The functions of biomacromolecules are largely governed by their stereostructure (i.e., configuration and conformation). Therefore, detailed understanding of their structural… Continue reading Studying the stereostructures of biomolecules and their analogs by vibrational circular dichroism
Leah Pandiscia, PhD
November 2, 2018
The chemistry of artificial nucleosides is associated with the difficulties in the characterization of the stereochemistry and conformation of their… Continue reading Stereochemistry (and Conformation) of Nucleosides and Their Synthetic Precursors by Vibrational Circular Dichroism.
Leah Pandiscia, PhD
November 2, 2018
Enantioselectivity in environmental behavior and toxic effect of chiral pesticides has been received much attention. In this study, enantioselective bioactivity… Continue reading Chiral triazole fungicide tebuconazole: enantioselective bioaccumulation, bioactivity, acute toxicity, and dissipation in soils
Leah Pandiscia, PhD
November 2, 2018
Chiral herbicides consist of two or more enantiomers, which usually differ in their biological properties and behave enantioselectively in biochemical process. Scant studies have… Continue reading Enantiomeric characterization of herbicide lactofen: Enantioseparation, absolute configuration assignment and enantioselective activity and toxicity
Leah Pandiscia, PhD
November 2, 2018
Ferrocene with its aromaticity and facile redox properties is an attractive moiety to be incorporated into functional moieties. Medicinal applications… Continue reading Synthesis and structure analysis of ferrocene‐containing pseudopeptide
Leah Pandiscia, PhD
November 2, 2018
Temperature-dependent vibrational circular dichroism (VCD) measurements were performed in situ during the solgel transformation of a chiral low-molecular weight gelator,… Continue reading In-Situ Monitoring of Sol-Gel Transition by Temperature-dependent VCD Method: Signal Enhancement Induced by Gelation
Leah Pandiscia, PhD
November 2, 2018
Vibrational circular dichroism spectra (VCD) in the mid‐IR region and electronic circular dichroism (ECD) spectra for three carnitine derivatives in… Continue reading Vibrational Circular Dichroism (VCD) Reveals Subtle Conformational Aspects and Intermolecular Interactions in the Carnitine Family
Leah Pandiscia, PhD
November 2, 2018
Leah Pandiscia, PhD
November 2, 2018
As reported in our previous work, banded spherulites of isotactic poly(2-vinylpyridine) (iP2VP) with preferred handedness of twisted lamellae can be… Continue reading Directed crystallization of isotactic poly(2-vinylpyridine) for preferred lamellar twisting by chiral dopants
Leah Pandiscia, PhD
November 2, 2018
Here, we report the mechanisms of chiral transfer at various length scales in the self-assembly of enantiomeric chiral block copolymers… Continue reading Transfer of Chirality from Molecule to Phase in Self-Assembled Chiral Block Copolymers
Leah Pandiscia, PhD
November 2, 2018
Readily available chiral trianglimine and their (poly)oxygenated congeners represent a unique class of macrocyclic rigid compounds optimal for testing electronic… Continue reading Electronic and vibrational exciton coupling in oxidized trianglimines
Leah Pandiscia, PhD
November 2, 2018
The aim of the present work was to test various chiroptical techniques, including in particular the in situ dirhodium methodology,… Continue reading Chirality sensing of bioactive compounds with amino alcohol unit via circular dichroism
Leah Pandiscia, PhD
November 2, 2018
Leah Pandiscia, PhD
November 2, 2018
Incensole 1 and its acetate 2, found in incense, demonstrate interesting biological activities. Incensole acetate 2 was prepared on a large scale by employing the Paul… Continue reading 5-epi-Incensole: synthesis, X-ray crystal structure and absolute configuration by means of ECD and VCD studies in solution and solid state
Leah Pandiscia, PhD
November 2, 2018
Three β‐keto sulfoxides (1–3) were synthesized in enantiopure form and investigated by means of circular dichroism (CD) spectroscopy, both in… Continue reading Stereochemical analysis of β‐keto sulfoxides by circular dichroism
Leah Pandiscia, PhD
November 2, 2018
The combination of Fourier transform infrared (FT-IR) microspectroscopywith a thermal analyzer was applied to quickly investigate the solid-state ion-exchange reaction of metoclopramide HCl monohydrate… Continue reading Thermal FT-IR microspectroscopy for rapid detection of solid-state ion-exchange reaction between metoclopramide HCl monohydrate and potassium bromide
Leah Pandiscia, PhD
November 2, 2018
The impact of thermal stress on indomethacin (IMC)–nicotinamide (NIC) cocrystal formation with or without neat cogrinding was investigated using differential… Continue reading An Investigation of Indomethacin?Nicotinamide Cocrystal Formation Induced by Thermal Stress in the Solid or Liquid State
Leah Pandiscia, PhD
November 2, 2018
We have measured temporal change of infrared reflection spectrum of ionic phase of tetrathiafulvalene-p-chloranil (TTF-CA) crystal induced by 10 ns… Continue reading Time-resolved Fourier-transform infrared reflection study on photoinduced phase transition of tetrathiafulvalene-p-chloranil crystal
Leah Pandiscia, PhD
November 2, 2018
Several series of Al- and P-doped ZnO thin films have been deposited with atomic layer deposition at different temperatures using… Continue reading Electron doping of ALD-grown ZnO thin films through Al and P substitutions
Leah Pandiscia, PhD
November 2, 2018
We studied colon carcinogenesis using Fourier-transforminfrared (FT-IR) microspectroscopy, an evolvingmethod that llows the nondestructive assessment of the chemical composition of… Continue reading FT-IR Microspectroscopy of Mouse Colon Tissues : Insight into the Chemistry of Carcinogenesis and Diagnostic Potential
Leah Pandiscia, PhD
November 2, 2018