reading Comparison of turn-on and ratiometric fluorescent G-quadruplex aptasensor approaches for the detection of ATP
2019 / European Journal of Inorganic Chemistry
New luminescent Pt(II) complexes with the chiral counter anions [PtCl(tpy)](L‐Hta) (1‐L) and [PtCl(tpy)](DL‐Hta) (1‐DL; tpy = 2,2’:6’,2’’‐terpyridine; L‐H2ta = L‐tartaric… Continue reading Effect of the Chirality of Counter Anions on the Vapochromic Behavior of Luminescent Pt(II) Complexes
2019 / The FASEB Journal
The amyloid precursor–like protein 2 (APLP2) molecule is a type I transmembrane protein that is crucial for survival, cell-cell adhesion,… Continue reading The crystal structure of amyloid precursor–like protein 2 E2 domain completes the amyloid precursor protein family
2019 / The Journal of Physical Chemistry C
Two diketopyrrolopyrroles (DPP) and three rylenes (NDI, dPyr PDI, and dEO PDI) were combined to form six hierarchical superstructures that… Continue reading Singlet Fission in Combinatorial Diketopyrrolopyrrole—Rylene Supramolecular Films
2019 / Organic & Biomolecular Chemistry
To systematically determine the effect of N2-heteroaryl modification on the stability of G-quadruplex structures, six types of N2-heteroarylated deoxyguanosines were… Continue reading Tolerance of N2-heteroaryl modifications on guanine bases in a DNA G-quadruplex
2019 / Journal of Agricultural and Food Chemistry
Novel Gemini dodecyl O-glucoside-based primary, secondary, and tertiary vesicles were developed in this work utilizing layer-by-layer deposition of polysaccharides (e.g., sodium… Continue reading Interaction between Gemini Dodecyl O-Glucosides-Based Multilayer Vesicles and β-Lactoglobulin: The Dominant Role of Surface Charge
2019 / ACS Chemical Neuroscience
Six alpha-Synuclein point mutations are currently known to be associated with familial par-kinsonism: A30P, E46K, H50Q, G51D, A53E and A53T.… Continue reading Different effects of alpha-Synuclein mutants on lipid binding and aggregation detected by single molecule fluorescence spectroscopy and ThT fluorescence-based measurements
2019 / bioRxiv
Cell division by meiosis involves an extraordinary chromosome choreography including pairing, synapsis and crossing over between homologous chromosomes. The many… Continue reading A pseudo-meiotic centrosomal function of TEX12 in cancer
2019 / Chromosoma
The reduction in chromosome number during meiosis is essential for the production of haploid germ cells and thereby fertility. To… Continue reading Molecular structure of human synaptonemal complex protein SYCE1
2018 / Science Advances
Stereochemistry is vital for pharmaceutical development and can determine drug efficacy. Herein, 10 pairs of asymmetric triplex metallohelix enantiomers as… Continue reading Stereochemistry and amyloid inhibition: Asymmetric triplex metallohelices enantioselectively bind to Aβ peptide
2018 / Science Advances
In every established species, protein-protein interactions have evolved such that they are fit for purpose. However, the molecular details of… Continue reading Structure and dynamics conspire in the evolution of affinity between intrinsically disordered proteins
