Found 9617 Results / Page 241 of 481
2018 / Scientific Reports
Cationic antimicrobial peptides (CAMPs) are a promising alternative to treat multidrug-resistant bacteria, which have developed resistance to all the commonly… Continue reading Exploring the role of unnatural amino acids in antimicrobial peptides
2018 / Scientific Reports
NCAM1 and NCAM2 have ectodomains consisting of 5 Ig domains followed by 2 membrane-proximal FnIII domains. In this study we… Continue reading NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor
2018 / Biochemical Journal
The complex formation between the proteins Apoptosis Inducing Factor (AIF) and Cyclophilin A (CypA) following oxidative stress in neuronal cells… Continue reading Binding mode of AIF(370-394) peptide to CypA: insights from NMR, label-free and molecular docking studies
2018 / Nanoscale
The development of safe and effective nano-drug delivery systems to deliver anticancer drugs to targeted cells and organs is crucial… Continue reading Tumor-targeted and nitric oxide-generated nanogels of keratin and hyaluronan for enhanced cancer therapy
2018 / Biomacromolecules
Many studies of drug delivery nano-platforms have explored drug loading affinity or controlled release. The nano-platforms can be influenced by… Continue reading Multilayered controlled drug release silk fibroin nano-film by manipulating secondary structure
2018 / Journal of Peptide Science
Bioactive peptides derived from the receptor‐binding region of human apolipoprotein E have previously been reported. All these peptides, encompassing fragments… Continue reading Human apolipoprotein E as a reservoir of cryptic bioactive peptides: The case of ApoE 133‐167
2018 / Journal of Biological Chemistry
The development of fast-acting and highly stable insulin analogues is challenging. Insulin undergoes structural transitions essential for binding and activation… Continue reading Probing the correlation between insulin activity and structural stability through introduction of the rigid A6–A11 bond
2018 / Nature Communications
The animal-pathogenic oomycete Saprolegnia parasitica causes serious losses in aquaculture by infecting and killing freshwater fish. Like plant-pathogenic oomycetes, S. parasitica employs similar infection… Continue reading Cell entry of a host-targeting protein of oomycetes requires gp96
2018 / International Journal of Biological Macromolecules
Recently, mixed duplex/quadruplex oligonucleotides have attracted great interest for use as biomedical aptamers. In the case of anti-thrombin aptamers, the… Continue reading Duplex/quadruplex oligonucleotides: Role of the duplex domain in the stabilization of a new generation of highly effective anti-thrombin aptamers
2017 / Acta Biomaterialia
Gene transfer using lentiviral vectors has therapeutic applications spanning from monogenic and infectious diseases to cancer. Such gene therapy has to be improved… Continue reading Vectofusin-1, a potent peptidic enhancer of viral gene transfer forms pH-dependent α-helical nanofibrils, concentrating viral particles
2017 / Journal of Chromatography B
Brome mosaic virus (BMV) has been successfully loaded with different types of nanoparticles. However, studies concerning its application as a… Continue reading Biophysical analysis of BMV virions purified using a novel method
2018 / International Journal of Biological Macromolecules
Heat shock proteins (HSPs) are known to confer protection to the stressed cells by rescuing vital host cell proteins. In the… Continue reading Heterologous expression of an engineered protein domain acts as chaperone and enhances thermotolerance of Escherichia coli
2017 / Talanta
We describe the preparation and validation of a novel lateral flow immunoassay test for the detection of human heart fatty… Continue reading A quantum dot-based lateral flow immunoassay for the sensitive detection of human heart fatty acid binding protein (hFABP) in human serum
2018 / International Journal of Biological Macromolecules
Cell division is compromised in DnaAcos mutant E. coli cells due to chromosome over-replication. In these cells, CedA acts as a regulatory… Continue reading Interplay between CedA, rpoB and double stranded DNA: A step towards understanding CedA mediated cell division in E. coli
2017 / Food Hydrocolloids
For greater utilization of meat as a source of high-quality protein supplements, we investigated the effects of heating (30–80 °C) on… Continue reading Rheological behavior, conformational changes and interactions of water-soluble myofibrillar protein during heating
2018 / Chemosphere
Chiral herbicides consist of two or more enantiomers, which usually differ in their biological properties and behave enantioselectively in biochemical… Continue reading Enantiomeric characterization of herbicide lactofen: Enantioseparation, absolute configuration assignment and enantioselective activity and toxicity
2018 / Biochimica et Biophysica Acta (BBA) - General Subjects
β-hydroxyacyl-acyl carrier protein dehydratase (FabZ) is an essential component of type II fatty acid biosynthesis (FAS II) pathway in bacteria.… Continue reading Characterization of isoflavonoids as inhibitors of β-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Moraxella catarrhalis: Kinetics, spectroscopic, thermodynamics and in silico studies
2018 / Chemistry A European Journal
We describe the role of amide groups formed by achiral and chiral moieties to study supramolecular helicity at the molecular… Continue reading Helicity Control of Triphenylamine‐based Supramolecular Polymers: Correlation between Solvent Properties and Helicity in Supramolecular Gels
2018 / Biochemistry
The human synuclein (syn) family is comprised of α-, β-, and γ-syn proteins. α-syn has the highest propensity for aggregation,… Continue reading Comparative Analysis of the Conformation, Aggregation, Interaction, and Fibril Morphologies of Human α-, β-, and γ-Synuclein Proteins
2018 / ACS Sustainable Chemistry & Engineering
Outfitted with numerous coordination and hydrogen bonding sites, nucleotides represent a class of naturally occurring ligands for coordination with metals… Continue reading Multifunctional Inosine Monophosphate Coordinated Metal–Organic Hydrogel: Multistimuli Responsiveness, Self-Healing Properties, and Separation of Water from Organic Solvents
