Found 9617 Results / Page 343 of 481
2017 / Materials Science and Engineering: C
The work introduces Tb(III)-centered luminescence of amino-modified silica nanoparticles doped with Tb(III) complexes for cellular imaging. For these purposes water-in-oil… Continue reading Cellular imaging by green luminescence of Tb(III)-doped aminomodified silica nanoparticles
2017 / The Protein Journal
Many degenerative disorder such as Parkinsons, Alzheimers, Huntingtons disease, etc are caused due to the deposition of amyloid fibrils, formed… Continue reading Trehalose and Magnesium Chloride Exert a Common Anti-amyloidogenic Effect Towards Hen Egg White Lysozyme
2017 / Soft Matter
Polycationic polymers and DNA form soluble complexes in aqueous solution, which allows the transfer of genetic material into cells. Therefore,… Continue reading Properties of polyplexes formed through interaction between hydrophobically-modified poly(ethylene imine)s and calf thymus DNA in aqueous solution
2017 / Scientific Reports
Ubiquitin C-terminal Hydrolase-1 (UCHL1) is a deubiquitinating enzyme, which plays a key role in Parkinson’s disease (PD). It is one… Continue reading S-nitrosylation of UCHL1 induces its structural instability and promotes α-synuclein aggregation
2017 / Dalton Transactions
This study presents a few bis(histidine) ligands working to build a small peptidic model system of zinc structural sites. Ferrocene-peptide… Continue reading Metal Coordination of Ferrocene-Histidine Conjugates
2017 / RSC Advances
Protein interactions with surfactants are dependent on their physiochemical properties. The effect of cationic gemini surfactant hexanediyl-α,ω-bis-(N-(2-hydroxyethyl)-N-methylhexadecylammonium dibromide) on the… Continue reading Comparative effect of cationic gemini surfactant and its monomeric counterpart on the conformational stability and activity of lysozyme
2017 / Polymer Chemistry
Chiral sensing using fluorescent responses as output signals is an attractive technique for enantiodifferentiation in terms of its rapidity, high… Continue reading A cellulose-based chiral fluorescent sensor for aromatic nitro compounds with central, axial and planar chirality
2017 / Scientific Reports
Peptide-drug discovery using host-defense peptides becomes promising against antibiotic-resistant pathogens and cancer cells. Here, we customized the therapeutic activity of… Continue reading Mechanistic and structural basis of bioengineered bovine Cathelicidin-5 with optimized therapeutic activity
2017 / Food Analytical Methods
A novel surface-enhanced Raman scattering (SERS) response emerging from aptamers, complementary DNA (cDNA), p-aminothiophenol (PATP), and Au nanorods (GNRs) for detection… Continue reading Fabricating a Novel Raman Spectroscopy-Based Aptasensor for Rapidly Sensing Salmonella typhimurium
2017 / PLoS ONE
Calpains are calcium-activated proteases that have biomedical and biotechnological potential. Their activity is tightly regulated by their endogenous inhibitor, calpastatin… Continue reading Affinity purification of human m-calpain through an intrinsically disordered inhibitor, calpastatin
2017 / Biochimie
HAMLET (Human Alpha-Lactalbumin Made LEthal to Tumor cells), a complex of oleic acid (OA) with partially unfolded human α-lactalbumin, shows… Continue reading Augmenting the cytotoxicity of oleic acid-protein complexes: Potential of target-specific antibodies
2017 / Vaccine
Plasmodium vivax is the most widely distributed malaria species and the most prevalent species of malaria in America and Asia. Vaccine… Continue reading Generation, characterization and immunogenicity of a novel chimeric recombinant protein based on Plasmodium vivax AMA-1 and MSP119
2017 / Biochimica et Biophysica Acta (BBA) - Biomembranes
β -barrel membrane proteins (βMPs) form barrel-shaped pores in the outer membrane of Gram-negative bacteria, mitochondria, and chloroplasts. Because of the… Continue reading Engineering a Novel Porin OmpGF via Strand Replacement From Computational Analysis of Sequence Motif
2017 / Biopolymers
Most of the important genomic regions, especially the G,C rich gene promoters, consist of sequences with potential to form G,C-tetraplexes… Continue reading Magnesium and Molecular crowding of the cosolutes stabilize the i-motif structure at physiological pH
2017 / ChemBioChem
An unusually thermostable G-quadruplex is formed by a sequence fragment of a naturally occurring ribozyme, the human CPEB3 ribozyme. Strong… Continue reading The 5′-AG₅CC-3′ fragment from the human CPEB3 ribozyme forms an ultrastable parallel RNA G-quadruplex
2017 / The Journal of Biological Chemistry
The interaction of IFN-β with its receptor IFNAR1 is vital for host-protective anti-viral and anti-proliferative responses, but signaling via this… Continue reading A hot-spot on interferon alpha/beta receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling
2017 / Scientific Reports
Disease associated genetic variations often cause intracellular enzyme inactivation, dysregulation and instability. However, allosteric communication of mutational effects to distant… Continue reading Site-to-site interdomain communication may mediate different loss-of-function mechanisms in a cancer-associated NQO1 polymorphism
2017 / Nature Nanotechnology
At the molecular level, translation refers to the production of a new entity according to a template that has a… Continue reading Translation of rod-like template sequences into homochiral assemblies of stacked helical oligomers
2017 / European Journal of Pharmaceutics and Biopharmaceutics
Surfactin is a Bacillus-produced natural lipopeptide, which can overcome the epithelial cell barriers for orally delivering insulin, but its ability to… Continue reading Surfactin variants for intra-intestinal delivery of insulin
2017 / Journal of Molecular Recognition
Nowadays, understanding of interface between protein and drugs has become an active research area of interest. These types of interactions… Continue reading Elucidating the interaction of clofazimine with bovine liver catalase; a comprehensive spectroscopic and molecular docking approach
