DJ Tognarelli
April 23, 2020
Self‐controlled synthesis of hyperbranched poly(ether‐ketone)s (HPEKs) were prepared from “A2 + B3” approach by using different monomer solubility in reaction medium. …
Continue reading “Self‐controlled synthesis of hyperbranched poly(ether‐ketone)s from A2 + B3 approach in poly(phosphoric acid)”
DJ Tognarelli
April 23, 2020
DJ Tognarelli
April 23, 2020
DJ Tognarelli
April 23, 2020
A simple, precise and accurate high performance liquid chromatography (HPLC) method was developed for simultaneous quantitative determination of rosiglitazone maleate …
Continue reading “DEVELOPMENT AND VALIDATION OF LC METHOD FOR THE SIMULTANEOUS ESTIMATION OF ROSIGLITAZONE MALEATE AND GLIMEPIRIDE IN PHARMACEUTICAL DOSAGE FORM”
DJ Tognarelli
April 23, 2020
Nowadays agricultural wastes represent an alternative source of renewable raw materials. Different processes can be applied to these alternative materials …
Continue reading “Acid-and base-catalized hydrolyses of corn stalk”
DJ Tognarelli
August 27, 2020
Objective: The objective of this research work was to develop a sensitive, precise, specific, linear and stability-indicating gradient HPLC method …
Continue reading “A VALIDATED GRADIENT STABILITY-INDICATING LC METHOD FOR THE ANALYSIS OF VALSARTAN IN PHARMACEUTICAL DOSAGE FORM”
DJ Tognarelli
August 27, 2020
DJ Tognarelli
April 23, 2020
A simple, selective, rapid, and economical reversed phase high performance liquid chromatogra phy(RPHPLC) method for the determination of doxofylline in …
Continue reading “Development and Validation of Rapid HPLC Method for Determination of Doxofylline in Bulk Drug and Pharmaceutical Dosage Forms”
DJ Tognarelli
August 27, 2020
In the present study, comprehensive stress testing of tenatoprazole was carried out according to ICH guideline Q1A (R2). Tenatoprazole was …
Continue reading “LC–UV and LC–MS evaluation of stress degradation behaviour of tenatoprazole”
DJ Tognarelli
April 23, 2020
To study the effective therapeutic bioavailability of Atazanavir Sulfate (ATV), administered singly or in combination with Ritonavir, a cost effective …
Continue reading “Development, Validation and Statistical Correlation of RP–LC Methods for Determination of Atazanavir Sulfate in Capsule Dosage Form”
DJ Tognarelli
April 23, 2020
The effects of both wood chips addition and contact time on phenolic content, volatile composition, color parameters, and organoleptic character …
Continue reading “Differentiation of Wines Treated with Wood Chips Based on Their Phenolic Content, Volatile Composition, and Sensory Parameters”
DJ Tognarelli
August 27, 2020
Degradation products of itopride formed under different forced conditions have been identified using LC-PDA and LC-MS techniques. Itopride was subjected …
Continue reading “Identification of Forced Degradation Products of Itopride by LC-PDA and LC-MS”
DJ Tognarelli
April 23, 2020
DJ Tognarelli
April 23, 2020
Two sensitive and reproducible methods are described for the quantitative determination of dasatinib in the presence of its degradation products. …
Continue reading “Stability indicating HPTLC and LC determination of dasatinib in pharmaceutical dosage form”
DJ Tognarelli
April 23, 2020
DJ Tognarelli
April 8, 2019
Human gut microbiota senses its environment and responds by releasing metabolites, some of which are key regulators of human health …
Continue reading “Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease”
DJ Tognarelli
April 8, 2019
John Burchell
October 1, 2018
Protein G can be a valuable binding agent for antibodies and immunoglobulins in methods such as immunosensors, chromatographic-based immunoassays, and …
Continue reading “Peak decay analysis and biointeraction studies of immunoglobulin binding and dissociation on protein G affinity microcolumns”
DJ Tognarelli
October 1, 2018
Over 300 chiral drug substances lack official United States Pharmacopeia (USP) methods for the enantiomeric purity determination. Because enantiomeric analysis …
Continue reading “Enantiomeric impurity analysis using circular dichroism spectroscopy with United States Pharmacopeia liquid chromatographic methods”
Leah Pandiscia, PhD
June 20, 2018