Found 9617 Results / Page 348 of 481
2017 / Environmental Science and Pollution Research
An increasing amount of heavy metals (e.g., Cu2+) is being discharged into sewage treatment plants and is accumulating in sludge,… Continue reading Multi-spectral and thermodynamic analysis of the interaction mechanism between Cu2+ and α-amylase and impact on sludge hydrolysis
2017 / Luminescence
In the present work, the mechanism of the interaction between a β1 receptor blocker, metoprolol succinate (MS) and human serum… Continue reading Probing the mechanism of interaction of metoprolol succinate with human serum albumin by spectroscopic and molecular docking analysis
2017 / RSC Advances
Mitochondria plays a vital role in a wide range of biological processes in human health and diseases. They are considered… Continue reading pH-sensitive polymeric micelles for the Co-delivery of proapoptotic peptide and anticancer drug for synergistic cancer therapy
2017 / Journal of Natural Medicines
Two new secolignans, urticin A (1) and urticin B (2), were isolated from the ethanol extract of Urtica fissa rhizomes. Their structures… Continue reading Two new secolignans with in vitro anti-inflammatory activities from Urtica fissa rhizomes
2017 / Polymers for Advanced Technologies
Here, we describe the thermosensitive reversible phase transition behaviors of polyelectrolyte complex composed of gelatin and chitosan (G/C complex). An… Continue reading UCST-type phase transition driven by protein-derived polypeptide employing gelatin and chitosan
2017 / Biochemical and Biophysical Research Communications
Pathological TDP-43 is cleaved into various fragments. Two major groups of ∼35 and ∼25 kDa have enhanced aggregation and cytotoxicity but… Continue reading ALS-causing cleavages of TDP-43 abolish its RRM2 structure and unlock CTD for enhanced aggregation and toxicity
2017 / International Journal of Molecular Sciences
The aim of the present study was to investigate whether glycated ovalbumin (OVA) showed novel activity at the lipid-water interface.… Continue reading Ovalbumin with Glycated Carboxyl Groups Shows Membrane-Damaging Activity
2017 / Biochemical Engineering Journal
In the present study, a novel catalyst was prepared by combining cellulase enzyme complex with metal oxides as a substrate… Continue reading MgO-Fe3O4 linked cellulase enzyme complex improves the hydrolysis of cellulose from Chlorella sp. CYB2
2017 / Biomedicine & Pharmacotherapy
Bioassay-guided fractionation of the aerial part of P. cablin revealed that fraction A3 of the water extract exhibited significant xanthine oxidase inhibitory… Continue reading Phytochemicals of Pogostemon Cablin (Blanco) Benth. aqueous extract: Their xanthine oxidase inhibitory activities
2017 / Acta Biomaterialia
To reduce the side effects and enhance the anti-tumor activities of anticancer drugs in the clinic, the use of nano… Continue reading Redox-responsive mesoporous selenium delivery of doxorubicin targets MCF-7 cells and synergistically enhances its anti- tumor activity
2017 / International Journal of Biological Macromolecules
Protein misfolding and aggregation has been implicated as the cause of more than 20 diseases in humans such as Alzheimer’s… Continue reading Vitamin B12 offers neuronal cell protection by inhibiting Aβ-42 amyloid fibrillation
2017 / International Journal of Adhesion and Adhesives
The aim of this study was to provide a basis for the preparation of medical adhesives from soybean protein sources.… Continue reading Effects of guar gum on adhesion properties of soybean protein isolate onto porcine bones
2017 / Biochemistry and Biophysics Reports
Ellagic acid (EA), a natural polyphenol evidence several pharmacological benefits. The binding profile of EA with human serum albumin (HSA)… Continue reading An insight to the binding of Ellagic acid with Human serum albumin using spectroscopic and isothermal calorimetry studies
2017 / Carbohydrate Polymers
Fucoidan, a sulfated marine polysaccharide, has many potential biological functions, including anticancer activity. Recently, fucoidan has been reported to target… Continue reading Development of a new type of multifunctional fucoidan-based nanoparticles for anticancer drug delivery
2017 / International Journal of Biological Macromolecules
The interactions between lafutidine (LAF) and calf thymus DNA (ctDNA) have been investigated both experimentally and theoretically. UV–vis absorption studies… Continue reading Studies of DNA-binding properties of lafutidine as adjuvant anticancer agent to calf thymus DNA using multi-spectroscopic approaches, NMR relaxation data, molecular docking and dynamical simulation
2017 / European Journal of Medicinal Chemistry
A series of 2-arylethenyl-N-methylquinolinium derivatives were designed and synthesized based on our previous research of 2-arylethenylquinoline analogues as multifunctional agents… Continue reading Design, synthesis and evaluation of 2-arylethenyl-N-methylquinolinium derivatives as effective multifunctional agents for Alzheimer’s disease treatment
2017 / Archives of Biochemistry and Biophysics
The alpha splice variant of p73 (p73α), a homologue of the tumour suppressor p53, has at its C terminus a… Continue reading Trifluoroethanol-induced conformational transition of the C-terminal sterile alpha motif (SAM) of human p73
2017 / Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
Parkinson’s disease is characterized by the presence of insoluble and neurotoxic aggregates (amyloid fibrils) of an intrinsically disordered protein α-synuclein.… Continue reading Polyphenols in combination with β-cyclodextrin can inhibit and disaggregate α-synuclein amyloids under cell mimicking conditions: A promising therapeutic alternative
2017 / International Journal of Biological Macromolecules
Endoglucanases are key enzymes in the degradation of cellulose, the most abundant polymer on Earth. The aim of this work… Continue reading BIOCHEMICAL AND BIOPHYSICAL PROPERTIES OF A METAGENOME-DERIVED GH5 ENDOGLUCANASE DISPLAYING AN UNCONVENTIONAL DOMAIN ARCHITECTURE
2017 / Journal of Molecular Liquids
Due to the increasing usage of silver nanoparticles in biomedical applications, it becomes important to understand their interaction with biomolecules… Continue reading Spectroscopic studies on the interactions of bovine serum albumin in presence of silver nanorods
