Tuning of Optical Properties and Thermal Cycloreversion Reactivity of Photochromic Diarylbenzene by Introducing Electron-Donating Substituents

2019 / Journal of Physical Chemistry C

Thermally reversible photochromic compounds having excellent physicochemical properties can be exploited for many practical applications, such as ophthalmic lenses, real-time… Continue reading Tuning of Optical Properties and Thermal Cycloreversion Reactivity of Photochromic Diarylbenzene by Introducing Electron-Donating Substituents

Leah Pandiscia, PhD

The intrinsically disordered carboxy-terminus of troponin-T binds to troponin-C to modulate myocardial force generation

2019 / Journal of Biological Chemistry

Aberrant regulation of myocardial force production represents an early biomechanical defect associated with sarcomeric cardiomyopathies, but the molecular mechanisms remain… Continue reading The intrinsically disordered carboxy-terminus of troponin-T binds to troponin-C to modulate myocardial force generation

Leah Pandiscia, PhD

Molecular and macromolecular crowding-induced stabilization of proteins: Effect of dextran and its building block alone and their mixtures on stability and structure of lysozyme

2019 / International Journal of Biological Macromolecules

Dextran 70 and its building block (glucose) has been used as macromolecular crowder and osmolyte, respectively. The difference in size… Continue reading Molecular and macromolecular crowding-induced stabilization of proteins: Effect of dextran and its building block alone and their mixtures on stability and structure of lysozyme

Leah Pandiscia, PhD

Physico-chemical characterization and computational studies of a new organic adduct 3-amino-2-chloropyridine: Benzilic acid, crystal for third order harmonic generation

2020 / Journal of Molecular Structure

Single crystals of 3-amino-2-chloropyridine:benzilic acid, an organic adduct have been grown by slow evaporation technique successfully. The structure of the… Continue reading Physico-chemical characterization and computational studies of a new organic adduct 3-amino-2-chloropyridine: Benzilic acid, crystal for third order harmonic generation

Leah Pandiscia, PhD

Insight into the binding and conformational changes of hemoglobin/lysozyme with bimetallic alloy nanoparticles using various spectroscopic approaches

2020 / Journal of Molecular Liquids

This study explores the adsorption and binding interaction of bovine hemoglobin (BHb) and lysozyme (Lys) with gold/silver alloy nanoparticles (Au/Ag… Continue reading Insight into the binding and conformational changes of hemoglobin/lysozyme with bimetallic alloy nanoparticles using various spectroscopic approaches

Leah Pandiscia, PhD

Bioimaging Applications of Carbon dots (C. dots) and its Cystamine Functionalization for the Sensitive Detection of Cr(VI) in Aqueous Samples

2020 / Journal of Fluorescence

In this study, one step hydrothermal synthetic strategy was adopted for preparing carbon dots (C. dots) from jeera (Cumin: Cuminum cyminum),… Continue reading Bioimaging Applications of Carbon dots (C. dots) and its Cystamine Functionalization for the Sensitive Detection of Cr(VI) in Aqueous Samples

Leah Pandiscia, PhD

Structural Diversity Ranging from Oligonuclear Complexes to 1‐D and 2‐D Coordination Polymers Generated by Tetrasubstituted Adamantane and Spirobifluorene Derivatives

2019 / European Journal of Inorganic Chemistry

Using tetrahedral and tetragonal spacers, seven new complexes have been obtained: [Co(hfac)2(L1)0.5] 1, [Cu2(hfac)4L2] 2, [Co(hfac)2L2] 3, [Co(hfac)2(L2)0.5]·8H2O 4, [AgL2](SbF6)·CH3COOC2H5 5, [Mn(hfac)2(L3)0.5] 6, [Zn(OAc)2(L3)0.5] 7, {L1 = 1,3,5,7‐tetrakis(4‐cyanophenyl)adamantane,… Continue reading Structural Diversity Ranging from Oligonuclear Complexes to 1‐D and 2‐D Coordination Polymers Generated by Tetrasubstituted Adamantane and Spirobifluorene Derivatives

Leah Pandiscia, PhD

Structures of 1:1 and 2:1 complexes of BMVC and MYC promoter G-quadruplex reveal a mechanism of ligand conformation adjustment for G4-recognition 

2019 / Nucleic Acids Research

BMVC is the first fluorescent probe designed to detect G-quadruplexes (G4s) in vivo. The MYC oncogene promoter forms a G4 (MycG4)… Continue reading Structures of 1:1 and 2:1 complexes of BMVC and MYC promoter G-quadruplex reveal a mechanism of ligand conformation adjustment for G4-recognition 

Leah Pandiscia, PhD

Biophysical and computational approaches to unravel the molecular interaction mechanism of bromodeoxyuridine, a proliferative marker with human serum albumin

2019 / Monatshefte für Chemie - Chemical Monthly

The interaction of a nucleoside analogue bromodeoxyuridine (BrdU) with human serum albumin (HSA) was studied to investigate the binding phenomenon… Continue reading Biophysical and computational approaches to unravel the molecular interaction mechanism of bromodeoxyuridine, a proliferative marker with human serum albumin

Leah Pandiscia, PhD

Facile sonochemical synthesis of Ag2O-guar gum nanocomposite as a visible light photocatalyst for the organic transformation reactions

2020 / Journal of Hazardous Materials

Silver Oxide (Ag2O)-Guar gum nanocomposite was fabricated via a simple sonochemical co-precipitation method. The obtained photocatalyst was characterized with various… Continue reading Facile sonochemical synthesis of Ag2O-guar gum nanocomposite as a visible light photocatalyst for the organic transformation reactions

Leah Pandiscia, PhD