The acylphosphatase from Sulfolobus solfataricus (Sso AcP) is a globular protein able to aggregate in vitro from a native-like conformational ensemble without the need for a transition across the… Continue reading Direct Conversion of an Enzyme from Native-like to Amyloid-like Aggregates within Inclusion Bodies
Leah Pandiscia, PhD
October 11, 2018
The interaction of Ribonuclease A (RNase A) with the bile salt, sodium deoxycholate (NaDC) is meticulously investigated using various spectroscopic… Continue reading Stepwise unfolding of Ribonuclease A by a biosurfactant
Leah Pandiscia, PhD
October 11, 2018
Reversible shape switching due to external stimuli is an attractive property for the control of molecular features. Hence, we aimed… Continue reading Photocontrol over Molecular Shape: Synthesis and Photochemical Evaluation of Glycoazobenzene Macrocycles
Leah Pandiscia, PhD
October 11, 2018
The mechanisms of the toxicity of Sudan dyes to the key antioxidant enzyme catalase (CAT) were investigated by spectroscopic methods,… Continue reading Comparison of the toxicity of the dyes Sudan II and Sudan IV to catalase
Leah Pandiscia, PhD
October 11, 2018
Ciprofloxacin (CPFX) and enrofloxacin (ENFX) are 2 representatives of widely used fluoroquinolones (FQs) with many human and veterinary applications. The… Continue reading Experimental and computational characterization on the binding of two fluoroquinolones to bovine hemoglobin
Leah Pandiscia, PhD
October 11, 2018
Myocardial infarction remains one of the top leading causes of death in the world and the damage sustained in the… Continue reading Angiogenic peptide nanofibers repair cardiac tissue defect after myocardial infarction
Leah Pandiscia, PhD
October 11, 2018
One new and six known pyrrolizidine alkaloids (1–7) were isolated from the 70% ethanol extract of the aerial parts of Heliotropium… Continue reading Anti-inflammatory of pyrrolizidine alkaloids from Heliotropium digynum
Leah Pandiscia, PhD
October 11, 2018
Leah Pandiscia, PhD
October 11, 2018
Changes in the microenvironment of Trp in lysozyme are one of the key factors in the fibrillation process. Gallic acid… Continue reading Probing the role of ortho-dihydroxy groups on lysozyme fibrillation
Leah Pandiscia, PhD
October 11, 2018
Intrinsically disordered proteins (IDPs) lack stable secondary and tertiary structureunder physiological conditions in the absence of their biological partners and thus… Continue reading Interfacial Properties of NTAIL, an Intrinsically Disordered Protein
Leah Pandiscia, PhD
October 11, 2018
Leah Pandiscia, PhD
October 11, 2018
Leah Pandiscia, PhD
October 11, 2018
Drug-resistant microorganism infections cause serious disease and can lead to mortality and morbidity. In particular, Staphylococcus aureus induces pyrogenic and toxigenic infections,… Continue reading Anti-endotoxin mechanism of the KW4 peptide in inflammation in RAW 264.7 cells induced by LTA and drug-resistant Staphylococcus aureus 1630
Leah Pandiscia, PhD
October 11, 2018
Our effort has been made to develop the As(III) switch – on fluorescence biosensor based on MoS2 nanosheets. The simple sensing… Continue reading MoS2 nanosheets as an effective fluorescent quencher for successive detection of arsenic ions in aqueous system
Leah Pandiscia, PhD
October 11, 2018
In the present work, the interaction of phosphorous heterocycle (PH) with calf thymus DNA (CTDNA) has been studied using spectroscopy… Continue reading Spectroscopic Evidence of Phosphorous Heterocycle–DNA Interaction and its Verification by Docking Approach
Leah Pandiscia, PhD
October 11, 2018
A new lectin from the marine sponge Chondrilla caribensis (CCL) was isolated by affinity chromatography in Sepharose 6B media. CCL is a homotetrameric protein formed by subunits of… Continue reading Antibacterial activity of a new lectin isolated from the marine sponge Chondrilla caribensis
Leah Pandiscia, PhD
October 11, 2018
Zingiber officinale Roscoe (Ginger) is a widely used traditional medicinal plant (for different ailments such as arthritis, constipation, and hypertension). This… Continue reading Isolation and initial structural characterization of a 27 kDa protein from Zingiber officinale
Leah Pandiscia, PhD
October 11, 2018
Lytic polysaccharide monooxygenases (LPMOs) have recently been shown to significantly enhance the degradation of recalcitrant polysaccharides and are of interest… Continue reading Quantification of the catalytic performance of C1-cellulose-specific lytic polysaccharide monooxygenases
Leah Pandiscia, PhD
October 11, 2018
Diabetes mellitus comprises a multiple metabolic disorder that affects millions of people worldwide and consequentially poses challenges for clinical treatment. Among the… Continue reading Effects of structurally stabilized EGF and bFGF on wound healing in type I and type II diabetic mice
Leah Pandiscia, PhD
October 11, 2018
A helically distorted and polycondensed bisphenol [1,1′-bibenzo[c]phenanthrene]-2,2′-diol (HEBPOL) and its separated optically pure enantiomers were used to prepare thin films… Continue reading Thin films of an axially chiral bibenzo[c]phenanthrene diol and its enantiomers: Film structure, optical property, and photoelectrochemical response
Leah Pandiscia, PhD
October 11, 2018