Leah Pandiscia, PhD
April 9, 2019
Even though the bis‐lactam peptide stapling with the [i, i + 7] and the [i, i + 11] systems has been known to be… Continue reading Bis‐Lactam Peptide [i, i + 4]‐Stapling
Leah Pandiscia, PhD
April 9, 2019
Leah Pandiscia, PhD
April 9, 2019
Characterization of small oligomers formed at an early stage of amyloid formation is critical to understanding molecular mechanism of pathogenic… Continue reading Transthyretin Aggregation Pathway toward the Formation of Distinct Cytotoxic Oligomers
Leah Pandiscia, PhD
April 9, 2019
Leah Pandiscia, PhD
April 9, 2019
Many organisms possess the ability to produce metal-binding proteins to absorb cadmium. Metallothioneins, an important family of cysteine-rich metal-binding proteins,… Continue reading Purification and Characterization of a Cadmium-Binding Protein from Lentinula edodes
Leah Pandiscia, PhD
April 9, 2019
Peptide-mediated routes to the synthesis of plasmonic nanoparticles have been drawing increasing attention for the development of chiroptically active nanoscale… Continue reading In Situ Generation of Chiroptically-Active Gold-Peptide Superstructures Promoted by Iodination
Leah Pandiscia, PhD
April 9, 2019
Leah Pandiscia, PhD
April 9, 2019
Leah Pandiscia, PhD
April 9, 2019
We report the assembly behavior of an antimitotic cell penetrating peptide (CPP) bound with membrane and in solution using experimental… Continue reading Self-Assembly of Antimitotic Peptide at Membranes: Computational and Experimental Investigation
Leah Pandiscia, PhD
April 9, 2019
Leah Pandiscia, PhD
April 9, 2019
Although separation of single-walled carbon nanotubes (SWCNTs) according to their helicity and handedness has been attracting tremendous interest recently, exploration… Continue reading Enantiomers of Single Chirality Nanotube as Chiral Recognition Interface for Enhanced Electrochemical Chiral Analysis
Leah Pandiscia, PhD
April 9, 2019
It has been extremely challenging to detect protein structures with a dynamic core, such as dry molten globules, that remain… Continue reading Slow Motion Protein Dance Visualized Using Red-Edge Excitation Shift of a Buried Fluorophore
Leah Pandiscia, PhD
April 9, 2019
Leah Pandiscia, PhD
April 9, 2019
A pair of novel enantiomeric benzophenone-hemiterpene adducts, (+)-cytorhizophin A (1a) and (−)-cytorhizophin A (1b) as well as cytorhizophin B (2),… Continue reading Cytorhizophins A and B, benzophenone-hemiterpene adducts from the endophytic fungus Cytospora rhizophorae
Leah Pandiscia, PhD
April 9, 2019
In the present work, three kinds of reducing sugars: glucose, galactose, and mannose, are applied to horseradish peroxidase (HRP)-catalyzed hydrogelation… Continue reading Horseradish peroxidase-catalyzed hydrogelation consuming enzyme-produced hydrogen peroxide in the presence of reducing sugars
Leah Pandiscia, PhD
April 9, 2019
β-Propeller proteins form one of the largest families of protein structures, with a pseudo-symmetrical fold made up of subdomains called… Continue reading Computational design of symmetrical eight-bladed β-propeller proteins
Leah Pandiscia, PhD
April 9, 2019
Lepidopteran male moths have an extraordinarily sensitive olfactory system that is capable of detecting and responding to minute amounts of… Continue reading Structure and Function Studies of Asian Corn Borer Ostrinia furnacalis Pheromone Binding Protein2
Leah Pandiscia, PhD
April 9, 2019
Leah Pandiscia, PhD
April 9, 2019
Thermo-alkalophilic bacterium, Geobacillus thermoleovorans secrets many enzymes including a 43 kDa extracellular lipase. Significant thermostability, organic solvent stability and wide substrate preferences for hydrolysis drew our attention to solve… Continue reading X-ray structure and characterization of a thermostable lipase from Geobacillus thermoleovorans
Leah Pandiscia, PhD
April 9, 2019