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Green synthesized carbon dots embedded in silica molecularly imprinted polymers, characterization and application as a rapid and selective fluorimetric sensor for determination of thiabendazole in juices

2020 / Food Chemistry

An eco-friendly method was used to synthesize carbon dots (CDs) from Rosemary leaves, as a carbon source. The as-synthesized CDs… Continue reading Green synthesized carbon dots embedded in silica molecularly imprinted polymers, characterization and application as a rapid and selective fluorimetric sensor for determination of thiabendazole in juices

Leah Pandiscia, PhD March 24, 2020

Synthesis and characterization of quinoline-carbaldehyde derivatives as novel inhibitors for leishmanial methionine aminopeptidase 1

2020 / European Journal of Medicinal Chemistry

Methionine aminopeptidase 1 of Leishmania donovani (LdMetAP1) is a novel antileishmanial target for its role in vital N-terminal methionine processing. After LdMetAP1 expression… Continue reading Synthesis and characterization of quinoline-carbaldehyde derivatives as novel inhibitors for leishmanial methionine aminopeptidase 1

Leah Pandiscia, PhD March 24, 2020

Sensitive spectrofluorimetric assay based on micelle enhanced protocol for the determination of hepatitis C antiviral agent (simeprevir): Application to dosage form and human plasma

2020 / Microchemical Journal

Simeprevir (SMV) is a newly introduced, powerful hepatitis C antiviral agent. We hereby introduce a validated rapid, sensitive and straight… Continue reading Sensitive spectrofluorimetric assay based on micelle enhanced protocol for the determination of hepatitis C antiviral agent (simeprevir): Application to dosage form and human plasma

Leah Pandiscia, PhD March 24, 2020

S-Nitrosothiols as potential therapeutics to induce a mobilizable vascular store of nitric oxide to counteract endothelial dysfunction

2019 / Biochemical Pharmacology

Endothelial dysfunction predisposing to cardiovascular diseases is defined as an imbalance in the production of vasodilating factors, such as nitric… Continue reading S-Nitrosothiols as potential therapeutics to induce a mobilizable vascular store of nitric oxide to counteract endothelial dysfunction

Leah Pandiscia, PhD March 24, 2020

Localized controlled release of bevacizumab and doxorubicin by thermo-sensitive hydrogel for normalization of tumor vasculature and to enhance the efficacy of chemotherapy

2019 / International Journal of Pharmaceutics

In a malignant tumor, overexpression of pro-angiogenic factors like vascular endothelial growth factor (VEGF) provokes the production of pathologic vascular… Continue reading Localized controlled release of bevacizumab and doxorubicin by thermo-sensitive hydrogel for normalization of tumor vasculature and to enhance the efficacy of chemotherapy

Leah Pandiscia, PhD March 24, 2020

Entrapment in micellar assemblies switches the excimer population of potential therapeutic luminophore azapodophyllotoxin

2019 / Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy

Azapodophyllotoxin is a new class of anti-tumor agent with brilliant therapeutic activity and understanding its physicochemical nature in bio-mimetic microenvironments… Continue reading Entrapment in micellar assemblies switches the excimer population of potential therapeutic luminophore azapodophyllotoxin

Leah Pandiscia, PhD March 24, 2020

Exploring the interactions of a Tb(III)–quercetin complex with serum albumins (HSA and BSA): spectroscopic and molecular docking studies

2019 / Luminescence

Serum albumins (human serum albumin (HSA) and bovine serum albumin (BSA), two main circulatory proteins), are globular and monomeric macromolecules… Continue reading Exploring the interactions of a Tb(III)–quercetin complex with serum albumins (HSA and BSA): spectroscopic and molecular docking studies

Leah Pandiscia, PhD March 24, 2020

In-situ synthesis of metal nanoparticles@metal−organic frameworks: Highly effective catalytic performance and synergistic antimicrobial activity

2019 / Journal of Hazardous Materials

M-NP@Zn-BIF (M-NP = Ag or Cu nanoparticle; Zn-BIF is a zinc-based boron imidazolate framework, Zn2(BH(2-mim)3)2(obb); 2-mim = 2-methylimidazole; obb = 4,4′-oxybis(benzoate)) composites were successfully in-situ synthesized by utilizing… Continue reading In-situ synthesis of metal nanoparticles@metal−organic frameworks: Highly effective catalytic performance and synergistic antimicrobial activity

Leah Pandiscia, PhD March 24, 2020

Hydrogen bond analysis of a third order nonlinear optical crystal, 2-amino-5-bromopyridinium benzilate, using structural and computational characterizations

2020 / Journal of Molecular Structure

The molecular structure of a proton transfer organic material, 2-amino-5-bromopyridinium benzilate crystal, grown by slow-evaporation solution growth technique has been… Continue reading Hydrogen bond analysis of a third order nonlinear optical crystal, 2-amino-5-bromopyridinium benzilate, using structural and computational characterizations

Leah Pandiscia, PhD March 24, 2020

Blue-emitting dendritic molecule with dual functionality as host and dopant for solution-processed white OLEDs with red-emitting material

2019 / Synthetic Metals

In this study, a three-armed dendritic molecule, 1,3,5-tris(10-(4-(2,6-diphenylpyrimidin-4-yl)phenyl)-9,9-diphenyl-9,10-dihydroacridin-2-yl)benzene (3PDPAc), was successfully synthesized and utilized as a blue dopant and its… Continue reading Blue-emitting dendritic molecule with dual functionality as host and dopant for solution-processed white OLEDs with red-emitting material

Leah Pandiscia, PhD March 24, 2020