KnowledgeBase Articles Archive

Localized controlled release of bevacizumab and doxorubicin by thermo-sensitive hydrogel for normalization of tumor vasculature and to enhance the efficacy of chemotherapy

2019 / International Journal of Pharmaceutics

In a malignant tumor, overexpression of pro-angiogenic factors like vascular endothelial growth factor (VEGF) provokes the production of pathologic vascular… Continue reading Localized controlled release of bevacizumab and doxorubicin by thermo-sensitive hydrogel for normalization of tumor vasculature and to enhance the efficacy of chemotherapy

Substituent dependent selectivity of fluorescent chemosensors derived from coumarin for biologically relevant DNA structures and anions

2020 / Sensors and Actuators B: Chemical

In this study, we describe facile synthesis of a series of coumarin appended Schiff base chemosensors for the detection of… Continue reading Substituent dependent selectivity of fluorescent chemosensors derived from coumarin for biologically relevant DNA structures and anions

Green synthesis of silver nanostructures with amino acid-modified Pluronic F127 for antibacterial applications

2019

The aim of this work was to evaluate the use of amino acid-functionalized Pluronic F127 derivatives in the synthesis of… Continue reading Green synthesis of silver nanostructures with amino acid-modified Pluronic F127 for antibacterial applications

Entrapment in micellar assemblies switches the excimer population of potential therapeutic luminophore azapodophyllotoxin

2019 / Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy

Azapodophyllotoxin is a new class of anti-tumor agent with brilliant therapeutic activity and understanding its physicochemical nature in bio-mimetic microenvironments… Continue reading Entrapment in micellar assemblies switches the excimer population of potential therapeutic luminophore azapodophyllotoxin

Carbon dots-incorporated pH-responsive agarose-PVA hydrogel nanocomposites for the controlled release of norfloxacin drug

2019 / Polymer Bulletin

Several hydrogels-based delivery systems are designed and studied in order to meet the requirements in biomedical fields. Herein, the possibility… Continue reading Carbon dots-incorporated pH-responsive agarose-PVA hydrogel nanocomposites for the controlled release of norfloxacin drug

Synthesis and properties of liquid pyrazine dyes

2019 / Dyes and Pigments

Six 2,5-diamino-3,6-dicyanopyrazine dyes with medium to long length alkyl chains on their amino groups were newly synthesised and their fundamental… Continue reading Synthesis and properties of liquid pyrazine dyes

Fluorescence Enhancement of Aromatic Macrocycles by Lowering Excited Singlet State Energies

2019 / The Journal of Organic Chemistry

A series of cyclo-meta-phenylene congeners with a variation of interphenylene bridges was synthesized by adopting concise synthetic routes to investigate… Continue reading Fluorescence Enhancement of Aromatic Macrocycles by Lowering Excited Singlet State Energies

Engineering Secretory Amyloids for Remote and Highly Selective Destruction of Metastatic Foci

2019 / Advanced Materials

Functional amyloids produced in bacteria as nanoscale inclusion bodies are intriguing but poorly explored protein materials with wide therapeutic potential.… Continue reading Engineering Secretory Amyloids for Remote and Highly Selective Destruction of Metastatic Foci

EPR and MCD spectra of the nitrogenase M cluster precursor suggest sulfur migration upon oxidation: A proposal for substrate and inhibitor binding

2019 / ChemBioChem

The active site of the nitrogen fixing enzyme, Mo‐nitrogenase, is the M cluster ([MoFe7S9C·R‐homocitrate]), also known as the FeMo cofactor… Continue reading EPR and MCD spectra of the nitrogenase M cluster precursor suggest sulfur migration upon oxidation: A proposal for substrate and inhibitor binding

Exploring the interactions of a Tb(III)–quercetin complex with serum albumins (HSA and BSA): spectroscopic and molecular docking studies

2019 / Luminescence

Serum albumins (human serum albumin (HSA) and bovine serum albumin (BSA), two main circulatory proteins), are globular and monomeric macromolecules… Continue reading Exploring the interactions of a Tb(III)–quercetin complex with serum albumins (HSA and BSA): spectroscopic and molecular docking studies

In-situ synthesis of metal nanoparticles@metal−organic frameworks: Highly effective catalytic performance and synergistic antimicrobial activity

