Found 9617 Results / Page 281 of 481
2018 / Scientific Reports
Peptides are experiencing a new era in medical research, finding applications ranging from therapeutics to vaccines. In spite of the… Continue reading Immunosilencing peptides by stereochemical inversion and sequence reversal: retro-D-peptides
2018 / Polymers for Advanced Technologies
A novel silver nanoparticle doped diblock copolymer was synthesized by a 3‐step process via bulk polymerization process under nitrogen atmosphere.… Continue reading Low temperature splinting activity and catalytic behavior of nano Ag doped sulphamicacid bridged diblock copolymer
2018 / Journal of Natural Products
The in vitro antidiabetic and antihyperlipidemic activities of an alcoholic extract of Trigonella stellata were evaluated in terms of the activation of… Continue reading Bioactivity-Guided Isolation of Potential Antidiabetic and Antihyperlipidemic Compounds from Trigonella stellata
2018 / European Journal of Organic Chemistry
Two enantiomerically pure chiral molybdenum(VI) dioxido complexes (1 and 2) of the type [MoO2L] (L= dianionic, tetradentate ONNO‐ligand) were synthesized… Continue reading Diastereoselective synthesis and catalytic activity of two chiral cis‐dioxido molybdenum(VI) complexes
2018 / European Journal of Organic Chemistry
A nonameric (pyridine−acetylene−phenol−acetylene)4 −pyridine oligomer formed a helical structure by intermolecular templation with hexose such as D‐glucose associated by the… Continue reading Metathesis‐Based Stapling of a Pyridine−Acetylene−Phenol Oligomers Having Alkenyl Side Chains after Intermolecular Templation by Native Saccharides
2018 / Physical Chemistry Chemical Physics
The electronic structures of three previously synthesized Ni-coordinated chlorins with β-substituents of thioketone, fluorene, and ketone were investigated using magnetic… Continue reading Exploring function activated chlorins using MCD spectroscopy and DFT methods: design of a chlorin with a remarkably intense, red Q band
2018 / Molecules
G-quadruplex (G4) is a DNA/RNA conformation that consists of two or more G-tetrads resulting from four-guanine bases connected by Hoogsteen-type… Continue reading CpG Methylation Changes G-Quadruplex Structures Derived from Gene Promoters and Interaction with VEGF and SP1
2018 / Nucleic Acids Research
Thrombin-binding aptamer (TBA) is a DNA 15-mer of sequence 5′-GGT TGG TGT GGT TGG-3′ that folds into a G-quadruplex structure… Continue reading Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity
2018 / Scientific Reports
Collagen hydrogel is a popular extracellular matrix (ECM) material in regenerative medicine and has an isotropic structure. In contrast, native… Continue reading Native collagen hydrogel nanofibres with anisotropic structure using core-shell electrospinning
2018 / Protein Science
Lipopolysaccharide (LPS) is an essential element of nearly all Gram‐negative bacterial outer membranes and serves to protect the cell from… Continue reading Disruption of the E. coli LptC dimerization interface and characterization of lipopolysaccharide and LptA binding to monomeric LptC
2018 / Biomolecules
Antimicrobial peptides (AMPs) constitute a promising alternative for the development of new antibiotics that could potentially counteract the growing number… Continue reading Improving the Activity of Trp-Rich Antimicrobial Peptides by Arg/Lys Substitutions and Changing the Length of Cationic Residues
2018 / ChemMedChem
Five new Au(III)‐peptidodithiocarbamato complexes of the type [AuIIIBr2(dtc‐AA1‐AA2‐OR] (AA1=Sar, L/D‐Pro; AA2=L/D‐Ala, Aib; R=OtBu, TEG), differing in the amino acidic sequence… Continue reading Anticancer gold(III) peptidomimetics: from synthesis to in vitro and ex vivo biological evaluation
2018 / Journal of Peptide Science
Human cystatin C (hCC) is a low molecular mass protein that belongs to the cystatin superfamily. It is an inhibitor… Continue reading Synthesis and physicochemical studies of amyloidogenic hexapeptides derived from human cystatin C
2018 / Journal of Materials Chemistry C
DNA-based functional materials are of great interest for electrical and optical device applications. In this paper, novel DNA-based photo-functional materials… Continue reading Enhanced red emissions of europium(III) chelates in DNA-CTMA complexes
2018 / Bioconjugate Chemistry
Mitochondria-specific delivery methods offer a valuable tool for studying mitochondria-related diseases and provide breakthroughs in therapeutic development. Although several small-molecule… Continue reading Mitochondria-Targeting Peptoids
2018 / Inorganics
Molecular orientation of dyes must be one of the important factors for designing dye-sensitized solar cells (DSSC). As model systems,… Continue reading Computational Treatments of Hybrid Dye Materials of Azobenzene and Chiral Schiff Base Metal Complexes
2018 / ACS Sustainable Chemistry & Engineering
We report on the synthesis and characterization of a novel hybrid nanoflower of manganese and l-arabinose isomerase and its application in… Continue reading Self-Assembled Hybrid Nanoflowers of Manganese Phosphate and l-Arabinose Isomerase: A Stable and Recyclable Nanobiocatalyst for Equilibrium Level Conversion of d-Galactose to d-Tagatose
2018 / Dalton Transactions
Two pure enantiomers of polyoxovanadate clusters [(L-/D-C4O6H2)2V4O8]·2C6N2H18(abbreviated as 1-L and 1-D) have been synthesized by a two-step method. During the two-step synthesis process,… Continue reading A pair of new chiral polyoxovanadates with decent NLO properties
2018 / The Journal of Physical Chemistry B
Cyclic peptides are a promising class of molecules for unique applications. Unfortunately, cyclic peptide design is severely limited by the… Continue reading Designing Well-Structured Cyclic Pentapeptides Based on Sequence–Structure Relationships
2018 / Chemical Research in Toxicology
Perfluorooctanoic acid (PFOA), a persistent organic pollutant known to cause adverse health effects, strongly binds to human serum albumin (HSA).… Continue reading β-Cyclodextrin Reverses Binding of Perfluorooctanoic Acid to Human Serum Albumin
