Found 9617 Results / Page 132 of 481
2020 / Journal of Molecular Structure
The synthesis and conformational preferences of a novel chiral macrocyclic polyimine possessing spiro carbon atoms is described. The key feature… Continue reading Axial chirality inversion at a spiro carbon leads to efficient synthesis of polyimine macrocycle
2019 / The Journal of Physical Chemistry B
Conformational equilibria in the protein denatured state have key roles regulating folding, stability, and function. The extent of conformational bias… Continue reading Impact of Heat on Coil Hydrodynamic Size Yields the Energetics of Denatured State Conformational Bias
2020 / Colloids and Surfaces B: Biointerfaces
This manuscript presents a novel bioanalytical approach for the selective ratiometric fluorescent sensing of enzymatic activity of the alkaline phosphatase… Continue reading Mimicking biological process to detect alkaline phosphatase activity using the vitamin B6 cofactor conjugated bovine serum albumin capped CdS quantum dots
2019 / Journal of Natural Products
An ethanolic extract of Anneslea fragrans leaves showed potent preferential cytotoxicity against PANC-1 human pancreatic cancer cells under a nutrient-deprived condition, with… Continue reading Chemical Constituents of Anneslea fragrans and Their Antiausterity Activity against the PANC-1 Human Pancreatic Cancer Cell Line
2019 / Macromolecules
Switching the macromolecular helicity of poly(phenylacetylene)s (PPAs) through external achiral stimuli provides convenient possibilities in designing smart chiral materials. Herein,… Continue reading Thermoresponsive Dendronized Poly(phenylacetylene)s Showing Tunable Helicity
2019 / ACS Omega
Novel tetracyanidonitridorhenium(V) complexes with five-membered N-heteroaromatic ligands, (PPh4)2[ReN(CN)4L] [L = imidazole (Him) (2), 1-methylimidazole (Mim) (3), and pyrazole (pyz) (4)]… Continue reading Synthesis and Photoluminescence of Tetracyanidonitridorhenium(V) Complexes with Five-Membered N-Heteroaromatic Ligands and Photoluminescence-Intensity Change
2020 / Biomaterials
Supramolecular hydrogel delivery systems have attracted widely attention owing to incorporating various therapeutic agents in carriers to decrease unpredictable toxicities,… Continue reading Dual-functional guanosine-based hydrogel integrating localized delivery and anticancer activities for cancer therapy
2019 / biomolecules
Amyloids represent protein fibrils with a highly ordered spatial structure, which not only cause dozens of incurable human and animal… Continue reading [PDF] Two Novel Amyloid Proteins, RopA and RopB, from the Root Nodule Bacterium Rhizobium leguminosarum
2020 / Colloids and Surfaces A: Physicochemical and Engineering Aspects
The advantage of using Langmuir–Blodgett (LB) method in assembling thin films is mainly the effective controlling the orientation of the… Continue reading Pyrene-based amphiphile regulated C60 aggregation in monolayers and Langmuir–Blodgett films
2019 / Nano Letters
Organic chiral materials have brought attention due to their potential application in the area of spin-optics and optoelectronics. Compared with… Continue reading Spin–Photon Coupling in Organic Chiral Crystals
2019 / Scientific Reports
We have studied the excited-state dynamics for the i-motif form of cytosine chains (dC)10, using the ultrafast fluorescence up-conversion technique.… Continue reading Exciton Absorption and Luminescence in i-Motif DNA
2019 / Journal of Biological Chemistry
Bacillus subtilis PdaC (BsPdaC) is a membrane-bound, multidomain peptidoglycan N-deacetylase acting on N-acetylmuramic (Mur-NAc) residues and conferring lysozyme resistance to… Continue reading Structure-function relationships underlying the dual N-acetylmuramic and N-acetylglucosamine specificities of the bacterial peptidoglycan deacetylase PdaC
2019 / Marine Drugs
We demonstrated the hitherto unknown property of the mycotoxin sterigmatocystin (STC) to provide homogeneous solutions in aqueous medium by forming… Continue reading Unique Aggregation of Sterigmatocystin in Water Yields Strong and Specific Circular Dichroism Response Allowing Highly Sensitive and Selective Monitoring of Bio-Relevant Interactions
2020 / Microchemical Journal
Simeprevir (SMV) is a newly introduced, powerful hepatitis C antiviral agent. We hereby introduce a validated rapid, sensitive and straight… Continue reading Sensitive spectrofluorimetric assay based on micelle enhanced protocol for the determination of hepatitis C antiviral agent (simeprevir): Application to dosage form and human plasma
2019 / Science Advances
Liquid-liquid phase separation (LLPS) facilitates the formation of functional membraneless organelles and recent reports have linked this phenomenon to protein… Continue reading Low-complexity domain of U1-70K modulates phase separation and aggregation through distinctive basic-acidic motif
2019 / Scientific Reports
Acyl carrier proteins (ACPs) are essential to the production of fatty acids. In some species of marine bacteria, ACPs are… Continue reading Artificial covalent linkage of bacterial acyl carrier proteins for fatty acid production
2019 / Fitoterpia
A new isoiphionane sesquiterpene, named (3S, 5S, 7S, 10R)-3, 11-dihydroxyisoiphion-4-one (1), two new phloroglucinol glycosides, named eucalglobuside A (2) and… Continue reading Tyrosinase inhibitors from the leaves of Eucalyptus globulus
2019 / Journal of Molecular Liquids
As an amide fungicide, fenhexamid has been extensively used to control botrytis and sclerotinia as well as antagonize the resistant… Continue reading In vitro exploration of interaction behavior between calf thymus DNA and fenhexamid with the help of multi-spectroscopic methods and molecular dynamics simulations
2019 / Biochimica et Biophysica Acta (BBA) - Biomembranes
Host defense peptides selectively kill bacterial and cancer cells (including those that are drug-resistant) by perturbing the permeability of their… Continue reading Aggregation determines the selectivity of membrane-active anticancer and antimicrobial peptides: The case of killerFLIP
2019 / Biochemical Pharmacology
Endothelial dysfunction predisposing to cardiovascular diseases is defined as an imbalance in the production of vasodilating factors, such as nitric… Continue reading S-Nitrosothiols as potential therapeutics to induce a mobilizable vascular store of nitric oxide to counteract endothelial dysfunction
