Found 9617 Results / Page 239 of 481
2018 / Scientific Reports
mPEG-PLA and PLA-PEG-PLA copolymeric nanoparticles with three different PLA to PEG ratios are synthesized and used for encapsulation of recombinant… Continue reading mPEG-PLA and PLA-PEG-PLA nanoparticles as new carriers for delivery of recombinant human Growth Hormone (rhGH)
2018 / Science Advances
Amyloid-β (Aβ) aggregation and neuroinflammation are consistent features in Alzheimer’s disease (AD) and strong candidates for the initiation of neurodegeneration.… Continue reading The neuronal S100B protein is a calcium-tuned suppressor of amyloid-β aggregation
2000 / Biochemistry
The equilibrium and kinetics of the unfolding and refolding of authentic and recombinant human α-lactalbumin, the latter of which had… Continue reading Equilibrium and Kinetic Studies on Folding of the Authentic and Recombinant Forms of Human R-Lactalbumin by Circular Dichroism Spectroscopy
2005 / The Protein Journal
The activity and conformational change of human placental cystatin (HPC), a low molecular weight thiol proteinase inhibitor (12,500) has been… Continue reading Comparison of Guanidine Hydrochloride (GdnHCl) and Urea Denaturation on Inactivation and Unfolding of Human Placental Cystatin (HPC)
2000 / Protein: Structure, Function, Bioinformatics
The unfolding of human serum albumin (HSA), a multidomain protein, by urea was followed by far‐UV circular dichroism (CD), intrinsic… Continue reading Anion-Induced Stabilization of Human Serum Albumin Prevents the Formation of Intermediate During Urea Denaturation
2018 / Chemical Communications
We report the visible-light circular dichroism (CD) of colourless organic compounds based on interfacial charge-transfer (ICT) transitions with TiO2 nanoparticles. We… Continue reading Visible-light circular dichroism of colourless chiral organic compounds enabled by interfacial charge-transfer transitions
2018 / Journal of Biological Chemistry
Small ubiquitin-like modifier (SUMO) is commonly used as a protein fusion domain to facilitate expression and purification of recombinant proteins,… Continue reading Discovery and engineering of enhanced SUMO protease enzymes
2018 / Scientific Reports
Cold atmospheric plasma (CAP) has great potential for sterilization in the food industry, by deactivation of thermophilic bacteria, but the… Continue reading CAP modifies the structure of a model protein from thermophilic bacteria: mechanisms of CAP-mediated inactivation
2018 / Polymer Chemistry
Stimuli-responsive polypeptides have practical applications in devices and therapeutic delivery. Here we report that coordination to Cd2+ metal species can be… Continue reading Cd2+ coordination: an efficient structuring switch for polypeptide polymers
2018 / The Journal of Organic Chemistry
Hemoproteins have recently emerged as promising biocatalysts for promoting a variety of carbene transfer reactions including cyclopropanation and Y—H insertion… Continue reading Chemoselective Cyclopropanation over Carbene Y-H insertion Catalyzed by an Engineered Carbene Transferase
2018 / FEBS Open Bio
Nascent polypeptide chains fold co‐translationally but the atomic‐level details of this process remain unknown. Here we report crystallographic, de novo modeling and… Continue reading Co‐translational folding of α‐helical proteins: structural studies of intermediate‐length variants of the λ repressor
2018 / ACS Chemical Neuroscience
α-Synuclein (α-Syn) aggregation and amyloid formation are associated with loss of dopaminergic neurons in Parkinson’s disease (PD). In addition, familial… Continue reading Parkinson’s disease associated α-synuclein familial mutants promote dopaminergic neuronal death in Drosophila melanogaster
2018 / Scientific Reports
Today, Gold Nanorods have promised variety of applications in conjugation with biomolecules of interest. Discovery of functional amyloids has also… Continue reading Assembly of Gold Nanorods on HSA Amyloid Fibrils to Develop a Conductive Nanoscaffold for Potential Biomedical and Biosensing Applications
2018 / PLoS ONE
Chlamydia trachomatis (Ct) is the most common sexually transmitted bacterial pathogen, and the leading cause of infectious blindness worldwide. We have… Continue reading The Chlamydia trachomatis PmpD adhesin forms higher order structures through disulphide-mediated covalent interactions
2018 / PLoS ONE
Massive expansion of a DNA hexanucleotide sequence repeat (C2G4) within the human C9orf72 gene has been linked to a number of neurodegenerative… Continue reading (C2G4)n repeat expansion sequences from the C9orf72 gene form an unusual DNA higher-order structure in the pH range of 5-6
2018 / Journal of Molecular Recognition
The present work is a brief overview of the effect of psychostimulant drug mephedrone hydrochloride (4MMC) on a transport protein,… Continue reading Esterase activity and conformational changes of bovine serum albumin toward interaction with mephedrone: Spectroscopic and computational studies
2018 / Inorganic Chemistry Frontiers
For the purpose towards engineering the magnetic anisotropy, chiral binaphthyl substituents with slight electron-withdrawing ability and dibutylamino substituents with intense… Continue reading Heteroleptic Chiral Bis(phthalocyaninato) Terbium Double-Decker Single-Ion Magnets
2018 / Luminescence
The binding affinity between bovine serum albumin (BSA) and copper ferrite (CuFe2O4) nanoparticles in terms of conformation, stability and activity… Continue reading Insights into the binding interaction between copper ferrite nanoparticles and bovine serum albumin: An effect on protein conformation and activity
2018 / JACS
The fabrication of supramolecular chiral nanostructures from achiral materials without the need of pre-existing chirality is a major chal-lenge associated… Continue reading Controllable supramolecular chiral twisted nanoribbons from achiral conjugated oligoaniline derivatives
2018 / Journal of Agricultural and Food Chemistry
Emergence of endogenous nanoparticles in thermally processed food has aroused much attention due to their unique properties and potential biological… Continue reading Characterization of endogenous nanoparticles from roasted chicken breasts
