Protein macrocyclization represents a very efficient strategy to increase the stability of protein tertiary structures. Here, we describe a panel… Continue reading In Situ Cyclization of Proteins (INCYPRO): Cross-Link Derivatization Modulates Protein Stability
Leah Pandiscia, PhD
March 24, 2020
A series of carbazole‐based boron dipyrromethenes (BODIPYs) 2 a–g bearing binaphthyl units have been synthesized by the Et2AlCl‐mediated reaction of the corresponding BODIPY… Continue reading Synthesis and Chiroptical Properties of Chiral Carbazole‐Based BODIPYs
Leah Pandiscia, PhD
March 24, 2020
Antimicrobial resistance stimulates the search for antimicrobial forms that may be less subject to acquired resistance. Here we report a… Continue reading Engineering Chirally Blind Protein Pseudocapsids into Antibacterial Persisters
Leah Pandiscia, PhD
March 24, 2020
Ubiquicidin (UBI)/ribosomal protein S30 (RS30) is an intracellular protein with antimicrobial activities against various pathogens. UBI (29–41) and UBI (31–38)… Continue reading Ubiquicidin-Derived Peptides Selectively Interact with the Anionic Phospholipid Membrane
Leah Pandiscia, PhD
March 24, 2020
Chloroacetic acid (CAA), one of typical disinfection by-products (DBPs), has attracted considerable concerns for its biological safety. Antioxidant enzyme catalase… Continue reading In vitro toxicity and molecular interacting mechanisms of chloroacetic acid to catalase
Leah Pandiscia, PhD
June 29, 2020
Leah Pandiscia, PhD
March 24, 2020
A pair of stable chiral coordination compounds {[Zn (D-hpg) (bpe)]⋅(NO3)⋅(C2H6O)}n 1-D, {[Zn (L-hpg) (bpe)]⋅(NO3)⋅(C2H6O)}n 1-L (D-Hhpg = D-(−)-4-Hydroxyphenylglycine, L-Hhpg = L-(+)-4-Hydroxyphenylglycine, bpe = 1,2-bis(4-pyridyl)ethane) have been successfully synthesized. Their structures… Continue reading A pair of stable Zn(II) enantiomeric coordination compounds: synthesis, crystal structures and luminescent recognition properties
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
New sesquiterpene quinones, metachromins X (1) and Y (2), together with the known metachromins C (3), J (4), and T… Continue reading Metachromins X and Y from a marine sponge Spongia sp. and their effects on cell cycle progression
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Biomedical applications require substrata that allow for the grafting, colonization and control of eukaryotic cells. Currently available materials are often… Continue reading Carbon-nanotube reinforcement of DNA-silica nanocomposites yields programmable and cell-instructive biocoatings
Leah Pandiscia, PhD
March 24, 2020
Separating racemates is still a great challenge for their similarity in chemical structures and physicochemical properties. Despite exhibiting a significant… Continue reading Toward High-Efficient Chiral Separation Using Hierarchically Porous HROP@Silica-Gel-Sheet Composite
Leah Pandiscia, PhD
March 24, 2020
Multidomain Peptide (MDP) hydrogels are nanofibrous materials with many potential biomedical applications. The peptide sequence design of these materials offers… Continue reading Chemical functionality of multidomain peptide hydrogels governs early host immune response
Leah Pandiscia, PhD
March 24, 2020
Racemic 1-phenylethylamine was converted to bidentate Schiff base ligand by condensing with imidazole-2-carboxaldehyde (rac-L2). The reaction between Ni(II)(ClO4)2, rac-L2 and another… Continue reading Chiral resolution of 1-phenylethylamine in Schiff base form within a mixed ligand complex of Ni(II)
Leah Pandiscia, PhD
March 24, 2020
A new fluorescence receptor 2-(diethylamino)-N-(quinolin-8-yl) acetamide (L) was synthesized by simple reaction condition. The ligand HL is highly selective and sensitive towards… Continue reading An “Off-On-Off” type fluorescent chemosensor for the relay detection of Zn2+ and H2PO4− in aqueous environment
Leah Pandiscia, PhD
March 24, 2020
Chiral-induced spin selectivity (CISS) occurs when the chirality of the transporting medium selects one of the two spin ½ states… Continue reading Spin-dependent charge transport through 2D chiral hybrid lead-iodide perovskites
Leah Pandiscia, PhD
March 24, 2020
Six triruthenium complexes (1–6) ([Ru3O(CH3COO)6(L)3]PF6, L = quinazoline (qui) (complex 1), 5-nitroisoquinoline (5-nitroiq) (complex 2), 5-bromoisoquinoline (5-briq) (complex 3), isoquinoline (iq) (complex 4), 5-aminoisoquinoline (5-amiq) (complex 5),… Continue reading Anticancer activity and DNA interaction of ruthenium acetate clusters bearing azanaphthalene ancillary ligands
Leah Pandiscia, PhD
March 24, 2020
Gene CA_C0816 codes for a serine hydrolase protein from Clostridium acetobutylicum (ATCC 824) a member of hormone-sensitive lipase of lipolytic family IV.… Continue reading Biochemical characterization of an esterase from Clostridium acetobutylicum with novel GYSMG pentapeptide motif at the catalytic domain
Leah Pandiscia, PhD
March 24, 2020
Leah Pandiscia, PhD
March 24, 2020
Supramolecular hydrogels self-assembled from short peptides have shown great potential as biomimetic extracellular matrices with controllable properties designed at the… Continue reading Dipeptide Self-Assembled Hydrogels with Tunable Mechanical Properties and Degradability for 3D Bioprinting
Leah Pandiscia, PhD
March 24, 2020