Hybrid peptides integrating different functional domains of peptides have many advantages, such as remarkable antimicrobial activity, lower hemolysis and ideal… Continue reading High Specific Selectivity and Membrane-Active Mechanism of Synthetic Cationic Hybrid Antimicrobial Peptides Based on the Peptide FV7
Leah Pandiscia, PhD
July 28, 2017
Carrageenan is a high molecular weight linear sulphated polysaccharide, primarily used in food industry as gelling, thickening, and stabilizing agent.… Continue reading Binding of λ-carrageenan (a food additive) to almond cystatin: An insight involving spectroscopic and thermodynamic approach
Leah Pandiscia, PhD
July 28, 2017
The cationic porphyrin 5,10,15,20-tetrakis (diisopropylguanidine)-21H,23H-porphine “DIGPor” selectively binds to DNA containing O6 -methylguanine (O6 -MeG) and inhibits the DNA repair… Continue reading DNA-Targeted Inhibition of MGMT
Leah Pandiscia, PhD
July 28, 2017
Fish skin is a by-product generated during fish processing. Nowadays the farmed fish, including golden carp, has gained increasing interest… Continue reading Extraction and Characterisation of Collagen from the Skin of Golden Carp (Probarbus Jullieni), a Processing By-Product
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Antimicrobial peptides (AMPs) are small cationic molecules that display antimicrobial activity against a wide range of bacteria, fungi and viruses.… Continue reading Lipid selectivity in novel antimicrobial peptides: implication on antimicrobial and hemolytic activity
Leah Pandiscia, PhD
July 28, 2017
To the best of our knowledge this is the first report on the application of induced circularly polarized luminescence (CPL)… Continue reading Induced Circularly Polarized Luminescence for Revealing DNA Binding with Fluorescent Dyes
Leah Pandiscia, PhD
May 24, 2018
Leah Pandiscia, PhD
July 28, 2017
Oilseeds of the plant family Brassicaceae are important for providing both lipid and protein contents to human nutrition. Cruciferins (12S globulins) are… Continue reading SAXS and other spectroscopic analysis of 12S cruciferin isolated from the seeds of Brassica nigra
Leah Pandiscia, PhD
July 28, 2017
Employing chiral bis-bidentate N-donor ligand, (+)-2,5-bis(4,5-pinene-2-pyridyl) pyrazine (L), as a bridging ligand for Er(dbm)3H2O, and depending on the ratio control… Continue reading Synthesis, crystal structures, photoluminescent, magnetic and chiroptical properties of two homochiral ErIII complexes with different nuclearity
Leah Pandiscia, PhD
July 28, 2017
Aggregation of proteins is a physiological process which contributes to the pathophysiology of several maladies including diabetes mellitus, Huntington’s and… Continue reading Aloe emodin, an anthroquinone from Aloe vera acts as an anti aggregatory agent to the thermally aggregated hemoglobin
Leah Pandiscia, PhD
July 28, 2017
Polyunsaturated lipids are important components of photosynthetic membranes. Xanthophylls are the main photoprotective agents, can assist in protection against light… Continue reading Lipid and carotenoid cooperation-driven adaptation to light and temperature stress in Synechocystis sp. PCC6803
Leah Pandiscia, PhD
July 28, 2017
Two new prenylated isoflavones, pachyloisoflavone A (1), pachyloisoflavone B (2), and a new pterocarpan, pachylobin A (3), together with ten… Continue reading Three new flavonoids from Millettia pachyloba
Leah Pandiscia, PhD
July 28, 2017
An uncharged PNA 15mer sequence formed unimolecular antiparallel G-quadruplex similar to that observed for DNA-TBA. Replacement of ‘tt’ loop regions… Continue reading Critical role of select peptides in the loop region of G-rich PNA in the preferred G-quadruplex topology and stability
Leah Pandiscia, PhD
July 28, 2017
Several retrospective epidemiological reports have indicated an inverse correlation between smoking and development of Parkinson’s disease (PD). This has mostly… Continue reading Nicotine slows down oligomerisation of α-synuclein and ameliorates cytotoxicity in a yeast model of Parkinson’s disease
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
The amyloid fibrils derived from protein and peptide self-assembly have been studied in many diseases. In the present study, in… Continue reading Investigating the inhibitory effects of zinc ions on amyloid fibril formation of hen egg-white lysozyme
Leah Pandiscia, PhD
July 28, 2017
DNA guanine-quadruplexes (G-quadruplexes) are unique DNA structures formed by guanine-rich sequences. The loop regions of G-quadruplexes play key roles in… Continue reading Volumetric contributions of loop regions of G-quadruplex DNA to the formation of the tertiary structure
Leah Pandiscia, PhD
July 28, 2017
Leah Pandiscia, PhD
July 28, 2017
Decellularized extracellular matrix (ECM) derived from tissues and organs are emerging as important scaffold materials for regenerative medicine. Many believe… Continue reading Molecular Assessment of Collagen Denaturation in Decellularized Tissues using a Collagen Hybridizing Peptide
Leah Pandiscia, PhD
July 28, 2017