2019 / Journal of Hazardous Materials

M-NP@Zn-BIF (M-NP = Ag or Cu nanoparticle; Zn-BIF is a zinc-based boron imidazolate framework, Zn2(BH(2-mim)3)2(obb); 2-mim = 2-methylimidazole; obb = 4,4′-oxybis(benzoate)) composites were successfully in-situ synthesized by utilizing… Continue reading In-situ synthesis of metal nanoparticles@metal−organic frameworks: Highly effective catalytic performance and synergistic antimicrobial activity

Hydrogen bond analysis of a third order nonlinear optical crystal, 2-amino-5-bromopyridinium benzilate, using structural and computational characterizations

2020 / Journal of Molecular Structure

The molecular structure of a proton transfer organic material, 2-amino-5-bromopyridinium benzilate crystal, grown by slow-evaporation solution growth technique has been… Continue reading Hydrogen bond analysis of a third order nonlinear optical crystal, 2-amino-5-bromopyridinium benzilate, using structural and computational characterizations

Evaluation of Charge-Regulated Supramolecular Copolymerization to Tune the Time Scale for Oxidative Disassembly of β-Sheet Comonomers

2019 / Macromolecular Rapid Communications

A multistimuli-responsive supramolecular copolymerization is reported. The copolymerization is driven by hydrogen bond encoded β-sheet-based charge co-assembly into 1D nanorods… Continue reading Evaluation of Charge-Regulated Supramolecular Copolymerization to Tune the Time Scale for Oxidative Disassembly of β-Sheet Comonomers

A new aquatic pathogen inhibitor produced by the marine fungus Aspergillus sp. LS116

2019 / Aquaculture

In this study, a fungal strain LS116 with antibacterial activity against aquatic pathogen Vibrio harveyi was screened out from sponge-associated fungi by… Continue reading A new aquatic pathogen inhibitor produced by the marine fungus Aspergillus sp. LS116

Layer by Layer Antimicrobial Coatings Based on Nafion, Lysozyme, and Chitosan

2019 / Nanomaterials

The study focuses on the development of a new family of layer-by-layer coatings comprising Nafion, lysozyme and chitosan to address… Continue reading Layer by Layer Antimicrobial Coatings Based on Nafion, Lysozyme, and Chitosan

Divalent Cations and Lipid Composition Modulate Membrane Insertion and Cancer-Targeting Action of pHLIP

2019 / Journal of Molecular Biology

The pH-Low Insertion Peptide (pHLIP) has emerged as an important tool for targeting cancer cells; it has been assumed that… Continue reading Divalent Cations and Lipid Composition Modulate Membrane Insertion and Cancer-Targeting Action of pHLIP

Synthesis and Hierarchical Self‐Assembly of Diphenylalanine‐Based Homopolymer and Copolymers By RAFT Polymerization

2019 / Journal of Polymer Science Part A: Polymer Chemistry

Dipeptide diphenylalanine has attracted significant research interests because of its ability to self‐assemble into various nanostructures such as nanotubes, nanowires,… Continue reading Synthesis and Hierarchical Self‐Assembly of Diphenylalanine‐Based Homopolymer and Copolymers By RAFT Polymerization

A cystine-based dual chemosensor for fluorescent-colorimetric detection of CN− and fluorescent detection of Fe3+ in aqueous media: Synthesis, spectroscopic, and DFT studies

2019 / Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy

A new dual-responsive chiral cystine based chemosensor, Cys(cou)2, has been designed and characterized by 1H NMR, 13C NMR, FT-IR, UV–vis as well… Continue reading A cystine-based dual chemosensor for fluorescent-colorimetric detection of CN− and fluorescent detection of Fe3+ in aqueous media: Synthesis, spectroscopic, and DFT studies

Structure of the Human ACP-ISD11 Heterodimer

2019 / Biochemistry

In recent years, the mammalian mitochondrial protein complex for iron–sulfur cluster assembly has been the focus of important studies. This… Continue reading Structure of the Human ACP-ISD11 Heterodimer

A comprehensive study of opto-electrical and nonlinear properties of Cu@CdS thin films for optoelectronics

2020 / Chinese Journal of PHysics

Good quality cadmium sulfide (CdS) thin films were deposited on substrates of glass with different Cu concentrations using a sophisticated… Continue reading A comprehensive study of opto-electrical and nonlinear properties of Cu@CdS thin films for optoelectronics

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