Found 9617 Results / Page 303 of 481
2017 / Small
The self-assembly of amyloidogenic peptides into β-sheet-rich aggregates is a general feature of many neurodegenerative diseases, including Alzheimer’s disease, which… Continue reading Carbon Nanodot-Sensitized Modulation of Alzheimer’s β-Amyloid Self-Assembly, Disassembly, and Toxicity
2017 / Biochemistry
PEGylated proteins play an increasingly important role in pharmaceutical drug delivery. We recently showed that short poly(ethylene glycol) (PEG) chains… Continue reading The Surface of Protein λ6–85 Can Act as a Template for Recurring Poly(ethylene glycol) Structure
2017 / Advanced Materials
The interplay between noncollagenous proteins and biomineralization is widely accepted, yet the contribution of their secondary structure in mineral formation… Continue reading Disordered Conformation with Low Pii Helix in Phosphoproteins Orchestrates Biomimetic Apatite Formation
2017 / Metallomics
The cellular copper level is strictly regulated since excessive copper is harmful to cells. It has been proposed that the… Continue reading Copper-finger protein of Sp1: the molecular basis of copper sensing
2017 / Polymer Chemistry
The first circularly polarized luminescence (CPL) excitation (CPLE) measurements of poly(fluorene-alt-bithiophene) (PF8T2) aggregates with bisignate CPL/circular dichroism (CD) signals and,… Continue reading The origin of bisignate circularly polarized luminescence (CPL) spectra from chiral polymer aggregates and molecular camphor: anti-Kasha’s rule revealed by CPL excitation (CPLE) spectra
2017 / Biomaterials Science
Peptides that mimic the bioactivity of growth factors are rapidly emerging as therapeutics for a variety of drug delivery applications… Continue reading Design and characterization of hydrogel nanoparticles with tunable network characteristics for sustained release of a VEGF-mimetic peptide
2017 / The Journal of Physical Chemistry B
Peptide self-assembly has a profound biological significance since self-assembled bioactive peptides are gifted with improved bioactivity as well as life-span.… Continue reading High-Resolution Insights into the Stepwise Self-Assembly of Nanofiber from Bioactive Peptides
2017 / Journal of Biological Chemistry
Calmodulin-like (CML) proteins are major EF hand-containing, calcium (Ca2+)-binding proteins with crucial roles in plant development and in coordinating plant… Continue reading Arabidopsis calmodulin-like protein CML36 is a calcium (Ca2+) sensor that interacts with the plasma membrane Ca2+-ATPase Isoform ACA8 and stimulates its activity
2017 / PNAS
Intrinsically disordered proteins (IDPs) are ubiquitous in eukaryotes, and they are often associated with diseases in humans. The protein NUPR1… Continue reading Intrinsically disordered chromatin protein NUPR1 binds to the C-terminal region of Polycomb RING1B
2017 / Journal of Nanoparticle Research
Protein-conjugated CdS nanocrystals (NCs) with different morphology have been synthesized under biomimetic condition using trypsin as capping agent in aqueous… Continue reading Shape-controlled synthesis of protein-conjugated CdS nanocrystals (NCs) and study on the binding of Cd2+/CdS to trypsin
2017 / ACS Nano
Self-replication at the molecular level is often seen as essential to the early origins of life. Recently a mechanism of… Continue reading Structural and Spectroscopic Properties of Assemblies of Self-Replicating Peptide Macrocycles
2017 / New Journal of Chemistry
Binding interactions between human serum albumin (HSA) and tobramycin (TOB) under simulated physiological conditions (pH = 7.4) were explored using… Continue reading Molecular mechanism of tobramycin with human serum albumin for probing binding interactions: multi-spectroscopic and computational approaches
2017 / Metallomics
The fission yeast Schizosaccharomyces pombe expresses the CCAAT-binding factor Php4 in response to iron deprivation. Php4 forms a transcription complex with Php2,… Continue reading Schizosaccharomyces pombe Grx4 regulates the transcriptional repressor Php4 via [2Fe–2S] cluster binding
2017 / Macromolecules
Herein, we present a novel synthetic strategy, to amino-acid-free peptide synthesis based on postpolymerization conversion, for chiral nonnatural polypeptides. Optically… Continue reading Synthesis of Nonnatural Helical Polypeptide via Asymmetric Polymerization and Reductive Cleavage of N–O Bond
2017 / Biochemistry
The catalytic active site of Mn-specific superoxide dismutase (MnSOD) is organized around a redox-active Mn ion. The most highly conserved… Continue reading A Single Outer-Sphere Mutation Stabilizes apo-Mn Superoxide Dismutase by 35 °C and Disfavors Mn Binding
2017 / Medicinal Chemistry Research
The comparative phytochemical constituents of three Limonium species Limonium myrianthum, Limonium leptophyllum, and Limonium gmelinii afforded a new compound (2R,3S)-2,3,4-trihydroxy-2-methylbutyl gallate (1) and twenty known compounds… Continue reading Phytochemical characterization and biological activity of secondary metabolites from three Limonium species
2017 / Phytochemistry Letters
Extensive screening for the antiproliferative activity of different compounds found in trees was performed by extracting the leaves of Aphananthe aspera (Thunb.)… Continue reading Antiproliferative constituents from Aphananthe asperaleaves
2017 / Catalysts
Through genetic engineering technology, catalase (CAT) and superoxide dismutase (SOD) have been separately fused to an elastin-like polypeptide (ELP). Thus,… Continue reading Co-Immobilization of Superoxide Dismutase with Catalase on Soft Microparticles Formed by Self-Assembly of Amphiphilic Poly(Aspartic Acid)
2017 / Nanoscale
Mercury sulfide (HgS) nanoparticles (NPs) were prepared in the presence of water-soluble thiols as capping ligands in aqueous solutions. Chiral… Continue reading The effect of surface ligands on the optical activity of mercury sulfide nanoparticles
2017 / Biotechnology Progress
During purification process development of a recombinant therapeutic protein, an endoproteolytic activity endogenous to the Chinese hamster ovary (CHO) cells… Continue reading Characterization of a cathepsin D protease from CHO cell-free medium and mitigation of its impact on the stability of a recombinant therapeutic protein
