KnowledgeBase Articles Archive

pH induced single step shift of hydrophobic patches followed by formation of an MG state and an amyloidogenic intermediate in Lima Bean Trypsin Inhibitor (LBTI)

2017 / International Journal of Biological Macromolecules

Lima Bean Trypsin Inhibitor (LBTI) is 83 residues monomeric protein of 9.0 KDa, consisting of six antiparallel β-strands and can… Continue reading pH induced single step shift of hydrophobic patches followed by formation of an MG state and an amyloidogenic intermediate in Lima Bean Trypsin Inhibitor (LBTI)

Interaction rule and mechanism of perfluoroalkyl sulfonates containing different carbon chains with human serum albumin

2017 / RSC Advances

In this study, the toxic mechanism and effects of perfluorooctane sulfonate (PFOS), perfluorohexane sulfonate (PFHS), and perfluorobutane sulfonate (PFBS) were… Continue reading Interaction rule and mechanism of perfluoroalkyl sulfonates containing different carbon chains with human serum albumin

Synthesis and chiroptical properties of helical polyallenes bearing chiral cholesteryl pendant groups

2017 / Journal of Polymer Science Part A: Polymer Chemistry

A cholesteryloxyallene (1) bearing chiral cholesteryl pendant group was designed and synthesized. Living polymerization of this monomer with an allylnickel… Continue reading Synthesis and chiroptical properties of helical polyallenes bearing chiral cholesteryl pendant groups

Porphyrin Bound to i-motifs: Intercalation versus External Groove Binding

2017 / Chemistry An Asian Journal

G-rich and C-rich DNA can fold into the tetrastranded helical structures G-quadruplex or C-quadruplex (i-motif) that are considered as specific… Continue reading Porphyrin Bound to i-motifs: Intercalation versus External Groove Binding

Hydrogen peroxide inhibition of bicupin oxalate oxidase

2017 / PLoS ONE

Oxalate oxidase is a manganese containing enzyme that catalyzes the oxidation of oxalate to carbon dioxide in a reaction that… Continue reading Hydrogen peroxide inhibition of bicupin oxalate oxidase

pH-induced conformational change of natural cyclic lipopeptide surfactin and the effect on protease activity

2017 / Colloids and Surfaces B: Biointerfaces

The cyclic lipopeptide surfactin (SF) is one of the promising environmental friendly biosurfactants abundantly produced by microorganisms such as Bacillus subtilis.… Continue reading pH-induced conformational change of natural cyclic lipopeptide surfactin and the effect on protease activity

Identification and characterization of a neutralizing monoclonal antibody that provides complete protection against Yersinia pestis

2017 / PLoS ONE

Yersinia pestis (Y. pestis) has caused an alarming number of deaths throughout recorded human history, and novel prophylactics and therapeutics are necessary… Continue reading Identification and characterization of a neutralizing monoclonal antibody that provides complete protection against Yersinia pestis

Effect of chemical denaturants on the conformational stability of GyrB subunit of DNA gyrase from Salmonella enterica serovar Typhi

2017 / International Journal of Biological Macromolecules

DNA gyrase, a type II topoisomerase maintains the topology of DNA by introducing negative supercoils using energy generated by ATP… Continue reading Effect of chemical denaturants on the conformational stability of GyrB subunit of DNA gyrase from Salmonella enterica serovar Typhi

Production of a recombinant swollenin from Trichoderma harzianum in Escherichia coli and its potential synergistic role in biomass degradation

2017 / Microbial Cell Factories

Fungal swollenins (SWOs) constitute a class of accessory proteins that are homologous to canonical plant expansins. Expansins and expansin-related proteins… Continue reading Production of a recombinant swollenin from Trichoderma harzianum in Escherichia coli and its potential synergistic role in biomass degradation

The effect of β-sheet breaker peptides on metal associated Amyloid-β peptide aggregation process

2017 / Biophysical Chemistry

Far-UV Circular Dichroism experiments and Atomic Force Microscopy tomography are employed to assess the impact of β-sheet breakers on the… Continue reading The effect of β-sheet breaker peptides on metal associated Amyloid-β peptide aggregation process

Synthesis, characterization and photo-physical properties of Eu(III) complexes and its luminescent thin films

2017 / Optical Materials

Luminescent chiral europium(III) complexes EuLRCl3 (1) and EuLSCl3 (2) were synthesised [where LR and LS are schiff-base ligands of 2,9-dialdehyde 1,10-phenanthroline and (R) and (S) isomer… Continue reading Synthesis, characterization and photo-physical properties of Eu(III) complexes and its luminescent thin films

Inhibition of HSA Fibrillation by Two Dimensional Nanoparticles

2017 / The Journal of Physical Chemistry B

The formation and deposition of amyloid fibrils have been linked to the pathogenesis of numerous debilitating neurodegenerative disorders. Serum albumins… Continue reading Inhibition of HSA Fibrillation by Two Dimensional Nanoparticles

Ultrafast spectroscopy on DNA-cleavage by endonuclease in molecular crowding

2017 / International Journal of Biological Macromolecules

The jam-packed intracellular environments differ the activity of a biological macromolecule from that in laboratory environments (in vitro) through a… Continue reading Ultrafast spectroscopy on DNA-cleavage by endonuclease in molecular crowding

