Molecular modelling and competition binding study of Br-noscapine and colchicine provide insight into noscapinoid–tubulin binding site

2011 / Journal of Molecular Graphics and Modelling

We have previously discovered the tubulin-binding anti-cancer properties of noscapine and its derivatives (noscapinoids). Here, we present three lines of… Continue reading Molecular modelling and competition binding study of Br-noscapine and colchicine provide insight into noscapinoid–tubulin binding site

Leah Pandiscia, PhD

Entropic stabilization of a deubiquitinase provides conformational plasticity and slow unfolding kinetics beneficial for functioning on the proteasome

2017 / Scientific Reports

Human ubiquitin C-terminal hydrolyase UCH-L5 is a topologically knotted deubiquitinase that is activated upon binding to the proteasome subunit Rpn13.… Continue reading Entropic stabilization of a deubiquitinase provides conformational plasticity and slow unfolding kinetics beneficial for functioning on the proteasome

Leah Pandiscia, PhD

New pyrazolo-quinoline scaffold as a reversible colorimetric fluorescent probe for selective detection of Zn2+ ions and its imaging in live cells

2017 / Journal of Photochemistry and Photobiology A: Chemistry

A simple colorimetric fluorescent chemosensor 1-[5-(2-chloro-6-methylquinolin-3-yl)-3-(2-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one (L) based on pyrazoline has been designed, synthesized and characterized. The sensing properties of L were… Continue reading New pyrazolo-quinoline scaffold as a reversible colorimetric fluorescent probe for selective detection of Zn2+ ions and its imaging in live cells

Leah Pandiscia, PhD

Construction of Novel S/CdS type II heterojunction for photocatalytic H2 production under visible light: the intrinsic positive role of elementary α-S

2017 / Chemical Engineering Journal

Traditional view points that the photocorrosion product sulfur clusters have negative effect on the activity of CdS system. Differently, in… Continue reading Construction of Novel S/CdS type II heterojunction for photocatalytic H2 production under visible light: the intrinsic positive role of elementary α-S

Leah Pandiscia, PhD

Pd cross-coupling reactions in the access to bis-pyrazole and bis-indazole pyridine-based nona-coordinated ligands. Luminescence properties of their lanthanide complexes

2017 / Journal of Photochemistry and Photobiology A: Chemistry

A synthetic approach based on microwave-assisted Pd cross-coupling reactions is developed to obtain two series of push-pull donor-π-conjugated nonadentate coordinating… Continue reading Pd cross-coupling reactions in the access to bis-pyrazole and bis-indazole pyridine-based nona-coordinated ligands. Luminescence properties of their lanthanide complexes

Leah Pandiscia, PhD

Cooperative Effects of o- and m-Methyl Groups on the Intramolecular Charge-Transfer Emission Properties of Dibenzoylmethanatoboron Difluorides

2017 / Photochemical & Photobiological Sciences

The photophysical properties of o-tolyl-, m-tolyl-, and p-xylyl-substituted asymmetric diaroylmethanatoboron difluorides in a mixture of CH2Cl2 and c-C6H12, and in the crystalline state were determined.… Continue reading Cooperative Effects of o- and m-Methyl Groups on the Intramolecular Charge-Transfer Emission Properties of Dibenzoylmethanatoboron Difluorides

Leah Pandiscia, PhD

Simultaneous estimation of scavenging capacities of peach extract for multiple reactive oxygen species by fluorescence fingerprint method

2017 / Food Chemistry

In this study, the potential of using fluorescence fingerprint, also known as fluorescence excitation–emission matrix, for estimating the scavenging capacity… Continue reading Simultaneous estimation of scavenging capacities of peach extract for multiple reactive oxygen species by fluorescence fingerprint method

Leah Pandiscia, PhD