Found 9617 Results / Page 119 of 481
2020 / Journal of Controlled Release
Metastatic triple-negative breast cancer is one of the most devastating cancer types. Systemic chemotherapy is necessary, but its clinical performance… Continue reading Self-assembling mertansine prodrug improves tolerability and efficacy of chemotherapy against metastatic triple-negative breast cancer
2019 / ACS Applied Materials & Interfaces
A simple and label-free sensing platform with low background based on the chain-displacement triggered self-assembly of Ag NCs was developed… Continue reading Ratiometric Multicolor Analysis of Intracellular MicroRNA Using a Chain Hybrid Substitution-Triggered Self-Assembly of Silver Nanocluster-Based Label-Free Sensing Platform
2020 / LWT
The interaction of Quillaja bark saponin and bovine serum albumin was determined by isothermal titration calorimetry and correlated to the structure, gelation… Continue reading Interaction of Quillaja bark saponin and bovine serum albumin: Effect on secondary and tertiary structure, gelation and in vitro digestibility of the protein
2020 / Food Hydrocolloids
The interaction of Quillaja bark saponin and bovine serum albumin was determined by isothermal titration calorimetry and correlated to the structure, gelation… Continue reading Not sequentially but simultaneously: Facile extraction of proteins and oleosomes from oilseeds
2020 / Chemical Communications
Two pairs of D–A type AIE-active chiral dyes (R-/S-1 and R-/S-2) as chiral emitters doped into nematic liquid crystals (5CB, N-LCs)… Continue reading The amplified circularly polarized luminescence regulated from D–A type AIE-active chiral emitters via liquid crystals system
2020 / Journal of Physical Chemistry B
Wearable sensors for human health, performance, and state monitoring, which have a linear response to the binding of biomarkers found… Continue reading In Silico Discovery and Validation of Neuropeptide-Y-Binding Peptides for Sensors
2020 / Journal of Photochemistry and Photobiology B: Biology
A mono-N-substituted probe L containing a bromosalicylaldehyde pendant arm attached to a tetraazamacrocyclic “tet a” moiety was synthesized via straight forward reaction. The… Continue reading Macrocyclic “tet a” derived colorimetric sensor for the detection of mercury cations and hydrogen sulphate anions and its bio-imaging in living cells
2020 / European Journal of Medicinal Chemistry
Proteolysis-targeting chimera (PROTAC) could selectively degrade target protein and may become a promising strategy for treating estrogen receptor α (ERα)… Continue reading Development of cell-permeable peptide-based PROTACs targeting estrogen receptor α
2020 / Biomacromolecules
Performing biocatalysis in nonaqueous solvents is advantageous as it imparts enhanced solubility to hydrophobic substrates and an ability to increase… Continue reading Neat Ionic liquid and α-Chymotrypsin-Polymer Surfactant Conjugate-Based Biocatalytic Solvent
2020 / Journal of Molecular Structure
In the present investigation, a detailed spectroscopic analysis on the interaction mechanism of 1-Butyl-2,3-dimethylimidazolium tetrafluoroborate [Bdmim][BF4] with human serum albumin… Continue reading Unravelling the distinctive mode of cooperative and independent interaction mechanism of 1-butyl-2,3-dimethylimidazolium tetrafluoroborate ionic liquid with model transport proteins by comprehensive spectroscopic and computational studies
2020 / Carbohydrate Research
Chiron approach was used to acquire optically pure (R)- and (S)-1-(2,6-dimethylphenoxy)propan-2-ol, immediate precursors of (S)- and (R)-mexiletines, respectively. Two different… Continue reading Enantiodivergent syntheses of (+)- and (−)-1-(2,6-dimethylphenoxy)propan-2-ol: A way to access (+)- and (−)-mexiletine from D-(+)-mannitol
2019 / Nature Communications
Coupling of atoms is the basis of chemistry, yielding the beauty and richness of molecules. We utilize semiconductor nanocrystals as… Continue reading Colloidal quantum dot molecules manifesting quantum coupling at room temperature
2020 / Biochemistry
Cyanobacteriochromes (CBCRs) are photoreceptor proteins that photoconvert between two parent states and thereby regulate various biological processes. An intriguing property… Continue reading Red, Orange, Green: Light- and Temperature-Dependent Color Tuning in a Cyanobacteriochrome
2020 / ACS Chemical Biology
Molecular-targeting peptides and mini-proteins are promising alternatives to antibodies in a wide range of applications in bioscience and medicine. We… Continue reading An Immune-Stimulatory Helix–Loop–Helix Peptide: Selective Inhibition of CTLA-4–B7 Interaction
2020 / Journal of Molecular Structure
In this work, three new vanadium complexes are reported. Their synthesis, crystallization and characterization are detailed. The complex (1) [VO(C7H6NO2)2]… Continue reading Synthesis, characterization and structural study of new vanadium complexes with phenolic oxime ligands
2020 / Journal of Sol-Gel Science and Technology
By using La(NO3)3•6H2O, Ca(NO3)2•4H2O, and Mn(CH3COO)2•4H2O as starting raw materials together with methanol, three kinds of La0.67Ca0.33MnO3 (LCMO) solutions, denoted as… Continue reading Fabrication and characterization of micropatterned La0.67Ca0.33MnO3 films via the UV assisted photosensitive solution deposition method
2019 / Nature Communications
Enzyme biosensors are useful tools that can monitor rapid changes in metabolite levels in real-time. However, current approaches are largely… Continue reading An artificial metalloenzyme biosensor can detect ethylene gas in fruits and Arabidopsis leaves
2020 / International Journal of Biological Macromolecules
Impact of high-power sonication (HPS) as pretreatment in extraction and some physicochemical properties of proteins from soybean flakes, flour of… Continue reading Effect of high-power sonication pretreatment on extraction and some physicochemical properties of proteins from chickpea, kidney bean, and soybean☆
2020 / Journal of Structural Biology
In bacteria, nucleoid associated proteins (NAPs) take part in active chromosome organization by supercoil management, three-dimensional DNA looping and direct… Continue reading Structural and DNA binding properties of mycobacterial integration host factor mIHF
2020 / Biochimie
Type 2 diabetes mellitus is a disease characterized by the formation of amyloid fibrillar deposits consisting mainly in human islet… Continue reading The flanking peptides issue from the maturation of the human islet amyloid polypeptide (hIAPP) slightly modulate hIAPP-fibril formation but not hIAPP-induced cell death
