Found 9617 Results / Page 314 of 481
2017 / Glycoconjugate Journal
Ajowan (Trachyspermum ammi L.) spice has been used in food preparations and also as a traditional medicine in Ayurveda. Although a… Continue reading Structural and functional characterization of a novel immunomodulatory glycoprotein isolated from ajowan (Trachyspermum ammi L.)
2017 / European Journal of Pharmaceutical Sciences
The evaluation of the structural stability and bioactivity of monoclonal antibodies (mAb) is a crucial step in the development of… Continue reading Biophysical study of bevacizumab structure and bioactivity under thermal and pH-stresses
2017 / Journal of Molecular Structure
Ferulic acid is a major phenolic acid found in numerous plant species in conjugated form. It binds to enzymes and… Continue reading Spectroscopic and thermodynamic studies on ferulic acid – alpha-2-macroglobulin interaction
2017 / Journal of Ethnopharmacology
The evaluation of the antimycobacterial activity of extracts of medicinal plants used by Mayos against tuberculosis and respiratory problems, allowed… Continue reading New Isoflavonoids from the Extract of Rhynchosia precatoria (Humb. & Bonpl. ex Willd.) DC. and their antimycobacterial activity
2017 / Colloids and Surfaces A: Physicochemical and Engineering Aspects
Binding of surfactants to biomacromolecules is an active field of current interest at the interface of chemical biology and medicinal… Continue reading In vitro evaluation of the non-covalent interactions of hemoglobin with distinctively modified gemini surfactants: effect of structural variation
2017 / European Journal of Medicinal Chemistry
KR-12-a5 is a 12-meric α-helical antimicrobial peptide (AMP) with dual antimicrobial and anti-inflammatory activities designed from human cathelicidin LL-37. We… Continue reading LL-37-derived short antimicrobial peptide KR-12-a5 and its d-amino acid substituted analogs with cell selectivity, anti-biofilm activity, synergistic effect with conventional antibiotics, and anti-inflammatory activity
2017 / International Journal of Biological Macromolecules
Inhibition of glycation is an important approach for alleviating diabetic complications. Alliin, the most abundant sulphur compound in garlic has… Continue reading Inhibitory effect of alliin from Allium sativum on the glycation of superoxide dismutase
2017 / Biochemical and Biophysical Research Communications
RAPTA compounds, ([Ru(η6-arene)(PTA)Cl2], PTA = 1,3,5-triaza-7-phosphaadamantane), have been reported to overcome drug resistance in cisplatin resistant cells. However, the exact mechanism of… Continue reading Biochemical and biophysical characterization of ruthenation of BRCA1 RING protein by RAPTA complexes and its E3 ubiquitin ligase activity
2017 / Inorganica Chimica Acta
The synthesis and characterization of a family of LnIIIcomplexes (Ln = Gd(1), Tb(2), Dy(3), Ho(4) and Er (5)) of formula… Continue reading Synthesis, characterization, computational study, and biological relevance of a family of isostructural, mononuclear Ln (Ln = Gd, Tb, Dy, Ho, Er) complexes containing pyridoxine, an essential ingredient of vitamin B6 enzyme
2017 / Journal of Inorganic Biochemistry
Cisplatin (CDDP) can form interprotein cross-links, leading to the formation of platinated oligomers. A dimer, a trimer and higher oligomers… Continue reading A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin
2017 / Archives of Biochemistry and Biophysics
1-Aminocyclopropane-1-carboxylic acid oxidase (ACCO) is a non heme iron(II) containing enzyme that catalyzes the final step of the ethylene biosynthesis… Continue reading Characterization of Cu(II)-reconstituted ACC Oxidase using experimental and theoretical approaches
2017 / Biochemical and Biophysical Research Communications
Amylomaltase catalyzes α-1,4 glucosyl transfer reaction to yield linear or cyclic oligosaccharide products. The aim of this work is to… Continue reading Y418 in 410s loop is required for high transglucosylation activity and large-ring cyclodextrin production of amylomaltase from Corynebacterium glutamicum
2017 / Biochemical Engineering Journal
The molecular interactions between pancreatic lipase (PL) and five triterpenoid saponins compounds, including tea saponin, oleanolic acid, betulin, ginsenoside Ro,… Continue reading The effect of triterpenoid saponins on pancreatic lipase in vitro: Activity, conformation, kinetics, thermodynamics and morphology
2017 / International Journal of Pharmaceutics
Tuberculosis (TB) remains a major global health problem. The use of ethionamide (ETH), a main second line drug, is associated… Continue reading Cyclodextrin-based nanocarriers containing a synergic drug combination: a potential formulation for pulmonary administration of antitubercular drugs
2017 / Vaccine
Human papillomavirus (HPV)-6 and HPV11 are the major etiological causes of condylomata acuminate. HPV neutralization by vaccine-elicited neutralizing antibodies can… Continue reading Bacterially expressed human papillomavirus type 6 and 11 bivalent vaccine: Characterization, antigenicity and immunogenicity
2017 / European Journal of Medicinal Chemistry
Within this manuscript design, synthesis of novel 2-imidazolinyl substituted benzo[b]thieno-2-carboxamides bearing either benzimidazole or benzothiazole subunit and biological activity are… Continue reading Novel amidino substituted benzimidazole and benzothiazole benzo[b]thieno-2-carboxamides exert strong antiproliferative and DNA binding properties
2017 / European Journal of Medicinal Chemistry
A new series of pyrimidine derivatives 5, 9a-d and 12a-d was synthesized by an efficient procedure. The antibacterial activity of the new compounds was… Continue reading Antibacterial activity and mechanism of action of the benzazole acrylonitrile-based compounds: In vitro, spectroscopic, and docking studies
2017 / International Journal of Biological Macromolecules
We report a novel method that exploits the differential solubility properties of native and denatured proteins to distinguish between them.… Continue reading Differential behaviorof native and denatured collagen in the presence of alcoholic solvents: A gateway to instant structural analysis
2017 / Structure
ERdj5, composed of an N-terminal J domain followed by six thioredoxin-like domains, is the largest protein disulfide isomerase family member… Continue reading The Highly Dynamic Nature of ERdj5 Is Key to Efficient Elimination of Aberrant Protein Oligomers through ER-Associated Degradation
2017 / Acta Biomaterialia
The delivery performance of non-viral gene vectors is greatly related to their intracellular kinetics. Cationic helical polypeptides with potent membrane… Continue reading Manipulating the Membrane Penetration Mechanism of Helical Polypeptides via Aromatic Modification for Efficient Gene Delivery