Structure-dependent binding of hnRNP A1 to telomere RNA

2017 / JACS

Telomeric repeat-containing RNA is a new non-coding RNA molecule that performs various bio-functions. Heterogeneous nuclear ribonucleoprotein (hnRNP) A1 is an… Continue reading Structure-dependent binding of hnRNP A1 to telomere RNA

Intrinsic Toxin-Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB

2017 / mBio

Clostridium difficile infection (CDI) is a major cause of hospital-associated, antibiotic-induced diarrhea, which is largely mediated by the production of… Continue reading Intrinsic Toxin-Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB

Fluorinated ionic liquids for protein drug delivery systems: Investigating their impact on the structure and function of lysozyme

2017 / International Journal of Pharmaceutics

Since the approval of recombinant human insulin by FDA in 1982, more than 200 proteins are currently available for pharmaceutical… Continue reading Fluorinated ionic liquids for protein drug delivery systems: Investigating their impact on the structure and function of lysozyme

Au38Cu1(2-PET)24 Nanocluster : Synthesis, Enantioseparation and Luminescence

2017 / Dalton Transactions

A CuAu38 bimetallic nanocluster was synthesized by adding a single copper atom to the Au38(2-PET)24 nanocluster. The absence of CuxAu38(2-PET)24… Continue reading Au38Cu1(2-PET)24 Nanocluster : Synthesis, Enantioseparation and Luminescence

Synthesis and Catalytic Applications of a Triptycene-Based Monophosphine Ligand for Palladium-Mediated Organic Transformations

2017 / ACS Omega

1-Methoxy-8-(diphenylphosphino)triptycene (1), featuring high structural rigidity and steric bulkiness around the phosphine functionality, was synthesized as a new chiral monophosphine… Continue reading Synthesis and Catalytic Applications of a Triptycene-Based Monophosphine Ligand for Palladium-Mediated Organic Transformations

Interaction of Biliverdin Chromophore with Near-Infrared Fluorescent Protein BphP1-FP Engineered from Bacterial Phytochrome

2017 / International Journal of Molecular Sciences

Near-infrared (NIR) fluorescent proteins (FPs) designed from PAS (Per-ARNT-Sim repeats) and GAF (cGMP phosphodiesterase/adenylate cyclase/FhlA transcriptional activator) domains of bacterial… Continue reading Interaction of Biliverdin Chromophore with Near-Infrared Fluorescent Protein BphP1-FP Engineered from Bacterial Phytochrome

Mesomorphism, polymerization, and chirality induction in α-cyanostilbene-functionalized diacetylene-assembled films: Photo-triggered Z/E isomerization

2017 / Journal of Polymer Science Part A: Polymer Chemistry

Engineering of molecular stacking arrangement via environmental stimuli is of particular interest in stimuli-responsive self-assembling architectures. A novel dual photo-functionalized… Continue reading Mesomorphism, polymerization, and chirality induction in α-cyanostilbene-functionalized diacetylene-assembled films: Photo-triggered Z/E isomerization

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pH induced single step shift of hydrophobic patches followed by formation of an MG state and an amyloidogenic intermediate in Lima Bean Trypsin Inhibitor (LBTI)

Interaction rule and mechanism of perfluoroalkyl sulfonates containing different carbon chains with human serum albumin

Synthesis and chiroptical properties of helical polyallenes bearing chiral cholesteryl pendant groups

Porphyrin Bound to i-motifs: Intercalation versus External Groove Binding

Hydrogen peroxide inhibition of bicupin oxalate oxidase

pH-induced conformational change of natural cyclic lipopeptide surfactin and the effect on protease activity

Identification and characterization of a neutralizing monoclonal antibody that provides complete protection against Yersinia pestis

Effect of chemical denaturants on the conformational stability of GyrB subunit of DNA gyrase from Salmonella enterica serovar Typhi

Production of a recombinant swollenin from Trichoderma harzianum in Escherichia coli and its potential synergistic role in biomass degradation

The effect of β-sheet breaker peptides on metal associated Amyloid-β peptide aggregation process

Synthesis, characterization and photo-physical properties of Eu(III) complexes and its luminescent thin films

Inhibition of HSA Fibrillation by Two Dimensional Nanoparticles

Ultrafast spectroscopy on DNA-cleavage by endonuclease in molecular crowding

Structure-dependent binding of hnRNP A1 to telomere RNA

Intrinsic Toxin-Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB

Fluorinated ionic liquids for protein drug delivery systems: Investigating their impact on the structure and function of lysozyme

Au38Cu1(2-PET)24 Nanocluster : Synthesis, Enantioseparation and Luminescence

Synthesis and Catalytic Applications of a Triptycene-Based Monophosphine Ligand for Palladium-Mediated Organic Transformations

Interaction of Biliverdin Chromophore with Near-Infrared Fluorescent Protein BphP1-FP Engineered from Bacterial Phytochrome

Mesomorphism, polymerization, and chirality induction in α-cyanostilbene-functionalized diacetylene-assembled films: Photo-triggered Z/E isomerization

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