Stepwise Thermo-Responsive Amino Acid-Derived Triblock Vinyl Polymers: ATRP Synthesis of Polymers, Aggregation, and Gelation Properties via Flower-Like Micelle Formation

2018 / Materials

Novel thermo-responsive ABA-type triblock copolymers (poly(NAAMen-b-NAGMe240-b-NAAMen), n = 18–72) composed of naturally occurring amino acid–based vinyl polymer blocks such as poly(N-acryloyl-l-alanine methyl… Continue reading Stepwise Thermo-Responsive Amino Acid-Derived Triblock Vinyl Polymers: ATRP Synthesis of Polymers, Aggregation, and Gelation Properties via Flower-Like Micelle Formation

Leah Pandiscia, PhD

Unveiling the Potential of Unfused Bichromophoric Naphthalimide To Induce Cytotoxicity by Binding to Tubulin: Breaks Monotony of Naphthalimides as Conventional Intercalators

2018 / The Journal of Physical Chemistry B

In the development of small-molecule drug candidates, naphthalimide-based compounds hold a very important position as potent anticancer agents with considerable… Continue reading Unveiling the Potential of Unfused Bichromophoric Naphthalimide To Induce Cytotoxicity by Binding to Tubulin: Breaks Monotony of Naphthalimides as Conventional Intercalators

Leah Pandiscia, PhD

An update on the biophysical character of the human eukaryotic elongation factor 1 beta: Perspectives from interaction with elongation factor 1 gamma

2018 / Journal of Molecular Recognition

The β‐subunit of the human eukaryotic elongation factor 1 complex (heEF1β) plays a central role in the elongation step in… Continue reading An update on the biophysical character of the human eukaryotic elongation factor 1 beta: Perspectives from interaction with elongation factor 1 gamma

Leah Pandiscia, PhD

Mechanistic insights into the urea-induced denaturation of kinase domain of human integrin linked kinase

2018 / International Journal of Biological Macromolecules

Integrin-linked kinase (ILK), a ubiquitously expressed intracellular Ser/Thr protein kinase, plays a major role in the oncogenesis and tumour progression. The conformational stability and unfolding… Continue reading Mechanistic insights into the urea-induced denaturation of kinase domain of human integrin linked kinase

Leah Pandiscia, PhD

Flexible versus rigid G‐quadruplex DNA ligands ‐ synthesis of two series of bis‐indole derivatives and comparison of their interactions with G‐quadruplex DNA.

2018 / Chemistry A European Journal

Small molecules that target G‐quadruplex (G4) DNA structures are not only valuable to study G4 biology but also for their… Continue reading Flexible versus rigid G‐quadruplex DNA ligands ‐ synthesis of two series of bis‐indole derivatives and comparison of their interactions with G‐quadruplex DNA.

Leah Pandiscia, PhD

Atom Transfer Radical Addition Catalyzed by Ruthenium–Arene Complexes Bearing a Hybrid Phosphine–Diene Ligand

2018 / Organometallics

The synthesis and characterization of a series of arene ruthenium complexes bearing either (3,5-cycloheptadienyl)diphenylphosphine or (cycloheptyl)diphenylphosphine are reported. Upon irradiation… Continue reading Atom Transfer Radical Addition Catalyzed by Ruthenium–Arene Complexes Bearing a Hybrid Phosphine–Diene Ligand

Leah Pandiscia, PhD

Neutralizing the Charge Imbalance Problem in Eu3+-Activated BaAl2O4Nanophosphors: Theoretical Insights and Experimental Validation Considering K+ Codoping

2018 / ACS Omega

In recent years, rare-earth-doped nanophosphors have attracted great attention in the field of luminescent materials for advanced solid-state lighting and… Continue reading Neutralizing the Charge Imbalance Problem in Eu3+-Activated BaAl2O4Nanophosphors: Theoretical Insights and Experimental Validation Considering K+ Codoping

Leah Pandiscia, PhD

pH-Responsive Fluorescence Change Based on Dynamic Exchange between Emitting Aggregate and Quenching Monomer in Donor-Acceptor Dyes bearing Carboxylic Groups

2018 / European Journal of Organic Chemistry

pH imaging and measurement in biological systems is important because changes in pH are closely related with physiological and pathological… Continue reading pH-Responsive Fluorescence Change Based on Dynamic Exchange between Emitting Aggregate and Quenching Monomer in Donor-Acceptor Dyes bearing Carboxylic Groups

Leah Pandiscia, PhD