Found 9617 Results / Page 324 of 481
2014 / PLoS ONE
Cupredoxins are widespread copper-binding proteins, mainly involved in electron transfer pathways. They display a typical rigid greek key motif consisting… Continue reading Spectroscopic Characterization of a Green Copper Site in a Single-Domain Cupredoxin
2011 / PLoS ONE
Virus capsid assembly constitutes an attractive target for the development of antiviral therapies; a few experimental inhibitors of this process… Continue reading Rationally Designed Interfacial Peptides Are Efficient In VitroInhibitors of HIV-1 Capsid Assembly with Antiviral Activity
2010 / PLoS Pathogens
Bacterial growth in multicellular communities, or biofilms, offers many potential advantages over single-cell growth, including resistance to antimicrobial factors. Here… Continue reading Uropathogenic Escherichia coli Modulates Immune Responses and Its Curli Fimbriae Interact with the Antimicrobial Peptide LL-37
2017 / Chinese Chemical Letters
Four structurally unprecedented aconitane-type C19-diterpenoid alkaloid glycosides with isomeric arabinosyls, named aconicarmichosides A–D (1–4), were isolated from an aqueous extract… Continue reading Unprecedented C19-diterpenoid alkaloid glycosides from an aqueous extract of “fu zi”: Neoline 14-O-l-arabinosides with four isomeric l-anabinosyls
2017 / Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
We demonstrate an advance in the fabrication of circular dichroism (CD) sensors for detection of Cd2 + and S2 − based on chiral CdS… Continue reading A circular dichroism sensor for selective detection of Cd2 + and S2 − based on the in-situ generation of chiral CdS quantum dots
2017 / Phytochemistry Letters
Phytochemical investigation of an EtOH extract of Pharbitis nil seeds (Convolvulaceae) resulted in the isolation and identification of a new neolignan, 7R,8S-threo-dihydroxydehydrodiconiferyl… Continue reading Neolignan and monoterpene glycoside from the seeds of Pharbitis nil
2017 / Food Hydrocolloids
The purpose of this study was to produce lysozyme-pullulan conjugates under mild Maillard reaction conditions and investigate the influence of… Continue reading Synthesis and structural characterization of lysozyme–pullulan conjugates obtained by the Maillard reaction
2017 / Biophysical Journal
Pyroglutamate-modified amyloid-β (pEAβ) has been described as a relevant Aβ species in Alzheimer’s-disease-affected brains, with pEAβ (3–42) as a dominant isoform. Aβ (1–40) and… Continue reading Pyroglutamate-Modified Amyloid-β(3–42) Shows α-Helical Intermediates before Amyloid Formation
2017 / Phytochemistry Letters
Two new compounds namely 7,4′-dihydroxy-2′-methoxy-3′-(3-methylbut-2-enyl)isoflavanone (1) and 5,7,3′-trihydroxy-8-(3-methylbut-2-enyl)-[6′′,6′′-dimethylpyrano(2′′,3′′:4′,5′)]isoflavone (4) were isolated from the root bark of Erythrina droogmansiana together with eight known… Continue reading Chemical constituents of the root bark of Erythrina droogmansiana
2017 / Biophysical Journal
The strong and usually denaturing interaction between anionic surfactants (AS) and proteins/enzymes has both benefits and drawbacks: for example, it… Continue reading Refolding of SDS-Unfolded Proteins by Nonionic Surfactants
2017 / Biochimica et Biophysica Acta (BBA) - General Subjects
Host defence peptides (HDPs) are evolutionarily conserved components of innate immunity. Human HDPs, produced by a variety of immune cells… Continue reading A new cryptic host defense peptide identified in human 11-hydroxysteroid dehydrogenase-1 β-like: from in silico identification to experimental evidence
2017 / PLoS ONE
Type 1 diabetes and thyroid disease are T cell-dependent autoimmune endocrinopathies. The standard substitutive administration of the deficient hormones does… Continue reading Use of short interfering RNA delivered by cationic liposomes to enable efficient down-regulation of PTPN22 gene in human T lymphocytes
2017 / Chemosphere
BPF (Bisphenol-F), a member of the bisphenol family, having a wide range of industrial applications is gradually replacing Bisphenol-A. It… Continue reading Binding of Bisphenol-F, a bisphenol analogue, to calf thymus DNA by multi-spectroscopic and molecular docking studies
2017 / Journal of Solid State Chemistry
In this report, L-diphenylalanine-decorated tetraphenylporphyrin (TPPtFFC) was synthesized and self-assembled into regular nano-architechtures. The morphology of the assemblies varied with… Continue reading J-aggregation in porphyrin nanoparticles induced by diphenylalanine
2009 / PLoS Pathogens
Infection, survival, and proliferation of pathogenic bacteria in humans depend on their capacity to impair host responses and acquire nutrients… Continue reading Unique Structure and Stability of HmuY, a Novel Heme-Binding Protein of Porphyromonas gingivalis
2013 / PLoS ONE
Cell-penetrating peptides (CPPs) can traverse cellular membranes and deliver biologically active molecules into cells. In this study, we demonstrate that… Continue reading Endocytic Trafficking of Nanoparticles Delivered by Cell-penetrating Peptides Comprised of Nona-arginine and a Penetration Accelerating Sequence
2013 / PLoS ONE
G protein-coupled receptors (GPCRs) exhibit some level of basal signaling even in the absence of a bound agonist. This basal… Continue reading High-Level Expression, Purification and Characterization of a Constitutively Active Thromboxane A2 Receptor Polymorphic Variant
2014 / PLoS ONE
The epidermal growth factor receptor (EGFR) is a member of the ErbB family of receptor tyrosine kinases. EGFR is activated… Continue reading Modulating the Structure of EGFR with UV Light: New Possibilities in Cancer Therapy
2010 / PLoS ONE
Proteins constituting the presynaptic machinery of vesicle release undergo substantial conformational changes during the process of exocytosis. While changes in… Continue reading CHL1 Is a Selective Organizer of the Presynaptic Machinery Chaperoning the SNARE Complex
2013 / PLoS ONE
The polyunsaturated fatty acid (PUFA) synthases from deep-sea bacteria invariably contain multiple acyl carrier protein (ACP) domains in tandem. This… Continue reading Solution Structure of the Tandem Acyl Carrier Protein Domains from a Polyunsaturated Fatty Acid Synthase Reveals Beads-on-a-String Configuration
