Therapeutic biologics (i.e., proteins) have been widely recognized for the treatment, prevention, and cure of a variety of human diseases… Continue reading Recombinant Spider Silk Hydrogels for Sustained Release of Biologicals
Leah Pandiscia, PhD
August 13, 2018
Silica-gelatin hybrid aerogels, introduced recently as drug delivery devices, were investigated for biocompatibility with SCC tumor cells by a time-lapse video-microscopy technique. The… Continue reading Biocompatible silica-gelatin hybrid aerogels covalently labeled with fluorescein
Leah Pandiscia, PhD
August 13, 2018
The solvatochromic fluorescence behavior of cinnamoyl pyrone derivatives has been studied in several polar and non-polar solvents. The fluorescence spectra of these compounds exhibit red… Continue reading Solvatochromic fluorescence characteristics of cinnamoyl pyrone derivatives
Leah Pandiscia, PhD
August 13, 2018
α-synuclein plays a key role in the pathogenesis of Parkinson’s disease (PD); its deposits are found as amyloid fibrils in… Continue reading Oleuropein aglycone stabilizes the monomeric α-synuclein and favours the growth of non-toxic aggregates
Leah Pandiscia, PhD
August 13, 2018
The alkyne arms containing zinc(II) N2O2 ligation complexes (1) and (2) were prepared from 2,2′‐{cyclohexane‐1,2‐diylbis[nitrilo(E)methylylidene]}bis[5‐(prop‐2‐yn‐1‐yloxy)phenol] (L1) and 2,2′‐{1,2‐phenylenebis[nitrilo(E)methylylidene]}bis[5‐(prop‐2‐yn‐1‐yloxy)phenol] (L2) and characterized… Continue reading Zinc(II)‐N2O2 ligation complex‐based DNA/protein binder and cleaver having enhanced cytotoxic and phosphatase activity
Leah Pandiscia, PhD
August 13, 2018
4-Bromo substituted [2.2]paracyclophane-1,9-diene was synthesized from the corresponding dithia[3.3]paracyclophane in three steps through benzyne Steven rearrangement, oxidation, and a thermal… Continue reading Synthesis, aggregation induced emission and through space conjugation of triphenylvinylphenyl substituted [2.2]paracyclophane-1,9-diene
Leah Pandiscia, PhD
August 13, 2018
Although carbon quantum dots (CQDs) are of great interest because of cost effectiveness and environmental compatibility with the facile tunability… Continue reading Bottom‐Up Synthesis of Carbon Quantum Dots With High Performance Photo‐ and Electroluminescence
Leah Pandiscia, PhD
August 13, 2018
Due to their unique electronic and photophysical properties, rhenium(I) fac-tricarbonyl complexes of general formula [Re(N^N)(CO)3X]n+ have been arousing constant interest in many… Continue reading Rhenium tricarbonyl complexes with arenethiolate axial ligands
Leah Pandiscia, PhD
August 13, 2018
Most chemotherapeutic drugs commonly suffer from several shortcomings, including the lack of aqueous solubility, limited stability and adverse side effects.… Continue reading A NIR-controlled cage mimicking system for hydrophobic drug mediated cancer therapy
Leah Pandiscia, PhD
August 13, 2018
The photodynamic inactivation of both Gram-positive and Gram-negative bacteria by polycationic silicon (IV) phthalocyanine photosensitizers bearing eight N-methylated pyridyloxy substituents in their periphery and different… Continue reading Octacationic and axially di-substituted silicon (IV) phthalocyanines for photodynamic inactivation of bacteria
Leah Pandiscia, PhD
August 13, 2018
Leah Pandiscia, PhD
August 13, 2018
Three anthraquinone-type multidentate ligands, HL1–3 (HL = 2-R-1H-anthra[1,2-d]imidazole-6,11-dione; HL1: R = (2-pyridyl), HL2; R = (4,6-dimethyl-2-pyridyl), HL3; R = (6-methoxy-2-pyridyl)), were… Continue reading Cobalt complexes with redox-active anthraquinone-type ligands
Leah Pandiscia, PhD
August 13, 2018
A sequence alignment of horse cytochrome c (cyt c) with all known cyts c shows that Leu at position 94 is conserved, except in 14… Continue reading Effect of conservative mutations (L94V and L94I) on the structure and stability of horse cytochrome c
Leah Pandiscia, PhD
August 13, 2018
N-acylhydrazones have been described as responsive compounds to a wide variety of triggers that are able to induce reversible structural… Continue reading Conformational-induced light emission switching of N-acylhydrazone systems
Leah Pandiscia, PhD
August 13, 2018
Leah Pandiscia, PhD
August 13, 2018
Leah Pandiscia, PhD
August 13, 2018
Many studies of drug delivery nano-platforms have explored drug loading affinity or controlled release. The nano-platforms can be influenced by… Continue reading Multilayered controlled drug release silk fibroin nano-film by manipulating secondary structure
Leah Pandiscia, PhD
August 13, 2018
This work demonstrates a methodology for the evaluation of circularly polarized luminescence of a chiral europium(III) (EuIII) complex species in… Continue reading Evaluation of circularly polarized luminescence in a chiral lanthanide ensemble
Leah Pandiscia, PhD
August 13, 2018
Dinuclear Zn2+ complexes with HTQHPN (N,N,N′,N′- tetrakis(2-quinolylmethyl)-2-hydroxy-1,3-propanediamine) derivatives have been prepared, and their pyrophosphate (PPi, P2O7 4−) sensing properties were… Continue reading Pyrophosphate-Induced Intramolecular Excimer Formation in Dinuclear Zinc(II) Complexes with Tetrakisquinoline Ligands
Leah Pandiscia, PhD
August 13, 2018
Leah Pandiscia, PhD
May 22, 2018