Found 9617 Results / Page 347 of 481
2017 / Biophysical Journal
Cyclophilin catalyzes the ubiquitous process “peptidyl-prolyl cis-trans isomerization,” which plays a key role in protein folding, regulation, and function. Here, we present… Continue reading Unfolding of CPR3 Gets Initiated at the Active Site and Proceeds via Two Intermediates
2017 / Journal of Photochemistry and Photobiology A: Chemistry
A zinc bacteriochlorophyll-d analog possessing a fully π-conjugated porphyrin skeleton and an acrylate residue at the 17-position was prepared by chemical… Continue reading Self-aggregation of synthetic chlorophyll-c derivative and effect of C17-acrylate residue on bridging green gap in chlorosomal model
2017 / Organic Chemistry Frontiers
In silico screening of an in-house natural product database and confirmatory bioassays led to the identification of asperspiropene A (1) as… Continue reading Asperspiropene A, a novel fungal metabolite as an inhibitor of cancer-associated mutant isocitrate dehydrogenase 1
2017 / Journal of the Iranian Chemical Society
This article describes the interaction of fluoxymesterone (Flu) with HSA and HTF in the absence and presence of cyclodextrins (CDs)… Continue reading A comparison of the inclusion behavior of human serum albumin and holo transferrin with fluoxymesterone in the presence of three different cyclodextrins
2017 / Chinese Chemical Letters
The microbial transformation of glycyrrhetinic acid (1) by Cunninghamella blakesleana CGMCC 3.970 led to the production of five new metabolites (2–6). The… Continue reading Microbial transformation of glycyrrhetinic acid and potent neural anti-inflammatory activity of the metabolites
2017 / Protein Science
Amyloid fibrils are fibrillar deposits of denatured proteins associated with amyloidosis and are formed by a nucleation and growth mechanism.… Continue reading Heparin-induced amyloid fibrillation of β2-microglobulin explained by solubility and a supersaturation-dependent conformational phase diagram
2017 / ChemPhysChem
We report the experimental observation of nonmonotonic changes in the collective hydration of bovine serum albumin (BSA) in the presence… Continue reading Nonmonotonic Hydration Behavior of Bovine Serum Albumin in Alcohol/Water Binary Mixtures: A Terahertz Spectroscopic Investigation
2017 / Protein Science
The potential for infection by coronaviruses (CoVs) has become a serious concern with the recent emergence of Middle East respiratory… Continue reading Structural basis for dimerization and RNA binding of avian infectious bronchitis virus nsp9
2017 / Dalton Transactions
Vibrational circular dichroism (VCD) spectra were measured on the dichloromethane solutions of the resolved enantiomers of [Ir(bzq)2(phen)]+ (bzqH = benzo[h]quinoline;… Continue reading Vibrational Circular Dichroism and Single Crystal X-Ray Diffraction Analyses of [Ir(bzq)2(phen)]+ (bzq = benzo[h]quinoline; phen = 1,10-phenanthroline): Absolute Configuration and Role of CH-π Interaction in Molecular Packing
2017 / New Journal of Chemistry
An attempt of developing a chiral luminescent probe for amino acids was described. Two types of chiral iridium(III) complexes were… Continue reading Chiral phosphorescent probes for amino acids: hybrids of iridium(III) complexes with synthetic saponite
2017 / Phytochemistry
Bioguided isolation of the EtOH extract from the medicinal native plant, Ophryosporus charua, against Raphanus sativus, yielded three phenylpropanoids, charuol A [(Z)-4-((1S,2R)-3-acetoxy-1,2-dihydroxypropyl)phenyl)… Continue reading Phytotoxic phenylpropanoids isolated from Ophryosporus charua (Griseb.) Hieron.
2017 / RSC Advances
A chemical investigation of the South China Sea sponge Agelas aff. nemoechinata yielded three pairs of new enantiotopic pyrrole alkaloids nemoechines A–C (1–3), one… Continue reading Alkaloids and polyketides from the South China Sea sponge Agelas aff.nemoechinata
2017 / Scientific Reports
We report a thermodynamic and structural analysis of six extensively simplified bovine pancreatic trypsin inhibitor (BPTI) variants containing 19–24 alanines… Continue reading Crystal structures of highly simplified BPTIs provide insights into hydration-driven increase of unfolding enthalpy
2017 / Vaccine
Streptococcus pneumoniae is a serious Gram-positive pathogen that can lead to an invasive pneumococcal disease with high mortality rate. Pneumococcal capsular… Continue reading Conjugation of PEG-hexadecane markedly increases the immunogenicity of pneumococcal polysaccharide conjugate vaccine
2017 / Fitoterapia
Five new 2-(2-phenylethyl)chromone derivatives (1–5), along with eleven known compounds (6–16) were isolated from Chinese agarwood. Their structures were elucidated… Continue reading Anti-inflammatory 2-(2-phenylethyl)chromone derivatives from Chinese agarwood
2017 / Chemical Communications
The novel property of reversible regulation of parallel type G-quadruplexes with moderate temperature changes was discovered in thermoresponsive hydrogels using… Continue reading Reversible conformational changes in the parallel type G-quadruplex structure inside a thermoresponsive hydrogel
2017 / Scientific Reports
Hipposponlachnins A (1) and B (2), possessing an unprecedented tetracyclo [9.3.0.02,8.03,7] tetradecane ring system, and the probable biogenetic precursor [3,… Continue reading Unusual Anti-allergic Diterpenoids from the Marine Sponge Hippospongia lachne
2017 / Journal of Chromatography A
Targeted identification of potentially bioactive molecules from herbal medicines is often stymied by the insufficient chromatographic separation, ubiquitous matrix interference,… Continue reading An enhanced targeted identification strategy for the selective identification of flavonoid O-glycosides from Carthamus tinctorius by integrating offline two-dimensional liquid chromatography/linear ion-trap-Orbitrap mass spectrometry, high-resolution diagnostic product ions/neutral loss filtering and liquid chromatography-solid phase extraction-nuclear magnetic resonance
2017 / PLoS ONE
Viral protein U (Vpu) is a type-III integral membrane protein encoded by Human Immunodeficiency Virus-1 (HIV- 1). It is expressed… Continue reading Bacterial expression, correct membrane targeting and functional folding of the HIV-1 membrane protein Vpu using a periplasmic signal peptide
2017 / Polymer Chemistry
Construction of supramolecular chirality from achiral compounds has been exploited in small molecule, oligomer and polymer systems. However, the relationship… Continue reading Induction of Supramolecular Chirality by Chiral Solvation in Achiral Azo Polymers with Different Spacer Lengths and Push-Pull Electronical Substituents: Where will Chiral Induction Appear?
