Potential complementation effects of two disease-associated mutations in tetrameric glutaryl-CoA dehydrogenase is due to inter subunit stability-activity counterbalance

2019 / Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Glutaric Aciduria Type I (GA-I), is an autosomal recessive neurometabolic disease caused by mutations in the GCDH gene that encodes for glutaryl-CoA… Continue reading Potential complementation effects of two disease-associated mutations in tetrameric glutaryl-CoA dehydrogenase is due to inter subunit stability-activity counterbalance

Leah Pandiscia, PhD

A simple Schiff base platform: sensing of Al3+ ions in an aqueous medium

2019 / Journal of Chemical Sciences

A simple Schiff base probe PADP ((1,2-phenylenebis(azanylylidene)) bis(methanylylidene))bis(3-(diethylamino)phenol) was synthesized from 4-(diethylamino)salicylaldehyde and o-phenylenediamine and has been characterized using analytical and spectral methods.… Continue reading A simple Schiff base platform: sensing of Al3+ ions in an aqueous medium

Leah Pandiscia, PhD

Sequential halochromic/mechanochromic luminescence of pyridyl-substituted solid-state emissive dyes: thermally controlled stepwise recovery of the original emission color

2020 / CrystEngComm

Stimuli-responsive organic dyes that switch the color of their solid-state emission upon exposure to external stimuli represent an important class… Continue reading Sequential halochromic/mechanochromic luminescence of pyridyl-substituted solid-state emissive dyes: thermally controlled stepwise recovery of the original emission color

Leah Pandiscia, PhD

Serendipitous Assembly of Mixed Phase BiVO4 on B-Doped g-C3N4: An Appropriate p–n Heterojunction for Photocatalytic O2 evolution and Cr(VI) reduction

2019 / Inorganic Chemistry

Type II p–n heterojunction B-doped g-C3N4/BiVO4 moieties have been fabricated by depositing n-type BiVO4 on the surface of p-type 1 wt %… Continue reading Serendipitous Assembly of Mixed Phase BiVO4 on B-Doped g-C3N4: An Appropriate p–n Heterojunction for Photocatalytic O2 evolution and Cr(VI) reduction

Leah Pandiscia, PhD

Novel 4-quinoline-thiosemicarbazone derivatives: Synthesis, antiproliferative activity, in vitro and in silico biomacromolecule interaction studies and topoisomerase inhibition

2019 / European Journal of Medicinal Chemistry

Twelve 2-(quinolin-4-ylmethylene) hydrazinecarbothioamide derivatives were synthetized and their biological properties were investigated, among which, the ability to interact with DNA… Continue reading Novel 4-quinoline-thiosemicarbazone derivatives: Synthesis, antiproliferative activity, in vitro and in silico biomacromolecule interaction studies and topoisomerase inhibition

Leah Pandiscia, PhD

Effect of the Position of the Cyano Group on Molecular Recognition, Supramolecular Superhelix Architecture, and Spontaneous Resolution of Aza[7]helicenes

2019 / Crystal Growth & Design

Five derivatives of cyano-containing 9-alkyl-9H-aza[7]helicene were synthesized and their behavior in the crystallization was investigated. Only one of the derivatives,… Continue reading Effect of the Position of the Cyano Group on Molecular Recognition, Supramolecular Superhelix Architecture, and Spontaneous Resolution of Aza[7]helicenes

Leah Pandiscia, PhD