Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
Dihydroxyacid dehydratase (DHAD) is the third enzyme required for branched-chain amino acid biosynthesis in bacteria, fungi, and plants. DHAD enzymes… Continue reading Function and maturation of the Fe–S center in dihydroxyacid dehydratase from Arabidopsis
Leah Pandiscia, PhD
May 22, 2018
Regulatory agencies recommend a stepwise approach for demonstrating biosimilarity between a proposed biosimilar and reference biological product emphasizing for functional… Continue reading Analytical characterization of recombinant hCG and comparative studies with reference product
Leah Pandiscia, PhD
May 22, 2018
Two racemic tetrathiafulvalene-[2.2]paracyclophane electron donors EDT-TTF-[2.2]paracyclophane 1 and (COOMe)2-TTF-[2.2]paracyclophane 2 have been synthesized via the phosphite mediated cross coupling strategy. Chiral HPLC allowed the… Continue reading Tetrathiafulvalene-[2.2]paracyclophanes: Synthesis, crystal structures, and chiroptical properties
Leah Pandiscia, PhD
May 22, 2018
G-quadruplex has attracted considerable attention due to their prevalent distribution in functional genomic regions and transcripts, which can importantly influence… Continue reading Ethyl-substitutive Thioflavin T as a highly-specific fluorescence probe for detecting G-quadruplex structure
Leah Pandiscia, PhD
May 22, 2018
Vegetable proteins are increasingly used to stabilize oil-in-water (O/W) emulsions. However, emulsions are thermodynamically unstable. Recently, high-intensity ultrasound (US) has… Continue reading Ultrasound improving the physical stability of oil-in-water emulsions stabilized by almond proteins
Leah Pandiscia, PhD
May 22, 2018
Curli are functional amyloids that form a major part of the biofilm produced by many enterobacteriaceae. A multiprotein system around… Continue reading Structural and functional characterization of the Curli adaptor protein CsgF
Leah Pandiscia, PhD
May 22, 2018
Magnetic nanogels (MNGs) are designed to have all the required features for their use as highly efficient trapping materials in… Continue reading Optimizing Circulating Tumor Cells’ Capture Efficiency of Magnetic Nanogels by Transferrin Decoration
Leah Pandiscia, PhD
May 22, 2018
While supramolecular gels have been attracting great interest due to their easy design and fabrication, development of new applications based… Continue reading Photoirradiation-generated radicals in two-component supramolecular gel for polymerization
Leah Pandiscia, PhD
May 22, 2018
G-quadruplex DNA structures are prevalent in genomes and are considered to play important roles in many important biological processes, which… Continue reading Synthesis of quinolinium-based probes and studies of their effects for selective G-quadruplex DNA targeting
Leah Pandiscia, PhD
May 22, 2018
Nanofibers with the cationic fluorescent molecules, 1-pyrenemethylamine hydrochloride (PyrMA) and α,β,γ,δ-tetrakis(1-methylpyridinium-4-yl)porphyrin p-toluenesulfonate (TMPyP), in the presence of complementary anionic chiral polysaccharide,… Continue reading Amplified polarization properties of electrospun nanofibers containing fluorescent dyes and helical polymer
Leah Pandiscia, PhD
May 22, 2018
The interaction between the Pra1 zincophore and the Zrt1 zinc(II) transporter is crucial for adequate Zn(II) acquisition in Candida albicans, the… Continue reading Candida albicans zincophore and zinc transporter interactions with Zn(II) and Ni(II)
Leah Pandiscia, PhD
May 22, 2018
The cellular prion protein (PrPC) is a copper binding protein that undergoes post-translational modifications, such as endoproteolytic alpha cleavage, which… Continue reading Neuroprotective alpha-cleavage of the human prion protein significantly impacts Cu(II) coordination at its His111 site
Leah Pandiscia, PhD
May 22, 2018
Leah Pandiscia, PhD
May 22, 2018
A type of aromatic helical capsules was synthesized. The crystal structure proved an inner cavity that could perform switchable encapsulation… Continue reading A Switchable Helical Capsule for Encapsulation and Release of Potassium Ion
Leah Pandiscia, PhD
May 22, 2018
Magnetic biomaterials are a key focus in medical research. Tropoelastin is the soluble precursor of elastin and is a critical… Continue reading Engineering magnetically responsive tropoelastin spongy-like hydrogels for soft tissue regeneration
Leah Pandiscia, PhD
May 22, 2018
A hydrogen-bonded macrocycle, cyclo[6]aramide, was found to form a supramolecular complex with cytochrome c, which enables the solubilization of the heme… Continue reading The cytochrome c–cyclo[6]aramide complex as a supramolecular catalyst in methanol
Leah Pandiscia, PhD
May 22, 2018
Ostreococcus tauri, the smallest free-living (non-symbiotic) eukaryote yet described, is a unicellular green alga of the Prasinophyceae family. It has… Continue reading Identification and analysis of OsttaDSP, a phosphoglucan phosphatase from Ostreococcus tauri
Leah Pandiscia, PhD
May 22, 2018
Plastics, including poly(ethylene terephthalate) (PET), possess many desirable characteristics and thus are widely used in daily life. However, non-biodegradability, once… Continue reading Structural insight into molecular mechanism of poly(ethylene terephthalate) degradation
Leah Pandiscia, PhD
May 22, 2018
