Found 9617 Results / Page 323 of 481
2017 / Journal of Inorganic Biochemistry
Guanine-rich DNA sequences can undergo self-assembly into unique G-quadruplex structures that interfere with the binding of proteins to the same… Continue reading Arylsulfanyl groups – Suitable side chains for 5-substituted 1,10-phenanthroline and nickel complexes as G4 ligands and telomerase inhibitors
2017 / Journal of Inorganic Biochemistry
Five new copper(II) complexes of the type [Cu(Nsingle bondO)(Nsingle bondN)(ClO4)2], in which Nsingle bondO = 4-fluorophenoxyacetic acid hydrazide (4-FH) or 4-nitrobenzoic hydrazide… Continue reading Novel copper(II) complexes with hydrazides and heterocyclic bases: Synthesis, structure and biological studies
2017 / Journal of Pharmaceutical Sciences
From 2002 to 2003, a global pandemic of severe acute respiratory syndrome (SARS) spread to five continents and caused 8,000… Continue reading Optimization of the production process and characterization of the yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1), a SARS vaccine candidate
2017 / Tetrahedron
Two new lignan-iridoid glucoside diesters (2 and 3), together with their putative biosynthetic precursor 10-O-trans-caffeoyl-6α-hydroxyl-dihydromonotropein (1), were characterized from the leaves of Vaccinium… Continue reading Two new lignan-iridoid glucoside diesters from the leaves of Vaccinium bracteatum and their relative and absolute configuration determination by DFT NMR and TDDFT-ECD calculation
2016 / Science Advances
Folded peptides present complex exterior surfaces specified by their amino acid sequences, and the control of these surfaces offers high-precision… Continue reading Computationally designed peptides for self-assembly of nanostructured lattices
2012 / Science Signaling
Kinase suppressor of Ras-1 (KSR-1) is an essential scaffolding protein that coordinates the assembly of the mitogen-activated protein kinase (MAPK)… Continue reading A CC-SAM, for Coiled Coil–Sterile α Motif, Domain Targets the Scaffold KSR-1 to Specific Sites in the Plasma Membrane
2010 / Science Translational Medicine
Vaccines against influenza viruses with pandemic potential, including H5N1, are under development. Because of a lack of preexisting immunity to… Continue reading Vaccines with MF59 Adjuvant Expand the Antibody Repertoire to Target Protective Sites of Pandemic Avian H5N1 Influenza Virus
2002 / Science
Amyloid is associated with debilitating human ailments including Alzheimer’s and prion diseases. Biochemical, biophysical, and imaging analyses revealed that fibers… Continue reading Role of Escherichia coli Curli Operons in Directing Amyloid Fiber Formation
2000 / Science
Prion proteins can serve as genetic elements by adopting distinct physical and functional states that are self-perpetuating and heritable. The… Continue reading Nucleated Conformational Conversion and the Replication of Conformational Information by a Prion Determinant
2017 / Science Advances
Semiconductors with chiral geometries at the nanoscale and mesoscale provide a rich materials platform for polarization optics, photocatalysis, and biomimetics.… Continue reading Assembly of mesoscale helices with near-unity enantiomeric excess and light-matter interactions for chiral semiconductors
2017 / Science
DNA charge transport chemistry offers a means of long-range, rapid redox signaling. We demonstrate that the [4Fe4S] cluster in human… Continue reading The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport
2017 / Advanced Optical Materials
Chiral semiconductor nanomaterials with optical activity have intrigued magnificent attention due to their potential technological applications, but so far there… Continue reading Chiral Nanostructured CuO Films with Multiple Optical Activities
2017 / Fitoterapia
Six novel calyxins, named calyxin T-W, ent-calyxin T and ent-calyxin U were isolated from the seeds of Alpinia katsumadai Hayata.… Continue reading Experimental and theoretical calculation studies on the structure elucidation and absolute configuration of calyxins from Alpinia katsumadai
2017 / Archives of Toxicology
Proper subcellular trafficking is essential to prevent protein mislocalization and aggregation. Transport of the peroxisomal enzyme d-amino acid oxidase (DAAO) appears… Continue reading Understanding renal nuclear protein accumulation: an in vitro approach to explain an in vivo phenomenon
2010 / PLoS ONE
Since the discovery that mutations in the enzyme SOD1 are causative in human amyotrophic lateral sclerosis (ALS), many strategies have… Continue reading Modification of Superoxide Dismutase 1 (SOD1) Properties by a GFP Tag – Implications for Research into Amyotrophic Lateral Sclerosis (ALS)
2012 / PLoS ONE
GAGE proteins are highly similar, primate-specific molecules with unique primary structure and undefined cellular roles. They are restricted to cells… Continue reading GAGE Cancer-Germline Antigens Are Recruited to the Nuclear Envelope by Germ Cell-Less (GCL)
2016 / PLoS ONE
Adherence of microbes to host tissues is a hallmark of infectious disease and is often mediated by a class of… Continue reading Allosteric Regulation of Fibronectin/α5β1 Interaction by Fibronectin-Binding MSCRAMMs
2013 / PLoS ONE
BteA, a 69-kDa cytotoxic protein, is a type III secretion system (T3SS) effector in the classical Bordetella, the etiological agents of… Continue reading Characterization of the N-Terminal Domain of BteA: A Bordetella Type III Secreted Cytotoxic Effector
2012 / PLoS ONE
Protein folding, refolding and degradation are essential for cellular life and are regulated by protein homeostatic processes such those that… Continue reading Identification of Regions Involved in Substrate Binding and Dimer Stabilization within the Central Domains of Yeast Hsp40 Sis1
2010 / PLoS ONE
Heat shock proteins have been implicated as endogenous activators for dendritic cells (DCs). Chronic expression of heat shock protein gp96… Continue reading Identification of gp96 as a Novel Target for Treatment of Autoimmune Disease in Mice
