Found 9617 Results / Page 312 of 481
2017 / JACS
To understand the role of ribose G-quartets and how they affect the properties of G-quadruplex structures, we studied three systems… Continue reading Unexpected Position-dependent Effects of Ribose G-quartets in G-quadruplexes
2017 / Phytochemistry Letters
An investigation on the chemical constituents in the root barks of Litsea glutinosa was performed for the first time. Three new lignan… Continue reading New lignan glycosides from the root barks of Litsea glutinosa
2017 / ACS Nano
We report the development of a quantum dot (QD)-peptide-fullerene (C60) electron transfer (ET)-based nanobioconjugate for the visualization of membrane potential… Continue reading Quantum Dot-Peptide-Fullerene Bioconjugates for Visualization of In Vitro and In Vivo Cellular Membrane Potential
2017 / ACS Synthetic Biology
Alternative scaffolds for biomolecular recognition are being developed to overcome some of the limitations associated with immunoglobulin domains. The repeat-in-toxin… Continue reading Catch and Release: Engineered Allosterically-Regulated β-roll Peptides Enable On/Off Biomolecular Recognition
2017 / Metallomics
Uranium is the heaviest natural element, mainly found in aqueous medium as the hexavalent uranyl ion (UO22+). Bones are the… Continue reading Reactivity of U-associated osteopontin with lactoferrin: a one-to-many complex
2017 / International Journal of Molecular Sciences
The major house dust mite allergen, Der p 1, is a papain-like cysteine protease expressed as an inactive precursor, proDer… Continue reading The Lys-Asp-Tyr Triad within the Mite Allergen Der p 1 Propeptide Is a Critical Structural Element for the pH-Dependent Initiation of the Protease Maturation
2017 / International Journal of Biological Macromolecules
β/γ-Crystallins, the predominant structural proteins in vertebrate lens with lifelong stability to maintain lens transparency, share a high similarity in… Continue reading Effects of cataract-causing mutations W59C and W151C on βB2-crystallin structure, stability and folding
2017 / Talanta
Amyloid fibrillation is a nucleation-dependent process known be involved in the development of more than 20 progressive and chronic diseases.… Continue reading Probing Amylin Fibrillation at an Early Stage via a Tetracysteine-Recognising Fluorophore
2017 / Analyst
Aptamer-based biosensing, which uses short, single-stranded nucleic acid segments to bind to a target, can be advantageous over antibody-based diagnostics… Continue reading Enhancing the Sensing Specificity of a MoS2 Nanosheet-Based FRET Aptasensor Using a Surface Blocking Strategy
2017 / International Journal of Biological Macromolecules
In this study, we have analyzed the structural and functional changes in the nature of Allium sativum Protease Inhibitor (ASPI) on undergoing… Continue reading Biophysical insight into structure-function relation of Allium sativum Protease Inhibitor by thermal, chemical and pH-induced modulation using comprehensive spectroscopic analysis
2017 / International Journal of Biological Macromolecules
Poly-γ-glutamic acid (PGA) was modified with phosphorylating agents such as sodium metaphosphate and potassium metaphosphate in the culture medium of Bacillus… Continue reading Feasible protein aggregation of phosphorylated poly-γ-glutamic acid derivative from Bacillus subtilis (natto)
2017 / ACS Sustainable Chemistry & Engineering
In this paper, we report the studies relevant to controlling the size of protein protected gold nanoclusters (AuNCs). In order… Continue reading Green synthesis of protein protected fluorescent gold nanoclusters (AuNCs): Reducing the size of the AuNCs by partially occupying the Ca2+ site by La3+ in apo-α-lactalbumin and the utility of AuNCs in sensing Hg2+
2017 / Phytochemistry Letters
Plants have developed defensive specialized metabolites over the course of evolution. In the genus Hordeum, which includes the important cereal crop… Continue reading Evolutionary changes in defensive specialized metabolism in the genus Hordeum
2017 / Alzheimer's & Dementia
Tau-mediated toxicity in Alzheimer’s disease is thought to operate through low-n oligomers, rather than filamentous aggregates. However, the nature of oligomers and pathways… Continue reading Extracellular low-n oligomers of tau cause selective synaptotoxicity without affecting cell viability
2017 / Fitoterapia
Seven new compounds including four lanostane triterpenoids, lucidenic acids Q-S (1–3) and methyl ganoderate P (4), and three triterpene-farnesyl hydroquinone… Continue reading Triterpenes and meroterpenes from Ganoderma lucidum with inhibitory activity against HMGs reductase, aldose reductase and α-glucosidase
2017 / International Immunopharmacology
Allergen-specific sublingual immunotherapy (SLIT) is well known as an effective and non-invasive route to induce allergy desensitization. The goal of… Continue reading Enhanced sublingual immunotherapy by TAT-fused recombinant allergen in a murine rhinitis model
2017 / Carbohydrate Research
In the synthesis of the main yellow pigment hydroxysafflor yellow A (HSYA), that is present in safflower petals, the key… Continue reading Oxidation of 3,5-di-C-(per-O-acetylglucopyranosyl)phloroacetophenone in the synthesis of hydroxysafflor yellow A
2017 / Journal of Pharmaceutical and Biomedical Analysis
Calicheamicin, γ1I, is a remarkable DNA binding-cleaving, enediyne-containing, natural product that exhibits potent antitumor activity. In this study, we used… Continue reading Circular Dichroism Analysis of the Calicheamicin-DNA Interaction Revisited
2017 / Electrochimica Acta
This manuscript describes the result of a series of electrochemical, spectroscopic and thermodynamic studies into oligonucleotide hairpin structures equipped with… Continue reading A study of the interactions of Hg(II) with T-T mispair containing hairpin loops
2017 / International Journal of Biological Macromolecules
Seeds of tropical legumes posses a repertoire of proteinase inhibitors (PI) and the current study highlights some structural/functional features of… Continue reading Caesalpinia bonduc serine proteinase inhibitor CbTI–2: Exploring the conformational features and antimalarial activity
