Molecular design of highly effective thermally activated delayed fluorescence emitters based on ortho-substituted donor-acceptor-donor pyridinecarbonitrile derivatives and their application for high-performance OLEDs

2019 / Dyes and Pigments

In this work, we designed and investigated two TADF molecules, AcCN and PxCN, introducing donor moieties into the 3,5-position of 4-pyridinecarbonitrile acceptor core.… Continue reading Molecular design of highly effective thermally activated delayed fluorescence emitters based on ortho-substituted donor-acceptor-donor pyridinecarbonitrile derivatives and their application for high-performance OLEDs

Leah Pandiscia, PhD

Interaction of a sphingolipid with human serum albumin in the native, thermally denatured and chemically denatured states: Emission wavelength-dependent photophysical revelation

2019 / Journal of Molecular Liquids

The present study exhibits a spectroscopic deciphering of the effect of a phosphosphingolipid, sphingomyelin (SM), on native as well as… Continue reading Interaction of a sphingolipid with human serum albumin in the native, thermally denatured and chemically denatured states: Emission wavelength-dependent photophysical revelation

Leah Pandiscia, PhD

Enhancement of the Photofunction of Phosphorescent Pt(II) Cyclometalated Complexes Driven by Substituents: Solid-State Luminescence and Circularly Polarized Luminescence

2019 / Journal of Organic Chemistry

Ligand functionalization is an attractive strategy for enhancing the performance of metal-based phosphorescent emitters. Here, we report the synthesis and… Continue reading Enhancement of the Photofunction of Phosphorescent Pt(II) Cyclometalated Complexes Driven by Substituents: Solid-State Luminescence and Circularly Polarized Luminescence

Leah Pandiscia, PhD

Insights into formation of anatase TiO2 nanoparticles from peroxo titanium complex degradation under microwave-assisted hydrothermal treatment

2019 / Ceramics International

Several methods for the synthesis of anatase TiO2 have been reported in the literature. In particular, the microwave-assisted hydrothermal crystallization of… Continue reading Insights into formation of anatase TiO2 nanoparticles from peroxo titanium complex degradation under microwave-assisted hydrothermal treatment

Leah Pandiscia, PhD

Adsorption behaviors of Cu2+, Zn2+ and Cd2+ onto proteins, humic acid, and polysaccharides extracted from sludge EPS: Sorption properties and mechanisms

2019 / Bioresource Technology

To clarify the adsorption behaviors of typical heavy metals onto sludge extracellular polymeric substances (EPS), the adsorption capacities and mechanisms,… Continue reading Adsorption behaviors of Cu2+, Zn2+ and Cd2+ onto proteins, humic acid, and polysaccharides extracted from sludge EPS: Sorption properties and mechanisms

Leah Pandiscia, PhD

Structural studies on the individual domains of human γS-crystallin and its G57W mutant unfolds mechanistic insights into childhood cataracts

2019 / Biochemical and Biophysical Research Communications

Inter-domain interactions tune the exceptional stability of human γS-crystallin (γS-WT) in the eye lens, which lasts a lifetime with no… Continue reading Structural studies on the individual domains of human γS-crystallin and its G57W mutant unfolds mechanistic insights into childhood cataracts

Leah Pandiscia, PhD

A novel enantioselective SGNH family esterase (NmSGNH1) from Neisseria meningitides: Characterization, mutational analysis, and ester synthesis

2019 / Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

In Neisseria sp., SGNH family esterases are involved in bacterial pathogenesis as well as cell wall peptidoglycan maturation. Here, a novel enantioselective… Continue reading A novel enantioselective SGNH family esterase (NmSGNH1) from Neisseria meningitides: Characterization, mutational analysis, and ester synthesis

Leah Pandiscia, PhD

Nonnucleoside Reverse Transcriptase Inhibitor Hypersusceptibility and Resistance by Mutation of Residue 181 in HIV-1 Reverse Transcriptase

2019 / Antimicrobial Agents and Chemotherapy

Substitutions at residue Y181 in HIV-1 reverse transcriptase (RT), in particular, Y181C, Y181I, and Y181V, are associated with nonnucleoside RT… Continue reading Nonnucleoside Reverse Transcriptase Inhibitor Hypersusceptibility and Resistance by Mutation of Residue 181 in HIV-1 Reverse Transcriptase

Leah Pandiscia, PhD

Light-sensitive dextran-covered PNBA nanoparticles to continuously or discontinuously improve the drug release

2019 / Colloids and Surfaces B: Biointerfaces

In this work, photo-sensitive core/shell nanoparticles (NPs) based on biocompatible dextran-g-poly(o-nitrobenzyl acrylate) copolymers (Dex-g-PNBA), containing dextran as hydrophilic backbone and… Continue reading Light-sensitive dextran-covered PNBA nanoparticles to continuously or discontinuously improve the drug release

Leah Pandiscia, PhD

An investigation on host-guest complexation of Metformin hydrochloride with hydroxypropyl-α-cyclodextrin for enhanced oral bioavailability

2019 / Materials Proceedings: Today

Metformin hydrochloride is an orally administered biguanide which is an oral anti-hyperglycemic agent. It shows incomplete absorption from the gastrointestinal… Continue reading An investigation on host-guest complexation of Metformin hydrochloride with hydroxypropyl-α-cyclodextrin for enhanced oral bioavailability

Leah Pandiscia, PhD

Concept of Stagnant Capillarity Water in the Nanoporous SiO2@(Zn,Ni)(O,S) Nanocomposite Photocatalyst as a Strategy to Improve Hydrogen Evolution

2019 / ACS Applied Materials & Interfaces

(Zn,Ni)(O,S) nanoparticles were uniformly deposited on nanoporous SiO2spheres to form SiO2@(Zn,Ni)(O,S) nanocomposites (NCs). To obtain optimum deposition of (Zn,Ni)(O,S) on… Continue reading Concept of Stagnant Capillarity Water in the Nanoporous SiO2@(Zn,Ni)(O,S) Nanocomposite Photocatalyst as a Strategy to Improve Hydrogen Evolution

Leah Pandiscia, PhD

Inhibition of Aβ1–42 Fibrillation by Chaperonins: Human Hsp60 Is a Stronger Inhibitor than Its Bacterial Homologue GroEL

2019 / ACS Chemical Neuroscience

Alzheimer’s disease is a chronic neurodegenerative disease characterized by the accumulation of pathological aggregates of amyloid beta peptide. Many efforts… Continue reading Inhibition of Aβ1–42 Fibrillation by Chaperonins: Human Hsp60 Is a Stronger Inhibitor than Its Bacterial Homologue GroEL

Leah Pandiscia, PhD