Carlos Morillo
May 16, 2022
In bacteria, the monopolar localization of enzymes and protein complexes can result in a bimodal distribution of enzyme activity between… Continue reading GGDEF domain as spatial on-switch for a phosphodiesterase by interaction with landmark protein HubP
Carlos Morillo
May 13, 2022
Protein-protein and protein-nucleic acid interactions are often considered difficult drug targets because the surfaces involved lack obvious druggable pockets. Cryptic… Continue reading A cryptic pocket in Ebola VP35 allosterically controls RNA binding
Carlos Morillo
May 13, 2022
Recent development of the chemical inhibitors specific to oncogenic KRAS (Kirsten Rat Sarcoma 2 Viral Oncogene Homolog) mutants revives much… Continue reading AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis
Carlos Morillo
May 13, 2022
Carlos Morillo
May 13, 2022
Carlos Morillo
April 18, 2022
Post-translational protein modifications by ubiquitin and ubiquitin-like modifiers regulate many major pathways in the cell. These modifications can be reversed… Continue reading Structural basis for the SUMO protease activity of the atypical ubiquitin-specific protease USPL1
Carlos Morillo
April 18, 2022
In this study, we investigated the axial coordination reaction between pyridine and zinc meso-tetra(4-sulfonatophenyl)porphyrin (ZnTPPS) incorporated in a transparent layered… Continue reading Ultra-sensitive detection of pyridine in water using zinc porphyrin incorporated in a transparent hydrophobic film
Carlos Morillo
April 18, 2022
Photosystem I (PSI) is one of the two photosystems functioning in light-energy harvesting, transfer, and electron transfer in photosynthesis. However,… Continue reading Structure of a tetrameric photosystem I from a glaucophyte alga Cyanophora paradoxa
Carlos Morillo
April 18, 2022
Cyclophilins, or immunophilins, are proteins found in many organisms including bacteria, plants and humans. Most of them display peptidyl-prolyl cis-trans… Continue reading Cyclophilin anaCyp40 regulates photosystem assembly and phycobilisome association in a cyanobacterium
Carlos Morillo
April 18, 2022
Paramagnetic metallohost systems can bind guest molecules and find application as biomimetic catalysts. Due to the presence of the paramagnetic… Continue reading Paramagnetic relaxation enhancement NMR as a tool to probe guest binding and exchange in metallohosts
Carlos Morillo
April 18, 2022
Carbon dots (CDs) are light-emitting nanoparticles that show great promise for applications in biology and medicine due to the ease… Continue reading Revealing the nature of optical activity in carbon dots produced from different chiral precursor molecules
Carlos Morillo
April 18, 2022
Carlos Morillo
March 14, 2022
Transport of lipids across membranes is fundamental for diverse biological pathways in cells. Multiple ion-coupled transporters take part in lipid… Continue reading Evidence for a trap-and-flip mechanism in a proton-dependent lipid transporter
Carlos Morillo
February 24, 2022
Carlos Morillo
February 24, 2022
Carlos Morillo
February 24, 2022
The collagenases of Vibrio species, many of which are pathogens, have been regarded as an important virulence factor. However, there… Continue reading Structure of Vibrio collagenase VhaC provides insight into the mechanism of bacterial collagenolysis
Carlos Morillo
February 1, 2022
Carlos Morillo
February 1, 2022
The relationship between the coordination geometry and photophysical properties of trans-bis[(β-iminomethyl)naphthoxy]platinum(II) was investigated both experimentally and theoretically. A series of… Continue reading Enhancement of Chiroptical Responses of trans-Bis[(β-iminomethyl)naphthoxy]platinum(II) Complexes with Distorted Square Planar Coordination Geometry
Carlos Morillo
February 1, 2022
Carlos Morillo
January 18, 2022
